메뉴 건너뛰기




Volumn 12, Issue 10, 1991, Pages 1839-1845

Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

Author keywords

[No Author keywords available]

Indexed keywords

4 BIPHENYLAMINE; ACYLTRANSFERASE; ALPHA NAPHTHOFLAVONE; AROMATIC AMINE; CARCINOGEN; CYTOCHROME P450 ISOENZYME; DNA; HETEROCYCLIC AMINE; MUTAGENIC AGENT;

EID: 0026040316     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/12.10.1839     Document Type: Article
Times cited : (389)

References (65)
  • 1
    • 0020582085 scopus 로고
    • Mutagens-carcinogens in foods
    • Sugimura, T. and Sato, S. (1983) Mutagens-carcinogens in foods. Cancer Res. (1.), 43, 2415s-242ls.
    • (1983) Cancer Res. , vol.43 , pp. 2415-242l
    • Sugimura, T.1    Sato, S.2
  • 3
    • 0023894247 scopus 로고
    • Successful use of short-term tests for academic purposes: Their use in identification of new environmental carcinogens with possible risk for humans
    • Sugimura, T. (1988) Successful use of short-term tests for academic purposes: their use in identification of new environmental carcinogens with possible risk for humans. Mutat. Res., 205, 33-39.
    • (1988) Mutat. Res. , vol.205 , pp. 33-39
    • Sugimura, T.1
  • 5
    • 0021015045 scopus 로고
    • Microsomal activation of 2-amino-3-methylimidazo(4,5-/)quinoline, a pyrolysate of sardine and beef extracts, to a mutagenic intermediate
    • Yamazoe, Y., Shimada, M, Kamataki, T. and Kato, R. (1983) Microsomal activation of 2-amino-3-methylimidazo(4,5-/)quinoline, a pyrolysate of sardine and beef extracts, to a mutagenic intermediate. Cancer Res., 43, 5768-5774.
    • (1983) Cancer Res. , vol.43 , pp. 5768-5774
    • Yamazoe, Y.1    Shimada, M.2    Kamataki, T.3    Kato, R.4
  • 6
    • 3142573401 scopus 로고
    • Metabolic activation of 2-amino-3,8-dimethy!imidazo[4,5-/]quinoxaline by rat liver microsomes and purified cytochrome P-450
    • Yamazoe, Y., Abu-Zeid, M., Manabe, S., Toyama, S. and Kato, R. (1988) Metabolic activation of 2-amino-3,8-dimethy!imidazo[4,5-/]quinoxaline by rat liver microsomes and purified cytochrome P-450. Carcinogenesis, 9. 105-109.
    • (1988) Carcinogenesis , vol.9 , pp. 105-109
    • Yamazoe, Y.1    Abu-Zeid, M.2    Manabe, S.3    Toyama, S.4    Kato, R.5
  • 7
    • 0024552327 scopus 로고
    • Activation of the food derived mutagen 2-amino-l-methyl-6-phenylimidazo(4,5-6 Jpyridine by rabbit and human liver microsomes and purified forms of cytochrome P^f50
    • McManus, M.E., Fehon, J.S., Kmze, M G., Burgess, W.M., Roberts-Thomson, S., Pond, S.M., Stupans, I. and Veronese, M.E (1989) Activation of the food derived mutagen 2-amino-l-methyl-6-phenylimidazo(4,5-6 Jpyridine by rabbit and human liver microsomes and purified forms of cytochrome P^f50. Carcinogenesis, 10, 357-363.
    • (1989) Carcinogenesis , vol.10 , pp. 357-363
    • McManus, M.E.1    Fehon, J.S.2    Kmze, M.G.3    Burgess, W.M.4    Roberts-Thomson, S.5    Pond, S.M.6    Stupans, I.7    Veronese, M.E.8
  • 8
    • 0024365294 scopus 로고
    • Humanliver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens by umu gene response in Salmonella tvphimurium TA 1535/pSK1002
    • Shimada, T., Iwasaki, M., Martin, M.V. and Guengerich, F.P. (1988) Humanliver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens by umu gene response in Salmonella tvphimurium TA 1535/pSK1002. Cancer Res., 46, 3218-3228.
    • (1988) Cancer Res. , vol.46 , pp. 3218-3228
    • Shimada, T.1    Iwasaki, M.2    Martin, M.V.3    Guengerich, F.P.4
  • 9
    • 0022566931 scopus 로고
    • Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates
    • Kato, R. (1986) Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates. CRC Cm. Rev. Toxicol., 16, 307-348.
    • (1986) CRC Cm. Rev. Toxicol. , vol.16 , pp. 307-348
    • Kato, R.1
  • 10
    • 0020644891 scopus 로고
    • Acetylation, deacetylation and acyl transfer. Environ
    • King C M. and Glowinski, I.B. (1983) Acetylation, deacetylation and acyl transfer. Environ. Health Perspect., 49, 43-50.
