Inhibition of HIV and SIV infectivity by blockade of α-glucosidase activity

Virology

Volumn 181, Issue 1, 1991, Pages 180-192

  Ratner, Lee ^a   Heyden, Nancy Vander ^a   Dedera, Douglas ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLUCOSIDASE; ANTIVIRUS AGENT; MIGLUSTAT; OLIGOSACCHARIDE;

ARTICLE; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS INFECTION;

ALPHA-GLUCOSIDASES; ANIMAL; ANTIVIRAL AGENTS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSAMINE; HIV; HUMAN; KINETICS; MODELS, BIOLOGICAL; OLIGOSACCHARIDES; PLAQUE ASSAY; RECOMBINATION, GENETIC; RNA-DIRECTED DNA POLYMERASE; SIV; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; VACCINIA VIRUS; VIRAL ENVELOPE PROTEINS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; VACCINIA;

EID: 0026064060     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/0042-6822(91)90483-R     Document Type: Article

References (66)

1. The envelope glycoproteins of the human immunodeficiency virus contain different types of oligosaccharides
2. Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III
3. Oligosaccharide modifications and the site of processing of gPr92env, the precursor for the viral glycoproteins of Rous sarcoma virus
4. Identification of the fusion peptide of primate immunodeficiency viruses
5. Mutational analysis of the human immunodeficiency virus type 1 env gene product proteolytic cleavage site
6. The biology and molecular biology of HIV
7. Effect of tunicamycin on cell fusion induced by Mason-Pfizer monkey virus
8. The phorbol ester TPA strongly inhibits HIV-1-induced syncytia formation but enhances virus production: possible involvement of protein kinase C pathway
9. Attenuation of HIV-1 infectivity by an inhibitor of oligosaccharide processing
10. Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: Effects of monensin on glycosylation and transport
11. Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein
12. Evidence that a precursor glycoprotein is cleaved to yield the major glycoprotein of avian tumor virus
13. A human serum mannose-binding protein inhibits in vitro infection by the human immunodeficiency virus
14. A syncytia assay for human immunodeficiency virus type 1 (HIV-1) envelope protein and its use in studying HIV-1 mutations
15. Model for intracellular folding of the human immunodeficiency virus type 1 gp120
16. Role of N-linked glycans in the interaction between the envelope glycoprotein of human immunodeficiency virus and its CD4 cellular receptor. Structural enzymatic analysis
17. Role of N-linked glycans of envelope glycoproteins in infectivity of human immunodeficiency virus type 1
18. The Sor gene of HTLV-III/LAV modulates virus propagation in vitro
19. Mutational analysis of the cleavage sequence of the human immunodeficiency virus type I envelope glycoprotein precursor gpl 60
20. The role of mononuclear phagocytes in HTLV-III/LAV infection
21. Carbohydrates of human immunodeficiency virus: Structure of oligosaccharides linked to the envelope glycoprotein 120
22. Site-specific mutagenesis identifies amino acid residues critical in prohormone processing
23. Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase
24. Correlation between carbohydrate structures on the envelope glycoprotein gpl20 of HIV-1 and HIV-2 and syncytium inhibition with lectins
25. Inhibition of human immunodeficiency virus (HIV) infection in vitro by anti-carbohydrate monoclonal antibodies: Peripheral glycosylation of HIV envelope glycoprotein gpl20 may be a target for virus neutralization
26. Glycosylatlon of the envelope glycoprotein gp130 of simian immunodeficiency virus from sooty mangabey (Cercocebus atys)
27. Alterations in T4 (CD4) protein and mRNA synthesis in cells infected with HIV
28. Characterization of the secreted, mature gp120 and gp160 of the human immunodeficiency virus type 1. AIDS Res
29. Depletion of the surface CD4 molecule by the envelope protein of human immunodeficiency virus expressed in a human CD4+ monocytoid cell line
30. Interplay between carbohydrate in the stalk and the length of the connecting peptide determines the cleavability of influenza virus hemagglutinin
31. Comparison of simian immunodeficiency virus isolates
32. Class E Thy-1 negative mouse lymphoma cells utilize an alternative pathway of oligosaccharide processing to synthesize complex-type oligosaccharides
33. Assembly of asparaginelinked oligosaccharides
34. Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1
35. Rapid and efficient site-specific mutagenesis without phenotypic selection
36. Role of envelope glycoprotein carbohydrate in human immunodeficiency virus (HIV) infectivity and virus-induced cell fusion
37. Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein
38. Golgi endo-alpha-d-mannosi-dase from rat liver, a novel N-linked carbohydrate unit processing enzyme
39. The construction and characterisation of vaccinia virus recombinants expressing foreign genes
40. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
41. Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gpl 20 and the surface antigen CD4: Role of carbohydrate in binding and cell fusion
42. Endoproteolytic cleavage of gpl60 is required forthe activation of human immunodeficiency virus
43. Carbohydrate structures of the human immunodeficiency-virus (HIV) recombinant envelope glycoprotein gpl 20 produced in Chinese-hamster ovary cells
44. Diversity of oligosaccharide structures on the envelope glycoprotein gpl20 of human immunodeficiency virus 1 from the lymphoblastoid cell line H9: Presence of complex-type oligosaccharides with bisecting N-acetylglucosamine residues
45. Role of protein N-glycosylation in pathogenesis of human immunodeficiency virus type 1
46. Antibody-independent, complement-mediated enhancement of HIV-1 infection by mannosidase I and II inhibitors
47. Characterization of recombinant gp120 and gp160 from HIV-1: Binding to monoclonal antibodies and soluble CD4
48. Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1
49. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
50. Glycosylation and intracellular transport of membrane glycoproteins encoded by murine leukemia viruses. Inhibition by amino acid analogues and by tunicamycin
51. In animals infected by bovine leukemia virus (BLV) antibodies to envelope glycoprotein gp51 are directed against the carbohydrate moiety
52. Complete nucleotide sequences of functional clones of the AIDS virus
53. Complete nucleotide sequence of the AIDS virus, HTLV-III
54. A lectlnresistant mouse lymphoma cell line is deficient in glucosidase II a glycoprotein-processing enzyme
55. Transmembrane envelope glycoproteins of HIV-2 and SIV-mac exist as homodimers
56. Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis
57. Relationship of G IX antigen expression to the glycosylation of murine leukemia virus glycoprotein
58. Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity
59. Intracellular processing of the gp160 HIV-1 envelope precursor: Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex
60. A chink in HIV's armour?
61. Inhibition of human immunodeficiency virus infectivity by chloroquine
62. Functional contribution of cysteine residuesto the human immunodeficiency virus type 1 envelope
63. Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine
64. Expression and characterization of a functional human immunodeficiency virus envelope glycoprotein in insect cells
65. Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gpl60
66. In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity