Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene

Nature

Volumn 353, Issue 6347, 1991, Pages 844-846

  Chartier Harlin, Marie Christine ^a   Crawford, Fiona ^a   Houlden, Henry ^a   Warren, Andrew ^b   Hughes, David ^a   Fidani, Liana ^a   Goate, Alison ^a   Rossor, Martin ^a   Roques, Penelope ^a   Hardy, John ^a   Mullan, Mike ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; ARTICLE; CASE REPORT; FAMILY; HUMAN; MUTATION; PRIORITY JOURNAL;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; BASE COMPOSITION; BASE SEQUENCE; CASE REPORT; CODON; EXONS; FEMALE; GENES, STRUCTURAL; HUMAN; MALE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGODEOXYRIBONUCLEOTIDES; PEDIGREE; POLYMERASE CHAIN REACTION; SUPPORT, NON-U.S. GOV'T;

EID: 0026075602     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/353844a0     Document Type: Article

References (20)

1. Goate, A. ef al. Nature349, 704-706 (1991).
2. Hardy, J. et al. Lancet337, 1342-1343 (1991).
3. van Duijn, C. M. et al. Lancet337, 978 (1991).
4. Naruse, S. et al. Lancet337, 978-979 (1991).
5. Yoshikai, S., Sasaki, H., Dohura, K., Furuya, H. and Sakaki, Y. Gene87, 257-263 (1990).
6. Orita, M., Suzuki, Y., Sekiya, T. and Hayashi, K, Genomics5, 874-879 (1989).
7. Orita, M., Sekiya, T. and Hayashi, K. Genomics8, 271-278 (1990).
8. McKhann, G. et al. Neurology34, 939-944 (1984).
9. Tanzi, R. E. and Hyman, B. T. Nature350, 564 (1991).
10. Rumble, B. er al. New Engl. J. Med.320, 1446-1452 (1989).
11. Johnstone, E. M., Chaney, M. O., Norris, F. H., Pascual, R. and Little, S. P, Molec. Brain Res.10, 299-305 (1991).
12. Klausner, R. D. and Harford, J. B. Science246, 870-872 (1989).
13. Harrison, P. J., Barton, A. J. L. and Pearson, R. C. A. Neuro Rep.2, 152-154 (1991).
14. Esch, F. S. et al. Science248, 1122-1124 (1990).
15. Master, C. et al Proc. natn. Acad. Sci. U.S.A.82, 4245-4249 (1985).
16. Glenner, G. G. and Wong, C. W. Biochem. biophys. Res. Commun.120, 885-890 (1984).
17. Lathrop, G., Lalouel, J. M., Julier, C. and Ott, J. Proc. natn. Acad. Sci. U.S.A.81, 3443-34461984).
18. Chartier Harlin, M. C. et al. Neurosci. Lett.129, 134-135 (1991).
19. Levy, E. et al Science248,1124-1126 (1990).
20. Murrell, J., Farlow, M., Ghetti, B. and Benson, M. Science253, 97-98 (1991).