    • (1983) Health Perspect. , vol.49 , pp. 43-50
    • King, C.M.1    Glowinski, I.B.2
  • 11
    • 0023812845 scopus 로고
    • Acetylalor genotype and arylamine-induced carcinogenesis
    • Hein, D.W. (1988) Acetylalor genotype and arylamine-induced carcinogenesis. Biochim. Biophys. Acta, 948, 37-66.
    • (1988) Biochim. Biophys. Acta , vol.948 , pp. 37-66
    • Hein, D.W.1
  • 13
    • 0023681314 scopus 로고
    • Genotoxic activity of the /V-acetylated metabolites of the food mutagens 2-amino-3-methylimidazo[4,5-/]quinoline (IQ) and 2-amino-3,8-dimethyl-imidazo[4,5-/]quinoline (MelQ)
    • Brunborg, G., Holme, J.A., Alexander, J., Becher, G. and Hongslo, J.K. (1988) Genotoxic activity of the /V-acetylated metabolites of the food mutagens 2-amino-3-methylimidazo[4,5-/]quinoline (IQ) and 2-amino-3,8-dimethyl-imidazo[4,5-/]quinoline (MelQ). Mutagenesis, 1, 303-309.
    • (1988) Mutagenesis , vol.1 , pp. 303-309
    • Brunborg, G.1    Holme, J.A.2    Alexander, J.3    Becher, G.4    Hongslo, J.K.5
  • 14
    • 0021167699 scopus 로고
    • Species differences in the iV-acetylation by liver cytosol of mutagenic heterocyclic aromatic amines in protein pyrolysates
    • Shinohara, A., Yamazoe, Y., Saito, K., Kamataki, T and Kato, R. (1984) Species differences in the iV-acetylation by liver cytosol of mutagenic heterocyclic aromatic amines in protein pyrolysates. Carcinogenesis, 5, 683-686.
    • (1984) Carcinogenesis , vol.5 , pp. 683-686
    • Shinohara, A.1    Yamazoe, Y.2    Saito, K.3    Kamataki, T.4    Kato, R.5
  • 15
    • 0025601471 scopus 로고
    • Purification of hepatic polymorphic A'-acetyltransfcrase from homozygous rapid acetylator inbred hamster: Identity with polymorphic iV-hydroxyarylanunc-O-acetyltransfcrase
    • Trinidad, A., Hein, D W., Rustan, T.D., Ferguson, R.J., Miller, L.S., Bucher, K.D., Kirlin, W.G., Ogolla, F. and Andrews, A. F. (1990) Purification of hepatic polymorphic A'-acetyltransfcrase from homozygous rapid acetylator inbred hamster: identity with polymorphic iV-hydroxyarylanunc-O-acetyltransfcrase. Cancer Res., 50, 7942-7949.
    • (1990) Cancer Res. , vol.50 , pp. 7942-7949
    • Trinidad, A.1    Hein, D.W.2    Rustan, T.D.3    Ferguson, R.J.4    Miller, L.S.5    Bucher, K.D.6    Kirlin, W.G.7    Ogolla, F.8    Andrews, A.F.9
  • 16
    • 0025695732 scopus 로고
    • Monomorphic and polymorphic isozymes of arylamine /V-accty 11ransferases in hamster liver: Purification of the isozymes and genetic basis of V-acetylation
    • Ozawa, S., Abu-Zeid, M., Kawakubo, Y, Toyama, S, Yamazoe, Y. and Kato, R. (1990) Monomorphic and polymorphic isozymes of arylamine /V-accty 11ransferases in hamster liver: purification of the isozymes and genetic basis of V-acetylation. Carcinogenesis, 11, 2137-2144.
    • (1990) Carcinogenesis , vol.11 , pp. 2137-2144
    • Ozawa, S.1    Abu-Zeid, M.2    Kawakubo, Y.3    Toyama, S.4    Yamazoe, Y.5    Kato, R.6
  • 17
    • 0021868587 scopus 로고
    • Hepatic /V-oxidation, acetyl-transfer and DNA-binding of the acetylated metabolites of the carcinogen, benzidine
    • Frederick, C.B., Weis, C.C., Flammang, T.J., Martin, C N. and Kadlubar, F.F. (1985) Hepatic /V-oxidation, acetyl-transfer and DNA-binding of the acetylated metabolites of the carcinogen, benzidine. Carcinogenesis, 6, 959-965.
    • (1985) Carcinogenesis , vol.6 , pp. 959-965
    • Frederick, C.B.1    Weis, C.C.2    Flammang, T.J.3    Martin, C.N.4    Kadlubar, F.F.5
  • 18
    • 0021810037 scopus 로고
    • Catalysis of the covalent binding of 3-hydroxyamino-l-methyl-57/-pyrido4,3-6]indole to DNA by a /-proline-and adneosine triphosphate-dependent enzyme in rat hepatic cytosol
    • Yamazoe, Y., Shimada, M., Shinohara, A., Saito, K., Kamataki, T. and Kato, R. (1985) Catalysis of the covalent binding of 3-hydroxyamino-l-methyl-57/-pyrido4,3-6]indole to DNA by a /-proline-and adneosine triphosphate-dependent enzyme in rat hepatic cytosol. Cancer Res., 45, 2495-2500.
