Endothelin-1 in human skin: Immunolocalization, receptor binding, mRNA expression, and effects on cutaneous microvascular endothelial cells

Journal of Investigative Dermatology

Volumn 97, Issue 4, 1991, Pages 618-623

  Bull, Helen A ^a   Bunker, Christopher B ^a   Terenghi, Georgio ^b   Springall, David R ^b   Zhao, Yidan ^b   Polak, Julia M ^b   Dowd, Pauline M ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3,4,5 TRIMETHOXYBENZOIC ACID 8 (DIMETHYLAMINO)OCTYL ESTER; CALCIUM; EGTAZIC ACID; ENDOTHELIN 1; NIFEDIPINE; UNCLASSIFIED DRUG;

ARTICLE; BLOOD VESSEL TONE; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; MICROVASCULATURE; NORMAL HUMAN; PRIORITY JOURNAL; SKIN BLOOD VESSEL;

CALCIUM; CELLS, CULTURED; CYCLIC AMP; DINOPROSTONE; ENDOTHELINS; ENDOTHELIUM, VASCULAR; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; RECEPTORS, CELL SURFACE; RECEPTORS, ENDOTHELIN; RNA, MESSENGER; SKIN; SUPPORT, NON-U.S. GOV'T;

EID: 0026076104     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12483000     Document Type: Article

References (35)

