Genotoxicity under extreme culture conditions. A report from ICPEMC task group 9

Mutation Research/Reviews in Genetic Toxicology

Volumn 257, Issue 2, 1991, Pages 147-205

  Scott, David ^a   Galloway, Sheila M ^b   Marshall, Richard R ^c   Ishidate Jr , Motoi ^d   Brusick, David ^e   Ashby, John ^f   Myhr, Brian C ^e  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

^c Hazleton Microtest ^*  (United Kingdom)

^d NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^e Hazleton Laboratories America ^*  (United States)

^f AKZO NOBEL CENTRAL RESEARCH   (Netherlands)

Author keywords

Culture conditions, extreme; Genotoxicity, extreme culture conditions

Indexed keywords

MUTAGENIC AGENT; TOXIN;

ANIMAL; DNA DAMAGE; HUMAN; MUTAGEN TESTING; REVIEW; SENSITIVITY AND SPECIFICITY; CARCINOGENESIS; CHROMOSOME ABERRATION; CYTOTOXICITY; GENOTOXICITY; METABOLIC ACTIVATION; MUTATION; NONHUMAN; PRIORITY JOURNAL; TOXICITY TESTING;

ANIMALS; DNA DAMAGE; HUMANS; MUTAGENICITY TESTS; MUTAGENS; SENSITIVITY AND SPECIFICITY; TOXINS, BIOLOGICAL;

EID: 0026062312     PISSN: 01651110     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-1110(91)90024-P     Document Type: Article

References (193)

1. Clastogenicity in vitro of the Na, K, Ca and Mg salts of saccharin; and of magnesium chloride; consideration of significance
2. Classification according to chemical structure, mutagenicity to Salmonella and level of carcinogenicity of a further 42 chemicals tested for carcinogenicity by the U.S. National Toxicology Program
3. Induction of morphological transformation in mouse C3H/10T1/2 clone 8 cells and chromosomal damage in hamster A(T1)C1-3 cells by cancer chemotherapeutic agents.
4. Beef extract mutagens, and not liver S9, increase mutation frequency in the Ames test
5. Genotoxicity of ethyl carbamate in the Drosophila wing spot test: dependence on genotype-controlled metabolic capacity
6. The impact of toxicity on carcinogenicity studies: implications for risk assessment
7. EXPERIMENTALLY INDUCED CHROMOSOME ABERRATIONS IN PLANTS: I. THE PRODUCTION OF CHROMOSOME ABERRATIONS BY CYANIDE AND OTHER HEAVY METAL COMPLEXING AGENTS
8. Registry of Toxic Effects of Chemical Substances
9. Editorial introduction
10. Sister chromatid exchanges and chromosomal aberrations induced in human lymphocytes by the cytostatic drug adriamycin in vivo and in vitro
11. Chromosome changes and in vitro transformation of hamster embryonic lung cells induced by dimethylnitrosamine in combination with an activation system. A preliminary note.
12. An evaluation of the L5178Y TK+/− mouse lymophoma forward mutation assay using 42 chemicals