    • (1985) Cancer Res. , vol.45 , pp. 2495-2500
    • Yamazoe, Y.1    Shimada, M.2    Shinohara, A.3    Saito, K.4    Kamataki, T.5    Kato, R.6
  • 19
    • 0021967611 scopus 로고
    • DNA binding of /V-hydroxy-Trp-P-2 and /V-hydroxy-Glu-P-1 by acetyl-CoA dependent enzyme in mammalian liver cytosol
    • Shinohara, A., Saito, K., Yamazoe, Y., Kamataki, T. and Kato, R. (1985) DNA binding of /V-hydroxy-Trp-P-2 and /V-hydroxy-Glu-P-1 by acetyl-CoA dependent enzyme in mammalian liver cytosol. Carcinogenesis, 6, 305-307.
    • (1985) Carcinogenesis , vol.6 , pp. 305-307
    • Shinohara, A.1    Saito, K.2    Yamazoe, Y.3    Kamataki, T.4    Kato, R.5
  • 20
    • 0022735180 scopus 로고
    • Acetyl coenzyme A-dependent metabolic activation of A/-hydroxy-3,2'-dimethyl-4-aminobiphenyl and several carcinogenic /V-hydroxy arylamines in relation to tissue and species differences, other acyl donors, and arylhydroxamic acid-dependent acyltransferases
    • Flammang, T.J. and Kadlubar, F.F. (1986) Acetyl coenzyme A-dependent metabolic activation of A/-hydroxy-3,2'-dimethyl-4-aminobiphenyl and several carcinogenic /V-hydroxy arylamines in relation to tissue and species differences, other acyl donors, and arylhydroxamic acid-dependent acyltransferases. Carcinogenesis, 7, 919-926.
    • (1986) Carcinogenesis , vol.7 , pp. 919-926
    • Flammang, T.J.1    Kadlubar, F.F.2
  • 21
    • 0017686069 scopus 로고
    • Isolation of the glucuronic acid conjugate of /V-hydroxy-l-aminobiphenyl from dog urine and its mutagenic activity
    • Radomski, J.L., Heam, W.L., Radomski, T., Moreno, H and Scott, W.E (1977) Isolation of the glucuronic acid conjugate of /V-hydroxy-l-aminobiphenyl from dog urine and its mutagenic activity. Cancer Res., 37, 1757-1762.
    • (1977) Cancer Res. , vol.37 , pp. 1757-1762
    • Radomski, J.L.1    Heam, W.L.2    Radomski, T.3    Moreno, H.4    Scott, W.E.5
  • 22
    • 0017365046 scopus 로고
    • Hepatic microsomal /V-glucuronidation and nucleic acid binding of /V-hydroxyarylamines in relation to urinary bladder carcinogenesis
    • Kadlubar, F.F., Miller, J.A. and Miller, E.C. (1977) Hepatic microsomal /V-glucuronidation and nucleic acid binding of /V-hydroxyarylamines in relation to urinary bladder carcinogenesis. Cancer Res, 37, 805-814.
    • (1977) Cancer Res , vol.37 , pp. 805-814
    • Kadlubar, F.F.1    Miller, J.A.2    Miller, E.C.3
  • 23
    • 0019511348 scopus 로고
    • Alteration of urinary levels of the carcinogen, /V-hydroxy-2-naphthylamine, and its iV-glucuronide in the rat by control of urinary pH, inhibition of metabolic sulfation, and changes in biliary excretion
    • Kadlubar, F.F., Unruh, L.E., Flammang, T.J., Sparks, D., Mitchum, R.K. and Mulder, G.J. (1981) Alteration of urinary levels of the carcinogen, /V-hydroxy-2-naphthylamine, and its iV-glucuronide in the rat by control of urinary pH, inhibition of metabolic sulfation, and changes in biliary excretion. Otenr-Biol. Imeractions, 33, 129-147.
    • (1981) Otenr-Biol. Imeractions , vol.33 , pp. 129-147
    • Kadlubar, F.F.1    Unruh, L.E.2    Flammang, T.J.3    Sparks, D.4    Mitchum, R.K.5    Mulder, G.J.6
  • 24
    • 0026002985 scopus 로고
    • The frequency of urination and its effects on metabolism, pharmacokinetics, blood hemoglobin adduct formation, and liver and urinary bladder DNA adduct formation in beagle dogs administered the carcinogen, 4-aminobiphenyl
    • Kadlubar, F.F., Dooley, K.L., Teitel, C.H., Roberts, D.W., Benson, R.W., Butler, M.A., Bailey, J.R., Young, J.F., Skipper, P.L. and Tannenbaum, S.R. (1991) The frequency of urination and its effects on metabolism, pharmacokinetics, blood hemoglobin adduct formation, and liver and urinary bladder DNA adduct formation in beagle dogs administered the carcinogen, 4-aminobiphenyl. Cancer Res, 51, 4371-4377.
