Lipoxygenase-mediated secretory effect of canatoxin the toxic protein from Canavalia ensiformis seeds

Toxicon

Volumn 29, Issue 4-5, 1991, Pages 453-459

  Barja Fidalgo, Christina ^a   Guimarães, Jorge A ^b   Carlini, Celia R ^b  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CANATOXIN; ESCULETIN; INDOMETACIN; NORDIHYDROGUAIARETIC ACID; TOXIN;

ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; FEMALE; INSULIN RELEASE; NONHUMAN; PLANT SEED; RABBIT; RAT; SEROTONIN RELEASE; THROMBOCYTE;

ANIMAL; BLOOD PLATELETS; FABACEAE; FEMALE; IN VITRO; INDOMETHACIN; INSULIN; ISLETS OF LANGERHANS; LECTINS; LIPOXYGENASE; LIPOXYGENASE INHIBITORS; NORDIHYDROGUAIARETIC ACID; PLANTS, MEDICINAL; RABBITS; RATS; SECRETORY RATE; SEROTONIN; SUPPORT, NON-U.S. GOV'T; SYNAPTOSOMES; TOXINS; UMBELLIFERONES;

ANIMALIA; CANAVALIA ENSIFORMIS; ORYCTOLAGUS CUNICULUS;

EID: 0026026317     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/0041-0101(91)90019-N     Document Type: Article

References (24)

1. The secretory effect of canatoxin on rat brain synaptosomes involves a lipoxygenase-mediated pathway
2. Isolation and characterization of a toxic protein from Canavalia ensiformis (jack beans) seeds, distinct from concanavalin A
3. Central nervous effect of the convulsant protein canatoxin
4. Platelet release reaction and aggregation induced by canatoxin, a convulsant protein: evidence for the involvement of the platelet lipoxygenase pathway
5. Involvement of lipoxygenase and cyclo-oxygenase pathways in hypoxia and metabolic alkalosis produced by canatoxin in rats
6. Platelets as model for neurons?
7. 4 and by lipoxygenases intermediates
8. A subcellular fractionation approach for studying insulin release mechanisms and calcium metabolism in islets of Langerhans
9. Glucose increases the synthesis of lipoxygenase-mediated metabolites of arachidonic acid in intact rat islets
10. Ether-linked lysophospholipids initiate insulin secretion
11. Lipoxygenase pathway in islets endocrine cells
12. Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerular cells
13. Mechanism of action of gonadotropin-releasing hormone: role of lipoxygenase products of arachidonic acid in luteinizing hormone release
14. Lipoxygenase products modulate histamine release in human basophils
15. Lipoxygenase metabolities of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells
16. Platelets as models: use and limitations
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18. Effects of canatoxin on the circulating levels of gonadotropins and prolactin in rats
19. Convulsions induced by canatoxin in rats are probably a consequence of hypoxia
20. Selective inhibition of platelet lipoxygenase by esculetin
21. Neurotransmitter receptors mediated cyclic GMP formation by involvement of arachidonic acid and lipoxygenase
22. HETEs
23. 2+ in glucose-induced insulin secretion by pancreatic islets
24. Lipoxygenase inhibitors and cyclic AMP-mediated insulin secretion caused by forskolin, theophilline and dibutyryl cyclic AMP