Phenotypic and functional stages in the intrathymic development of αβ T cells

Immunology Today

Volumn 12, Issue 2, 1991, Pages 65-70

  Nikolić Žugić, Janko ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE ANTIGEN; T LYMPHOCYTE RECEPTOR;

CELL MATURATION; HUMAN; MOUSE; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE; THYMUS;

ANIMAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL DIVISION; CELL MOVEMENT; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; MICE; MODELS, BIOLOGICAL; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-2; SELECTION (GENETICS); SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTE SUBSETS; THYMUS GLAND;

EID: 0026067467     PISSN: 01675699     EISSN: None     Source Type: Journal    
DOI: 10.1016/0167-5699(91)90160-U     Document Type: Review

References (67)

1. T cell receptor expression on immature thymocytes within vivo andin vitro precursor potential
2. Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection.
3. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
4. T cell tolerance by clonal elimination in the thymus