    • (1991) Cancer Res , vol.51 , pp. 4371-4377
    • Kadlubar, F.F.1    Dooley, K.L.2    Teitel, C.H.3    Roberts, D.W.4    Benson, R.W.5    Butler, M.A.6    Bailey, J.R.7    Young, J.F.8    Skipper, P.L.9    Tannenbaum, S.R.10
  • 25
    • 0024500474 scopus 로고
    • Polymorphic expression of acetyl coenzyme A-dependent arylamine A'-acetyltransferase and acetyl coenzyme A-dependent O-acetyltransferase-mediated activation of A'-hydroxyarylamines by human bladder cytosol
    • Kirlin, W.G., Trinidad, A., Yerokun, T., Ogolla, F., Ferguson, R.J., Andrews, A.F., Brady, P.K. and Hein, D.W. (1989) Polymorphic expression of acetyl coenzyme A-dependent arylamine A'-acetyltransferase and acetyl coenzyme A-dependent O-acetyltransferase-mediated activation of A'-hydroxyarylamines by human bladder cytosol. Cancer Res., 49, 2448-2454.
    • (1989) Cancer Res. , vol.49 , pp. 2448-2454
    • Kirlin, W.G.1    Trinidad, A.2    Yerokun, T.3    Ogolla, F.4    Ferguson, R.J.5    Rews, A.F.6    Brady, P.K.7    Hein, D.W.8
  • 26
    • 0024538978 scopus 로고
    • Arachkkmic acid-dependent peroxidative activation carcinogenic arylamines by extrahepatic human tissue microsomes
    • Flammang, T.J., Yamazoe, Y., Benson, R.W., Roberts, D.W., Potter, D.W., Chu, D.ZJ, Lang, N.P. and Kadlubar, F.F. (1989) Arachkkmic acid-dependent peroxidative activation carcinogenic arylamines by extrahepatic human tissue microsomes. Cancer Res., 49, 1977-1982.
    • (1989) Cancer Res , vol.49 , pp. 1977-1982
    • Flammang, T.J.1    Yamazoe, Y.2    Benson, R.W.3    Roberts, D.W.4    Potter, D.W.5    Chu, D.6    Lang, N.P.7    Kadlubar, F.F.8
  • 27
    • 0022922601 scopus 로고
    • The role of acetylator phenotype on hepatic and extrahepatic acetylation, deacetylation, and sulfation of 2-aminofluorene. 2-acetylaminofluorene. and A'-hydroxy-2-acetylaminofluorene in the inbred hamster
    • Hein, D.W., Kirlin, W.G., Ogolla, F., Trinidad, A., Thompson, L.K. and Ferguson, R.J. (1986) The role of acetylator phenotype on hepatic and extrahepatic acetylation, deacetylation, and sulfation of 2-aminofluorene. 2-acetylaminofluorene. and A'-hydroxy-2-acetylaminofluorene in the inbred hamster. Drug Metab. Disp., 14, 566-573.
    • (1986) Drug Metab. Disp. , vol.14 , pp. 566-573
    • Hein, D.W.1    Kirlin, W.G.2    Ogolla, F.3    Trinidad Thompson, A.L.K.4    Ferguson, R.J.5
  • 28
    • 84944370562 scopus 로고
    • Role of aromatic amine acetyltransferase in human colorectal cancer. Arch
    • Lang, N.P., Chu, D.Z.J., Hunter, C.F., Kendall, D.C., Flammang, T.J. and Kadlubar, F.F. (1986) Role of aromatic amine acetyltransferase in human colorectal cancer. Arch. Surg., 121, 1259-1261.
    • (1986) Surg. , vol.121 , pp. 1259-1261
    • Lang, N.P.1    Chu, D.Z.J.2    Hunter, C.F.3    Kendall, D.C.4    Flammang, T.J.5    Kadlubar, F.F.6
  • 30
    • 0021931373 scopus 로고
    • A'-Acetyltransferase phenotypes in the urinary bladder carcinogenesis of a low-risk population
    • Mommsen, D., Barfod, N.M. and Aagaard, J (1985) A'-Acetyltransferase phenotypes in the urinary bladder carcinogenesis of a low-risk population. Carcinogenesis, 6, 199-201.
    • (1985) Carcinogenesis , vol.6 , pp. 199-201
    • Mommsen, D.1    Barfod, N.M.2    Aagaard, J.3
  • 32
    • 0024235283 scopus 로고
    • Genetic polymorphism and cancer susceptibility: Evidenceconcerning acetyltransferases and cancer of the urinary bladder
    • Hein, D.W (1988) Genetic polymorphism and cancer susceptibility: evidenceconcerning acetyltransferases and cancer of the urinary bladder. Bioessavs, 9, 200-204.
