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Volumn 204, Issue 1, 1991, Pages 41-48

The α2-adrenoceptor antagonist efaroxan modulates K+ATP channels in insulin-secreting cells

Author keywords

Adrenoceptors; Efaroxan; Imidazoline; Insulin secretion; k+ATP channels; Patch clamp

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIC AMP; DIAZOXIDE; EFAROXAN; IDAZOXAN; POTASSIUM CHANNEL; RUBIDIUM 86;

EID: 0026069841     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(91)90833-C     Document Type: Article
Times cited : (102)

References (39)
  • 2
    • 0025186956 scopus 로고
    • Tolbutamide excites rat glucoreceptive ventromedial hypothalamic neurones by indirect inhibition of ATP-K channels
    • (1990) Br. J. Pharmacol. , vol.101 , pp. 531
    • Ashford1    Boden2    Treherne3
  • 6
    • 0025173880 scopus 로고
    • Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels
    • (1990) Eur. J. Pharmacol. , vol.176 , pp. 97
    • Chan1    Morgan2
  • 9
    • 0021187646 scopus 로고
    • Intracellular ATP directly blocks K channels in pancreatic B-cells
    • (1984) Nature , vol.311 , pp. 273
    • Cook1    Hales2
  • 10
    • 0024375652 scopus 로고
    • Protein phosphorylation is required for diazoxide to open ATP-sensitive potassium channels in RINm5F insulin secreting cells
    • (1989) FEBS Lett. , vol.250 , pp. 262
    • Dunne1
  • 11
    • 0025190932 scopus 로고
    • Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells
    • (1990) Br. J. Pharmacol. , vol.99 , pp. 169
    • Dunne1
  • 12
    • 0026092353 scopus 로고
    • Potassium selective ion channels in insulin-secreting cells: physiology, pharmacology and their role in stimulus-secretion coupling
    • (1991) Biochim. Biophys. Acta , vol.1071 , pp. 67
    • Dunne1    Petersen2
  • 13
    • 0022913585 scopus 로고
    • ATP-sensitive K channels in an insulin secreting cell-line are inhibited by D-glyceraldehyde and activated by membrane permeabilization
    • (1986) J. Membr. Biol. , vol.93 , pp. 271
    • Dunne1    Findlay2    Petersen3    Wollheim4
  • 16
    • 0016829106 scopus 로고
    • Effects of phentolamine and perfusion with glucose on insulin release from isolated perfused pancreas from fasted and fed rats
    • (1975) Diabetalogia , vol.11 , pp. 407
    • Efendic1    Cerasi2    Luft3
  • 19
    • 84872249908 scopus 로고
    • Maintenance of human normal cells in continuous culture preliminary report cultivation of mesoblastic tumors and normal cells and notes on methods of cultivation
    • (1936) The American Journal of Cancer , vol.27 , pp. 45
    • Gey1    Gey2
  • 20
    • 0018418119 scopus 로고
    • + permeability of pancreatic islet cells
    • (1979) Nature , vol.280 , pp. 66
    • Henquin1
  • 22
    • 0020077795 scopus 로고
    • Hypoglycemic action of 2-[2-(4,5-dihydro(H-imidazol-2-yl)-1 phenylethyl] pyridine dihydrochloride resquihydrate (DG-5128), a new hypoglycemic agent
    • (1982) Arzneim. Forsch Drug Res. , vol.32 , pp. 39
    • Kameda1    Ono2    Ahiko3
  • 26
    • 0019620392 scopus 로고
    • Pancreatic neuroendocrinology; peripheral neural mechanisms in the regulation of the islets of Langerhans
    • (1981) Endocr. Rev. , vol.2 , pp. 471
    • Miller1
  • 27
  • 28
    • 0021150914 scopus 로고
    • Stimulation of insulin secretion from isolated rat islets of Langerhans by melittin
    • (1984) Biosci. Rep. , vol.4 , pp. 665
    • Morgan1    Montague2
  • 33
    • 0022557304 scopus 로고
    • Calcium and delayed potassium current in mouse pancreatic β-cells under voltage-clamp conditions
    • (1986) J. Physiol. , vol.374 , pp. 531
    • Rorsman1    Trube2
  • 37
    • 0023899887 scopus 로고
    • Augmentation of glucose-induced insulin secretion by pertussis toxin vaccine, phentolamine and benextramine; involvement of mechanisms additional to prevention of the inhibitory actions of catecholamines in rats
    • (1988) Acta Endocrinol. , vol.188 , pp. 89
    • Smith1    Furman2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.