Sulfonylbenzoyl-Nitrostyrenes: Potential Bisubstrate Type Inhibitors of the EGF-Receptor Tyrosine Protein Kinase

Journal of Medicinal Chemistry

Volumn 34, Issue 8, 1991, Pages 2328-2337

  Traxler, Peter M ^a   Wacker, Oskar ^a   Bach, Ha L ^a   Geissler, Johanna F ^a   Kump, Wilhelm ^a   Meyer, Thomas ^a   Regenass, Urs ^a   Roesel, Johannes L ^a   Lydon, Nicholas ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN KINASE;

ARTICLE; AUTOPHOSPHORYLATION; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANGIOTENSIN II; ANIMAL; BENZOATES; CELL DIVISION; CELL LINE; CHEMISTRY; COMPUTER SIMULATION; CRYSTALLOGRAPHY; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; KERATINOCYTES; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NITRO COMPOUNDS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASE; RECEPTOR, EPIDERMAL GROWTH FACTOR; STYRENES; SULFONES;

EID: 0026055319     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00112a003     Document Type: Article

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