Chimeric human immunodeficiency virus type 1/type 2 reverse transcriptases display reversed sensitivity to nonnucleoside analog inhibitors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 88, Issue 21, 1991, Pages 9878-9882

  Shih, Cheng Kon ^a   Rose, Janice M ^a   Hansen, Gale L ^a   Wu, Joe C ^a   Bacolla, Albino ^a   Griffin, Johanna A ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

3 azido 2 ,3 dideoxythymidine; AIDS; Nevirapine (BI RG 587); Tetrahydroimidazo 4,5,1 jk 1,4 benzodiazepin 2(1H) one and thione

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

ANTIVIRUS AGENT; CHIMERIC PROTEIN; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE; TETRAHYDROIMIDAZO[4,5,1 JK][1,4]BENZODIAZEPIN 2(1H) ONE; UNCLASSIFIED DRUG;

ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; PRIORITY JOURNAL;

AFFINITY LABELS; AMINO ACID SEQUENCE; AZEPINES; BENZODIAZEPINES; BINDING SITES; DNA MUTATIONAL ANALYSIS; HIV-1; HIV-2; IMIDAZOLES; MOLECULAR SEQUENCE DATA; NEVIRAPINE; PYRIDINES; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE;

EID: 0026052102     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.88.21.9878     Document Type: Article

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