    • (1988) Bioessavs , vol.9 , pp. 200-204
    • Hein, D.W.1
  • 34
    • 0020420450 scopus 로고
    • ModificaUon of DNA with potent mutacarcinogenic 2-amino-6-methyldipyrido[1,2-ti:3',2’-7]imidazole isolated from a glutamic acid pyrolysate: Structure of the nucleic acid base and initial chemical event caused by the mutagen
    • Hashimoto, Y., Shudo, K. and Okamoto, T. (1982) ModificaUon of DNA with potent mutacarcinogenic 2-amino-6-methyldipyrido[1,2-ti:3',2’-7]imidazole isolated from a glutamic acid pyrolysate: structure of the nucleic acid base and initial chemical event caused by the mutagen. J. Am. Chem. Soc., 104, 7636-7640
    • (1982) J Am Chem Soc , vol.104 , pp. 7636-7640
    • Hashimoto, Y.1    Shudo, K.2    Okamoto, T.3
  • 35
    • 0002656344 scopus 로고
    • Synthesis of 3.8-dimethyl-2-nitro-3//-imidazo[4,5-/]-quinoxaline.the 2-nitro analogue of the food carcinogen MelQx
    • Grivas, S. (1988) Synthesis of 3.8-dimethyl-2-nitro-3//-imidazo[4,5-/]-quinoxaline.the 2-nitro analogue of the food carcinogen MelQx. J. Chem. Res. (8) 84.
    • (1988) J. Chem. Res , Issue.8 , pp. 84
    • Grivas, S.1
  • 36
    • 0014418506 scopus 로고
    • Reactivity of the diacetyl derivative of the carcinogen 4-hydroxyaminoquinoline-l-oxide with DNA, RNA and other nucleophiles
    • Enomoto, M., Sato, K., Miller, E.C. and Miller, J. A. (1968) Reactivity of the diacetyl derivative of the carcinogen 4-hydroxyaminoquinoline-l-oxide with DNA, RNA and other nucleophiles. Life Sci., 7, 1025-1032.
    • (1968) Life Sci. , vol.7 , pp. 1025-1032
    • Enomoto, M.1    Sato, K.2    Miller, E.C.3    Miller, J.A.4
  • 37
    • 0019459161 scopus 로고
    • A rapid and simple synthesis of reactive metabolites of carcinogenic aromatic amines in high yield
    • Westra, J.G. (1981) A rapid and simple synthesis of reactive metabolites of carcinogenic aromatic amines in high yield. Carcinogenesis, 2, 355-357.
    • (1981) Carcinogenesis , vol.2 , pp. 355-357
    • Westra, J.G.1
  • 38
    • 84943093374 scopus 로고
    • Uberdie reduktion von nitroverbindungen nach der methode von Zinin
    • Willstatter, R. and Kubli, H. (1908) Uberdie reduktion von nitroverbindungen nach der methode von Zinin. Chem. Ber., 41, 1936-1940.
    • (1908) Chem. Ber. , vol.41 , pp. 1936-1940
    • Willstatter, R.1    Kubli, H.2
  • 39
    • 0024343858 scopus 로고
    • Human cytochrome P-450pa (P-450IA2), the phenacetin O-deethylase, is primarily responsible for Lie hepatic 3-demethylation of caffeine and A'-oxidation of carcinogenic arylamines
    • Butler, M.A., Iwasaki, M., Guengerich, F.P. and Kadlubar, F.F. (1989) Human cytochrome P-450pa (P-450IA2), the phenacetin O-deethylase, is primarily responsible for Lie hepatic 3-demethylation of caffeine and A'-oxidation of carcinogenic arylamines. Proc Natl. Acad. Set. USA, 86, 7696-7700.
    • (1989) Proc Natl. Acad. Set. USA , vol.86 , pp. 7696-7700
    • Butler, M.A.1    Iwasaki, M.2    Guengerich, F.P.3    Kadlubar, F.F.4
  • 40
    • 0001818451 scopus 로고
    • Microsomal enzymes involved in toxicology-analysis and separation
    • Hayes, A. W. (ed.), Raven Press, New York
    • Guengerich, F.P (1982) Microsomal enzymes involved in toxicology-analysis and separation. In Hayes, A. W. (ed.), Principles and Methods of Toxicology. Raven Press, New York, pp. 609-634.
    • (1982) Principles and Methods of Toxicology , pp. 609-634
    • Guengerich, F.P.1
  • 41
    • 0023641072 scopus 로고
    • The S-acetyl coenzyme A-dependent metabolic activation of the carcinogen A'-hydroxy-2-aminofluorene by human liver cytosol and its relationship to the aromatic amine A'-acetyltransferase phenotype
    • Flammang, T.J., Yamazoe, Y., Guengerich, F.P. and Kadlubar, F.F. (1987) The S-acetyl coenzyme A-dependent metabolic activation of the carcinogen A'-hydroxy-2-aminofluorene by human liver cytosol and its relationship to the aromatic amine A'-acetyltransferase phenotype. Carcinogenesis, 8, 1967-1970.