1. M. Yanagisawa H. Kurihara S. Kimura Y. Tomobe M. Kobayashi Y. Mitsiu Y. Yazaki K. Goto T. Masaki A novel potent vasoconstrictor peptide produced by vascular endotliclial cells Nature 332 1988 411 415
2. P. Vigne R. Marsault J.P. Breittmayer C. Frelin Endothelin stimulates phosphatidylinositol hydrolysis and DNA synthesis in brain capillary endothelial cells Biochem J 266 1990 415 420
3. M.W. MacCumber C.A. Ross B.M. Glaser S.H. Snyder Endothelin: visualization of mRNAs by in situ hybridization provides evidence for local action Proc Natl Acad Sci USA 86 1989 7285 7289
4. J.B. Clarke N. Benjamin S.W. Larkin D.J. Webb G.J. Davies A. Maseri Endothelin is a potent long-lasting vasoconstrictor in man Am J Physiol 257 1989 2033 2035
5. S.D. Brain D.C. Crossman T.L. Buckley T.J. Williams Endothelin-1: demonstration of potent effects on the microcirculation of humans and other species J Cardiovasc Pharmacol 13 1989 147 149
6. T. Lewis The Blood Vessels of the Human Skin and their Responses 1927 Shaw & Son London
7. P.M. Dowd R.D.R. Camp M.W. Greaves In vivo effects of human recombinant interleukin-1α (IL-1α) in normal human skin Skin Pharmacol 1 1988 30 38
8. C.B. Bunker J.C. Foreman P.M. Dowd Digital cutaneous vascular responses to histamine and neuropeptides in Raynaud's phenomenon J Invest Dermatol 96 1991 314 317
9. 2 from human dermal microvascular endothelial cells Br J Dermatol 122 1990 153 164
10. H.A. Bull P.M. Dowd Cutaneous endothelial cell responses to histamine and substance P Br J Dermatol 122 1990 275 276
11. 2α in human skin following ultraviolet B irradiation Br J Clin Pharmacol 10 1980 453 457
12. 2 and prostaglandin F2α in epidermis of psoriasis Proc Natl Acad Sci USA 72 1975 5130 5134
13. M.W. Greaves J. Sondergaard W. MacDonald-Gibson Recovery of prostaglandins in human cutaneous inflammation Br Med J 2 1971 258 260
14. P. Crunkhorn A.L. Willis Cutaneous reactions to intradermal prostaglandins Br J Pharmacol 41 1971 49 56
15. R.D.R. Camp F.M. Cunningham P.M. Woollard P.M. Dowd A. Kobza Black E. Wong S.D. Brain M.W. Greaves The inflammatory properties of eicosanoids in human skin GA. Higgs TJ. Williams Inflammatory Mediators 1985 MacMillan Press Edinburgh, UK 49
16. K. Sakata H. Osaki S-C. Kwon H. Karaki Effects of endothelin on the mechanical activity and cytosolic calcium levels of various types of smooth muscle Br J Pharmacol 98 1989 483 492
17. K. Goto Y. Kasuya N. Matsuki Y. Takuwa H. Kurihara S. Ishikawa S. Kimura M. Yanagisawa T. Masaki Endothelin activates dihydropyridine-sensitive, voltage-dependent Ca2+ channels in vascular smooth muscle Proc Natl Acad Sci USA 86 1989 3915 3918
18. Y. Hirata H. Yoshimi S. Takata T.X. Watanabe S. Kumagai K. Nakajima S. Sakakibara Cellular mechanisms of action by a novel vasoconstrictor endothelin in cultured smooth muscle cells Biochem Biophys Res Commun 154 1988 868 875
19. L.L. Muldoon K.D. Rodland M.L. Forsythe B.E. Magun Stimulation of phosphatidylinositol hydrolysis, diacylglycerol release and gene expression in response to endothelin, a potent new agonist for fibroblasts and smooth muscle cells J Biol Chem 264 1989 8529 8536
20. 125I-labelled ligands in quantitative autoradiography Neurosci Lett 81 1987 345 350
21. P.M. Davison K. Bensch M.A. Karasek Isolation and growth of endothelial cells from the microvessels of the newborn foreskin in cell culture J Invest Dermatol 75 1980 316 321
22. Q.A. Hamid J. Wharton G. Terenghi C.J.S. Hassal J. Aimi K.M. Taylor H. Nakazato J. Dixon G. Burnstock J.M. Polak Localization of atrial natriuretic peptide mRNA and immunoreactivity in the rat heart and human atrial appendage Proc Natl Acad Sci USA 84 1987 6760 6764
23. A. Giaid S.J. Gibson N.B.N. Ibrahim S. Legon S.R. Bloom M. Yanagisawa T. Masaki I.M. Varudell J.M. Polak Endothelin-1, an endothelium-derived peptide is expressed in neurons of the human spinal cord and dorsal root ganglia Proc Natl Acad Sci USA 86 1989 7634 7638
24. H.A. Bull R.M. Pittilo N. Woolf S.J. Machin The effects of nicotine on human endothelial cell release of prostaglandins and morphology Br J Exp Pathol 69 1988 413 422
25. 2+ and cyclic AMP in the regulation of the production of prostacyclin by vascular endothelium Proc Natl Acad Sci USA 79 1982 495 499
26. A. Lückhoff U. Pohl A. Mülsch R. Busse Differential role of extra- and intracellular calcium in the release of EDRF and prostacyclin from cultured endothelial cells Br J Pharmacol 95 1988 189 196
27. H.A. Bull P.M. Dowd Interleukin-1 potentiates histamine induced release of prostacyclin from human endothelial cells Br J Pharmacol 101 1990 703 709
28. R.W. Dougherty J.E. Niedel Cytoplasmic calcium regulates phorbol diester binding affinity in intact phagocytes J Biol Chem 261 1986 4097 4100
29. M.S. Simonson M.J. Dunn Endothelin-1 stimulates contraction of rat glomerular mesangial cells and potentiates beta-adrenergic-mediated cyclic adenosine monophosphate accumulation J Clin Invest 85 1990 790 797
30. A.F.A. Brotherton D.E. Macfarlane J.C. Hoak Prostacyclin biosynthesis in vascular endothelium is not inhibited by cyclic AMP. Studies with 3-isobutyl-l-methylxanthine and forskolin Thromb Res 28 1982 637 647
31. E.W. Horton Prostaglandins and smooth muscle Br Med Bull 35 1979 295 300
32. R. Andersson K. Nilsson J. Wikberg S. Johansson L. Lundholm Cyclic nucleotides and contraction of smooth muscle Advan Cyclic Nuclcotide Res 5 1975 153 162
33. 2+ J Biol Chem 264 1989 5339 5342
34. H. Rasmussen D.B.P. Goodman Calcium and cyclic nucleotides Physiol Rev 57 1977 421 509
35. 2+ in cultured aortic smooth muscle cells J Biochem (Tokyo) 104 1988 795 800