Transforming growth factor β1 expression and effect in aortic smooth muscle cells from spontaneously hypertensive rats

Hypertension

Volumn 17, Issue 6 SUPPL. 2, 1991, Pages 896-901

  Hamet, Pavel ^a,b   Hadrava, Vratislav ^a   Kruppa, Ursula ^a   Tremblay, Johanne ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Contact inhibition; Essential hypertension; Growth substances; Proto oncogenes; Spontaneously hypertensive rats; Vascular smooth muscle

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL MODEL; AORTA; CONFERENCE PAPER; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR SMOOTH MUSCLE;

ANIMAL; AORTA; CELL COUNT; CELL DIVISION; CELLS, CULTURED; DNA; G1 PHASE; MALE; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; THYMIDINE; TRANSFORMING GROWTH FACTOR BETA;

EID: 0026056324     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.17.6.896     Document Type: Article

References (27)

1. Folkow B: Cardiovascular structural adaptation: Its role in the initiation and maintenance of primary hypertension. Clin Sci Mol Med 1978;55:3S-22S
2. Mulvany MJ, Baandrup U, Gundersen HJG: Evidence for hyperplasia in mesenteric resistance vessels of spontaneously hypertensive rats using a three-dimensional disector. Circ Res 1985;57:794-800
3. Yamori Y, Igawa T, Kanbe T, Kihara M, Nara Y, Horie R: Mechanisms of structural vascular changes in genetic hypertension: Analyses on cultured vascular smooth muscle cells from spontaneously hypertensive rats. Clin Sci 1981;61: 121S-123S
4. Hamet P, Hadrava V, Kruppa U, Tremblay J: Vascular smooth muscle cell hyperresponsiveness to growth factors in hypertension. J Hypertens 1988;6(suppl 4):S36-S39
5. Scott-Burden T, Resink TJ, Baur U, Burgin M, Buhler FR: Epidermal growth factor responsiveness in smooth muscle cells from hypertensive and normotensive rats. Hypertension 1989;13:295-304
6. Hadrava V, Tremblay J, Hamet P: Abnormalities in growth characteristics of aortic smooth muscle cells in spontaneously hypertensive rats. Hypertension 1989;13:589-597
7. Scott-Burden T, Resink TJ, Burgin M, Buhler FR: Extracellular matrix: Differential influence on growth and biosynthesis patterns of vascular smooth muscle cells from SHR and WKY rats. J Cell Physiol 1989;141:267-274
8. Penttinen RP, Kobayashi S, Bornstein P: Transforming growth factor β increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. Proc Natl Acad Sci USA 1988;85:1105-1108
9. Ignotz RA, Massagué J: Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 1986; 261:4337-4345
10. Roberts AB, Anzano MA, Wakefield LM, Roche NS, Stern DF, Sporn MB: Type β transforming growth factor: A bifunctional regulator of cellular growth. Proc Natl Acad Sci U S A 1985;82:119-123
11. Assoian RK, Komoriya AK, Meyers CA, Miller DM, Sporn MB: Transforming growth factor-β in human platelets. J Biol Chem 1983;258:7155-7160
12. Assoian R, Sporn MB: Type β transforming growth factor in human platelets: Release during platelet degranulation and action on vascular smooth muscle cells. J Cell Biol 1986;102: 1217-1223
13. Sporn MB, Roberts AB, Wakefield LM, Assoian RK: Transforming growth factor-β: Biological function and chemical structure. Science 1986;233:532-534
14. Majack RA: Beta-type transforming growth factor specifies organizational behavior in vascular smooth muscle cell cultures. J Cell Biol 1987;105:465-471
15. Goodman LV, Majack RA: Vascular smooth muscle cells express distinct transforming growth factor-β receptor phenotypes as a function of cell density in culture. J Biol Chem 1989;264:5241-5244
16. 1 positively regulates its own expression in normal and transformed cells. J Biol Chem 1988;263:7741-7746
17. 1 is mediated by the AP-1 complex. Mol Cell Biol 1990;10:1492-1497
18. Sarzani R, Brecher P, Chobanian AV: Growth factor expression in aorta of normotensive and hypertensive rats. J Clin Invest 1989;83:1404-1408
19. Hamet P, Pang SC, Tremblay J: Atrial natriuretic factor-induced egression of cyclic guanosine 3′:5′-monophosphate in cultured vascular smooth muscle and endothelial cells. J Biol Chem 1989;264:12364-12369
20. Franks DJ, Plamondon J, Hamet P: An increase in adenylate cyclase activity precedes DNA synthesis in cultured vascular smooth muscle cells. J Cell Physiol 1984;119:41-45
21. Hadrava V, Tremblay J, Hamet P: Intrinsic factors involved in vascular smooth muscle cell proliferation in hypertension. Clin Invest Med (in press)
22. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-169
23. Curran T, Teich NM: Candidate product of the FBJ murine osteosarcoma virus oncogene: Characterization of a 55,000-dalton phosphoprotein. J Virol 1982;42:114-122
24. Derynck R, Jarrett JA, Chen EY, Goeddel DV: The murine transforming growth factor-β precursor. J Biol Chem 1986;261: 4377-4379
25. Feinberg AP, Vogelstein B: A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983;132:6-13
26. Owens GK, Geisterfer AAT, Yang YWH, Komoriya A: Transforming growth factor-β-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells. J Cell Biol 1988;107:771-780
27. Majack RA, Majesky MW, Goodman LV: Role of PDGF-A expression in the control of vascular smooth muscle cell growth by transforming growth factor-β. J Cell Biol 1990;111: 239-247