    • (1987) Carcinogenesis , vol.8 , pp. 1967-1970
    • Flammang, T.J.1    Yamazoe, Y.2    Guengerich, F.P.3    Kadlubar, F.F.4
  • 42
    • 0019753774 scopus 로고
    • A'-Acetyltransferase and arylhydroxamic acid acyltransferase
    • Weber, W. and King, C.M. (1981) A'-Acetyltransferase and arylhydroxamic acid acyltransferase. Methods Enzymol., 77, 272-280.
    • (1981) Methods Enzymol. , vol.77 , pp. 272-280
    • Weber, W.1    King, C.M.2
  • 43
    • 0024453380 scopus 로고
    • Enzymatic acetylation and sulfation of A'-hydroxyarylamines in bacteria and rat livers
    • Yamazoe, Y., Abu-Zeid, M., Gong, D., Staiano, N. and Kato, R. (1989) Enzymatic acetylation and sulfation of A'-hydroxyarylamines in bacteria and rat livers. Carcinogenesis, 10, 1675-1679.
    • (1989) Carcinogenesis , vol.10 , pp. 1675-1679
    • Yamazoe, Y.1    Abu-Zeid, M.2    Gong, D.3    Staiano, N.4    Kato, R.5
  • 45
    • 0025921619 scopus 로고
    • 32P-Postlabelling analysis of urinary mutagens from smokers of black tobacco implicates 2-amino-l-mcthyl-6-phenylimidazo(4,5-6]pyridinc (PhIP) as a major DNA-damaging agent
    • Peluso, M., Castegnaro, M., Malavielle, C., Friesen, M., Garren, L., Hautefeuille, A., Vineis, P., Kadlubar, F. and Bartsch, H. (1991) 32P-Postlabelling analysis of urinary mutagens from smokers of black tobacco implicates 2-amino-l-mcthyl-6-phenylimidazo(4,5-6]pyridinc (PhIP) as a major DNA-damaging agent. Carcinogenesis, 12, 713-717.
    • (1991) Carcinogenesis , vol.12 , pp. 713-717
    • Peluso, M.1    Castegnaro, M.2    Malavielle, C.3    Friesen, M.4    Garren, L.5    Hautefeuille, A.6    Vineis, P.7    Kadlubar, F.8    Bartsch, H.9
  • 46
    • 0018657507 scopus 로고
    • The primary aromatic amines: Their biological properties and structure-activity relationships
    • Radomski, J.L. (1979) The primary aromatic amines: their biological properties and structure-activity relationships. Anna. Rev. Pharmacol. Toxicol., 19. 129-157.
    • (1979) Anna. Rev. Pharmacol. Toxicol. , vol.19 , pp. 129-157
    • Radomski, J.L.1
  • 47
    • 0025237412 scopus 로고
    • Cloning and expression of cDNAs for polymorphic and monomorphic arylamine A'-acetyltransferase from human liver
    • Ohsako, S. and Deguchi, T. (1990) Cloning and expression of cDNAs for polymorphic and monomorphic arylamine A'-acetyltransferase from human liver. J. Biol. Chem., 265, 4630-4634.
    • (1990) J. Biol. Chem. , vol.265 , pp. 4630-4634
    • Ohsako, S.1    Deguchi, T.2
  • 49
    • 0020644905 scopus 로고
    • In ano metabolites of 3,2'-dimethyl-4-aminobiphenyl (DMABP) bearing on its organotropism in the Syrian golden hamster and the F344 rat. Environ
    • Nussbaum, M., Fiala, E.S., Kulkami, B., El-Bayoumy, K. and Weisburger, J.H. (1983) In ano metabolites of 3,2'-dimethyl-4-aminobiphenyl (DMABP) bearing on its organotropism in the Syrian golden hamster and the F344 rat. Environ. Health Pcrspect., 49, 223-231.
    • (1983) Health Pcrspect. , vol.49 , pp. 223-231
    • Nussbaum, M.1    Fiala, E.S.2    Kulkami, B.3    El-Bayoumy, K.4    Weisburger, J.H.5
  • 50
    • 0025251678 scopus 로고
    • The contribution of A'-oxidation to the metabolism of the food-borne carcinogen 2-amino-3,8-dimethylirrudazo(4,5-/]quinoxaline in rat hepatocytes
    • Turesky, R.J., Bracco-Hammer, I., Markovic, J., Richli, U., Kappeler, A.-M. and Welti, D.H. (1990) The contribution of A'-oxidation to the metabolism of the food-borne carcinogen 2-amino-3,8-dimethylirrudazo(4,5-/]quinoxaline in rat hepatocytes. Chem. Res. Toxicol., 3, 524-535.
    • (1990) Chem. Res. Toxicol. , vol.3 , pp. 524-535
    • Turesky, R.J.1    Bracco-Hammer, I.2    Markovic, J.3    Richli Kappeler, U.A.-M.4    Welti, D.H.5
  • 51
    • 0002488834 scopus 로고
    • Metabolic fate of heterocyclic amines
    • Hayatsu, H. (ed.), CRC Press, Boca Raton, FL
    • Alexander, J.A. and Wallin, H. (1991) Metabolic fate of heterocyclic amines. In Hayatsu, H. (ed.), Mutagens in Food: Detection and Prevention. CRC Press, Boca Raton, FL, pp. 143-156.
