Delivery systems for gene therapy

Biotherapy

Volumn 3, Issue 1, 1991, Pages 87-95

  Wu, George Y ^a   Wu, Catherine H ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

asialoglycoproteins; genes; hepatocytes; receptor mediated endocytosis; targeting

Indexed keywords

ASIALOGLYCOPROTEIN; CHLORAMPHENICOL ACETYLTRANSFERASE; DNA; RECEPTOR;

CELL LINE; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; REVIEW;

ANIMAL; ASIALOGLYCOPROTEIN RECEPTOR; ASIALOGLYCOPROTEINS; CELL LINE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA, BACTERIAL; DRUG CARRIERS; GENE THERAPY; LIVER; RATS; RECEPTORS, IMMUNOLOGIC; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION;

EID: 0026060779     PISSN: 0921299X     EISSN: 15738280     Source Type: Journal    
DOI: 10.1007/BF02175102     Document Type: Article

References (34)

1. A new technique for the assay of infectivity of human adenovirus 5 DNA
2. Gene transfer method for transient gene expression, stable transformation, and co-transformation of suspension cell cultures
3. Enhancer-dependent expression of human k immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation
4. Translation of mRNA injected into Xenopus oocytes is specifically inhibited by antisense RNA
5. Transfection of mammalian cells with plasmid DNA by scrape-loading and sonication loading
6. Liposome-mediated DNA transfer in eukaryotic cells
7. Entrapment of a bacterial plasmid in phospholipid vesicles: Potential for gene transfer
8. Development of retrovirus vectors useful for expressing genes in cultured murine embryonal cells and hematopoietic cells in vivo
9. High level recombinant gene expression in rabbit endothelial cells transduced by retro-viral vectors
10. Direct transfection of viral and plasmid DNA into liver or spleen of mice
11. Direct introduction of genes into rats and expression of the genes
12. In vivo expression of rat insulin after intravenous administration of the liposome-entrapped gene for rat insulin 1
13. pH-sensitive immunoliposomes mediate target-cell specific delivery and controlled expression of a foreign gene in mouse
14. Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene
15. Introduction of purified genes into mammalian cells
16. Gene transfer into hemotopoietic cells from normal and cyclic hematopoietic dogs using retroviral vectors
17. Prospects for gene therapy for immunodeficiency diseases
18. Retrovirus-mediated transduction of adult hepatocytes
19. Correction of the genetic defect in hepatocytes from the Watenabe heritable hyperlipidemic rabbit
20. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins
21. The galactose specific recognition system of mammalian liver: Receptor distribution on the hepatocyte surface
22. Low temperature selectively inhibits fusion of pinocytic vesicles and lysosomes during heterophagy of125I-asialofetuin by the perfused rat liver
23. A model for the specific rescue of normal hepatocytes during methotrexate treatment of hepatic malignancy
24. Acetaminophen hepatotoxicity and targeted rescue: A model for specific chemotherapy for hepatocellular carcinoma
25. Targeted antagonism of galactosamine toxicity in normal rat hepatocytes in vitro
26. Biological activity of the antitumor protein neocarzinostatin coupled to a monoclonal antibody by N-succinimidyl 3-(2-pyridylthio)-propionate
27. Cleavage of structural proteins during assembly of the head of bacteriophage T4
28. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
29. Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro
30. Human growth hormone as a reporter gene in regulation studies employing transient gene expression
31. Receptor-mediated gene delivery and expression in vivo
32. Hormonal control of rat liver regeneration
33. Targeting genes: Delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo