Crystal Structure of Unliganded Escherichia coli Dihydrofolate Reductase. Ligand-Induced Conformational Changes and Cooperativity in Binding

Biochemistry

Volumn 30, Issue 8, 1991, Pages 2227-2239

  Bystroff, Christopher ^a   Kraut, Joseph ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; METHOTREXATE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; CRYSTAL STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; APOENZYMES; BINDING SITES; ESCHERICHIA COLI; LIGANDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TETRAHYDROFOLATE DEHYDROGENASE; X-RAY DIFFRACTION;

ESCHERICHIA COLI;

EID: 0026065644     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00222a028     Document Type: Article

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