    • (1991) Mutagens in Food Detection and Prevention , pp. 143-156
    • Alexander, J.A.1    Wallin, H.2
  • 52
    • 0022267040 scopus 로고
    • Chemical properties of ultimate carcinogenic metabolites of arylamines and arylamides
    • Harvey, R.G. (ed.), American Chemical Society, Washington, DC
    • Kadlubar, F.F. and Beland, F.A. (1985) Chemical properties of ultimate carcinogenic metabolites of arylamines and arylamides. In Harvey, R.G. (ed.). Polycyclic Hydrocarbons and Carcinogenesis. ACS Symposium Series 283. American Chemical Society, Washington, DC, pp. 331-370.
    • (1985) Polycyclic Hydrocarbons and Carcinogenesis. ACS Symposium Series , vol.283 , pp. 331-370
    • Kadlubar, F.F.1    Beland, F.A.2
  • 53
    • 0023883437 scopus 로고
    • Reaction of A'-hydroxylamine and A'-acetoxy derivatives of 2-amino-3-methylimidazo(4,5-/]quinoline with DNA. Synthesis and identification of A'-(deoxyguanosine-8-yl)-[Q
    • Snyderwine, E.G., Roller, P.R., Adamson, R.H., Sato, S. and Thotgeirsson, S.S. (1988) Reaction of A'-hydroxylamine and A'-acetoxy derivatives of 2-amino-3-methylimidazo(4,5-/]quinoline with DNA. Synthesis and identification of A'-(deoxyguanosine-8-yl)-[Q. Carcinogenesis, 9, 1061-1065.
    • (1988) Carcinogenesis , vol.9 , pp. 1061-1065
    • Snyderwine, E.G.1    Roller, P.R.2    Adamson, R.H.3    Sato, S.4    Thotgeirsson, S.S.5
  • 54
    • 0017653199 scopus 로고
    • Phenol sulphotransferase and undine diphosphate glucuronyltransferase from rat liver in vivo and in vitro
    • Mulder, G.J. and Scholtens, E. (1977) Phenol sulphotransferase and undine diphosphate glucuronyltransferase from rat liver in vivo and in vitro. Biochem. J., 165, 553-559
    • (1977) Biochem. J. , vol.165 , pp. 553-559
    • Mulder, G.J.1    Scholtens, E.2
  • 55
    • 0024490721 scopus 로고
    • Nucleic acid binding and mutagenicity of 2-amino-3,8-dimethylimidazo[4,5-/]quinoxaline
    • Negishi, C., Yamaizumi, Z. and Sato, S. (1989) Nucleic acid binding and mutagenicity of 2-amino-3,8-dimethylimidazo[4,5-/]quinoxaline. Mutat. Res., 210, 127-134
    • (1989) Mutat. Res. , vol.210 , pp. 127-134
    • Negishi, C.1    Yamaizumi, Z.2    Sato, S.3
  • 56
    • 0023110788 scopus 로고
    • Activation of 2-amino-3-methyl-unidazo[4,5-/]quinoline in rat and human hepatocyte/Salmonella mutagenicity assays: The contnbution of hepatic conjugation
    • Paterson, P. and Chipman, J.K. (1987) Activation of 2-amino-3-methyl-unidazo[4,5-/]quinoline in rat and human hepatocyte/Salmonella mutagenicity assays: the contnbution of hepatic conjugation. Mutagenesis, 2, 137-140
    • (1987) Mutagenesis , vol.2 , pp. 137-140
    • Paterson, P.1    Chipman, J.K.2
  • 57
    • 0021871782 scopus 로고
    • Metabolic activation of mutagenic A'-hydroxyarylamines by O-acetyltransferase in Salmonella typhimurium TA98. Arch. Biochem
    • Saito, K, Shinohara, A., Kamataki, T. and Kalo, R. (1985) Metabolic activation of mutagenic A'-hydroxyarylamines by O-acetyltransferase in Salmonella typhimurium TA98. Arch. Biochem. Biophys., 239, 286-295.
    • (1985) Biophys. , vol.239 , pp. 286-295
    • Saito, K.1    Shinohara, A.2    Kamataki, T.3    Kalo, R.4
  • 58
    • 0020955270 scopus 로고
    • Ultimate forms of mutagenic and carcinogenic heterocyclic amines produced by pyrolysis. Biochem. Biophys. Res
    • Nagao, M., Fujita, Y., Wakabayashi, K. and Sugimura, T. (1983) Ultimate forms of mutagenic and carcinogenic heterocyclic amines produced by pyrolysis. Biochem. Biophys. Res. Commun., 114, 626-631.
