Modulation of lymphocyte functions and immune responses by cysteine and cysteine derivatives

The American Journal of Medicine

Volumn 91, Issue 3 SUPPL. 3, 1991, Pages

  Dröge, Wulf ^a   Eck, H P ^a   Gmunder H ^a   Mihm, S ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CYSTEINE; CYSTINE; GLUTATHIONE;

CELL MEMBRANE TRANSPORT; CONFERENCE PAPER; DRUG EFFECT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; LYMPHOCYTE FUNCTION; MODULATION; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMAL; CYSTEINE; CYSTINE; GENE EXPRESSION; HIV INFECTIONS; HUMAN; LYMPHOCYTES; MODELS, BIOLOGICAL;

EID: 0026038764     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/0002-9343(91)90297-B     Document Type: Article

References (20)

1. Macrophages regulate intracellular glutathione levels of lymphocytes
2. Plasma glutamate concentration and lymphocyte activity
3. Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1 infected patients
4. Low membrane transport activity for cystine in resting and mitogenically stimulated human lymphocyte preparations and human T-cell clones
5. Transmission of signals from the T lymphocyte antigen receptor to the genes 18 responsible for cell proliferation and immune function the missing link
6. HTLV-1 transactivator induces interleukin-2 receptor expression through an NFκB-like factor
7. Functionally distinct NFκB binding sites in the immunoglobulin κ and IL-2 receptor α chain genes
8. Tumor necrosis factor β induces proteins that bind specifically to kB-like enhancer elements and regulate interleukin 2 receptor α-chain gene expression in primary human T lymphocytes
9. Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-1 tax gene product
10. A monoclonal antibody (ANTI-Tac) reactive with activated and functionally mature human T cells
11. Interleukin 2 receptor gene expression in normal human T lymphocytes
12. Intracellular glutathione level controls DNA-binding activity of NFκB-like proteins
13. Inhibition of HIV-1 replication and NFκB activity by cysteine and cysteine derivatives
14. Regulation of T-cell activation and T-cell growth factor (TCGF) production by hydrogen peroxide
15. Regulation of interleukin-2 production interleukin-2 mRNA expression and intracellular glutathione levels in ex vivo derived T lymphocytes by lactate
16. Interleukin-2 mRNA expression, lymphokine production and DNA synthesis in glutathione-depleted T cells
17. Influence of the extracellular glutamate concentration on the intracellular cyst(e)ine concentration in macrophages and on the capacity to release cysteine
18. Abnormal amino acid concentrations in the blood of patients with acquired immunodeficiency syndrome (AIDS) may contribute to the immunological defect
19. MAC251 infection in rhesus macaques (Macaca mulatta)