    • (1983) Commun. , vol.114 , pp. 626-631
    • Nagao, M.1    Fujita, Y.2    Wakabayashi, K.3    Sugimura, T.4
  • 59
    • 0024379776 scopus 로고
    • Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-6]pyridinc (PhIP): Formation of 2-hydroxyamino-PhIP, a directly acting genotoxic metabolite
    • Holme, J.A., Wallin, H., Brunborg, G., Soderlund, E., Hongslo, J.K. and Alexander, J. (1989) Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-6]pyridinc (PhIP): formation of 2-hydroxyamino-PhIP, a directly acting genotoxic metabolite. Carcinogenesis, 10, 1389-1396.
    • (1989) Carcinogenesis , vol.10 , pp. 1389-1396
    • Holme, J.A.1    Wallin, H.2    Brunborg, G.3    Soderlund, E.4    Hongslo, J.K.5    Alexander, J.6
  • 60
    • 0022727089 scopus 로고
    • A'-Hydroxyarylamine O-acetyltransferase in hamster liver, identity with arylhydroxamic acid, A', O-acetyltransferase and arylamine A'-acetyltransferase
    • Saito, K., Shinohara, A., Kamataki, T. and Kato, R. (1986) A'-Hydroxyarylamine O-acetyltransferase in hamster liver, identity with arylhydroxamic acid, A', O-acetyltransferase and arylamine A'-acetyltransferase. J. Biochem., 99, 1689-1697.
    • (1986) J. Biochem. , vol.99 , pp. 1689-1697
    • Saito, K.1    Shinohara, A.2    Kamataki, T.3    Kato, R.4
  • 61
    • 0023640953 scopus 로고
    • Acetylator genotype-dependent metabolic activation of carcinogenic A'-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: Relationship to arylamine A'-acetyltransferase
    • Hein, D.W., Flammang TJ., Kirlin, W.G., Trinidad, A. and Ogolla, F. (1987) Acetylator genotype-dependent metabolic activation of carcinogenic A'-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine A'-acetyltransferase. Carcinogenesis, 8, 1767-1774.
    • (1987) Carcinogenesis , vol.8 , pp. 1767-1774
    • Hein, D.W.1    Flammang, T.J.2    Kirlin, W.G.3    Trinidad, A.4    Ogolla, F.5
  • 62
    • 0022484387 scopus 로고
    • Acetyl coenzyme A dependent activation of A'-hydroxy derivatives of carcinogenic arylamines: Mechanisms of activation, species difference, tissue distribution, and acetyl donor specificity
    • Shinohara, A., Saito, K., Yamazoe, Y., Kamataki, T. and Kato, R. (1986) Acetyl coenzyme A dependent activation of A'-hydroxy derivatives of carcinogenic arylamines: mechanisms of activation, species difference, tissue distribution, and acetyl donor specificity. Cancer Res., 46, 4362-4367.
    • (1986) Cancer Res. , vol.46 , pp. 4362-4367
    • Shinohara, A.1    Saito, K.2    Yamazoe, Y.3    Kamataki, T.4    Kato, R.5
  • 63
    • 0025013470 scopus 로고
    • Role of sulfation and acetylation in the activation of 2-hydroxyamino-l-methyl-6-phenylimidazo[4,5-6]pyridine to intermediates which bind to DNA
    • Buonarati, M.H., Turteltaub, K.W., Shen, N.H. and Felton, J.S. (1990) Role of sulfation and acetylation in the activation of 2-hydroxyamino-l-methyl-6-phenylimidazo[4,5-6]pyridine to intermediates which bind to DNA. Mutat. Res., 245, 185-190.
    • (1990) Mutat. Res. , vol.245 , pp. 185-190
    • Buonarati, M.H.1    Turteltaub, K.W.2    Shen, N.H.3    Felton, J.S.4
  • 64
    • 0025739671 scopus 로고
    • Distribution of acetyltransferase activities in the intestines of rapid and slow acetylator rabbits
    • Ilett, K.F., Reeves, P.T., Minchin, R.F., Kinnear, B.F., Watson, H.F. and Kadlubar, F.F (1991) Distribution of acetyltransferase activities in the intestines of rapid and slow acetylator rabbits Carcinogenesis, 12. 1465-1469.
    • (1991) Carcinogenesis , vol.12 , pp. 1465-1469
    • Ilett, K.F.1    Reeves, P.T.2    Minchin, R.F.3    Kinnear, B.F.4    Watson, H.F.5    Kadlubar, F.F.6
  • 65
    • 0025962119 scopus 로고
    • Acetylator genotype-dependent expression of arylamine A'-acetyltransferase in human colon cytosol from non-cancer and colorectal cancer patients
    • Kirlin, W.G., Ogolla, F., Andrews, A.F., Trinidad, A., Ferguson, R.J., Yerokun, T., Mpezo, M. and Hein, D.W. (1991) Acetylator genotype-dependent expression of arylamine A'-acetyltransferase in human colon cytosol from non-cancer and colorectal cancer patients. Cancer Res., 51, 549-555.
    • (1991) Cancer Res. , vol.51 , pp. 549-555
    • Kirlin, W.G.1    Ogolla, F.2    Rews, A.F.3    Trinidad, A.4    Ferguson Yerokun, R.J.T.5    Mpezo, M.6    Hein, D.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.