Blood-brain barrier damage in acute multiple sclerosis plaques: An immunocytological study

Brain

Volumn 114, Issue 1, 1991, Pages 557-572

  Gay, D ^a,b   Esiri, M ^a,b  

^a East Suffolk and North Essex Foundation Trust   (United Kingdom)

^b RADCLIFFE INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MACROPHAGE; MALE; MULTIPLE SCLEROSIS; PLAQUE FORMING CELL; PRIORITY JOURNAL;

ACUTE DISEASE; ADOLESCENT; ADULT; BLOOD PROTEINS; BLOOD-BRAIN BARRIER; BRAIN; CAPILLARIES; COMPLEMENT; CYTOLOGICAL TECHNIQUES; FEMALE; HUMAN; IMMUNOGLOBULINS; IMMUNOLOGIC TECHNIQUES; MALE; MIDDLE AGE; MULTIPLE SCLEROSIS; SUPPORT, NON-U.S. GOV'T;

EID: 0026013693     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/114.1.557     Document Type: Article

References (28)

1. Adams CWM (1989) Vascular aspects of multiple sclerosis. In: A Colour Atlas of Multiple Sclerosis and Other Myelin Disorders. Edited by C. W. M. Adams. London: Wolfe Medical, pp. 184-187
2. Adams CWM, Poston RN, Buk SJ (1990) The pathology, histochemistry and immunocytochemistry of lesions in acute multiple sclerosis. Journal of the Neurological Sciences, 92, 291-306
3. Barnes D, McDonald WI, Johnson G, Tofts PS, Landon DN (1987) Quantitative nuclear magnetic resonance imaging: characterisation of experimental cerebral oedema. Journal of Neurology, Neurosurgery and Psychiatry, 50, 125- 133
4. Brown WJ (1978) The capillaries in acute and subacute multiple sclerosis plaques: a morphometric analysis. Neurology, New York, 28, Supplement, 84-92
5. Compston DAS, Morgan BP, Campbell AK, Wilkins P, Cole G, Thomas ND et al. (1989) Immunocytochemical localization of the terminal complement complex in multiple sclerosis. Neuropathology and Applied Neurobiology, 15, 307- 316
6. Coyle P (1987) Analysis of immune complexes in multiple sclerosis. In: Cellular and Humoral Immunological Components of Cerebrospinal Fluid in Multiple Sclerosis. Edited by A. Lowenthal and J. Raus. New York and London: Plenum Press, pp. 129-137
7. Davey FR, Cordell JL, Erber WN, Pulford KAF, Gatter KC, Mason DY (1988) Monoclonal antibody (Y1/82A) with specificity towards peripheral blood monocytes and tissue macrophages. Journal of Clinical Pathology, 41, 753- 758
8. Dawson JW (1916) The histology of disseminated sclerosis. Transactions of the Royal Society of Edinburgh, 50, 517-740
9. Esiri MM, Oppenheimer DR, Brownell B, Haire M (1982) Distribution of measles antigen and immunoglobulin-containing cells in the CNS in subacute sclerosing panencephalitis (SSPE) and atypical measles encephalitis. Journal of the Neurological Sciences, 53, 29-43
10. Esiri MM, Reading MC (1987) Macrophage populations associated with multiple sclerosis plaques. Neuropathology and Applied Neurobiology, 13, 451-465
11. Esiri MM, Reading MC, Squier MV, Hughes JT (1989) Immunocytochemical characterization of the macrophage and lymphocyte infiltrate in the brain in six cases of human encephalitis of varied aetiology. Neuropathology and Applied Neurobiology, 15, 289-305
12. Essner E, Lin W-L (1988) Immunocytochemical localization of laminin, type IV collagen and fibronectin in rat retinal vessels. Experimental Eye Research, 47, 317-327
13. Frankun WA, Mason DY, Pulford K, Fauni B, Buss E, Gatter KC et al. (1986) Immunohistological analysis of human mononuclear phagocytes and dendritic cells by using monoclonal antibodies. Laboratory Investigation, 54, 322- 335
14. Grossman RI, Braffman BH, Brorson JR, Goldberg HI, Silberberg DH, Gonzalez-Scarano F (1988) Multiple sclerosis: serial study of gadolinium-enhanced MR imaging. Radiology, 169, 117- 122
15. Hays AP, Lee SSL, Latov N (1988) Immune reactive C3d on the surface of myelin sheaths in neuropathy. Journal of Neuroimmunology, 18, 231-244
16. Ichimura T, Hashimoto PH (1984) Fine structure of basement membranes of the capillary endothelium and perivascular astrocyte in some circumventricular organs by three-dimensional SEM. Journal of Ultrastructure Research, 86, 220-227
17. Janossy G, Bofill M, Poulter LW, Rawlings E, Burford GD, Navarrete C et al. (1986) Separate ontogeny of two macrophage-like accessory cell populations in the human fetus. Journal of Immunology, 136, 4354-4361
18. Kennedy A, Frank RN, Mancini MA, Lande M (1986) Collagens of the retinal microvascular basement membrane and of retinal microvascular cells in vitro. Experimental Eye Research, 42, 177- 199
19. Kermode AG, Tofts PS, MacManus DG, Kendall BE, Kingsley DPE, Moseley IF et al. (1988) Early lesions of multiple sclerosis. Lancet, 2, 1203- 1204
20. Mchedushviu G, CervssNavarro J, Hossmann K-A, Klatzo I (1986) Involvement of the blood-brain barrier in mechanisms of brain edema development. In: Brain Edema: A Pathogenetic Analysis. Edited by G. Mchedlishvili, J. Cervds-Navarro, K.-A. Hossmann and I. Klatzo. Budapest: Akaddmiai Kiad6, pp. 83-147
21. Miller DH, Rudge P, Johnson G, Kendall BE, MacManus DG, Moseley IF et al. (1988) Serial gadolinium enhanced magnetic resonance imaging in multiple sclerosis. Brain, 111, 927-939
22. Reindfleisch E (1863) Histologische Detail zu der grauene Degeneration von Gehim und Rueckenmark. Virchows Archiv fUr Pathologische Anatomie und Physiologic und fir Klinische Medizin, 26, 474-483
23. Roggendorf W, Cerv6s-Navarro J (1983) Ultrastructure of venules in human and cat brain. In: Cerebral Veins: An Experimental and Clinical Update. Edited by L. M. Auer and F. Loew. New York: Springer, pp. 39-46
24. Tsukada T, McNutt MA, Ross R, Gown AM (1987) HHF35, a muscle actin-specific monoclonal antibody: II. Reactivity in normal, reactive, and neoplastic human tissues. American Journal of Pathology, 127, 389-402
25. Vanguri P, Koski CL, Silverman B, Shin ML (1982) Complement activation by isolated myelin: activation of the classical pathway in the absence of myelin-specific antibodies. Proceedings of the National Academy of Sciences of the USA, 79, 3290-3294
26. Willoughby EW, Grochowskj E, Li DKB, Oger J, Kastrukoff LF, Paty DW (1989) Serial magnetic resonance scanning in multiple sclerosis: a second prospective study in relapsing patients. Annals of Neurology, 25, 43-49
27. Wisniewski HM, Bloom BR (1975) Primary demyelinalion as a nonspecific consequence of a cell-mediated immune reaction. Journal of Experimental Medicine, 141, 346- 359
28. Woodroofe MN, Bellamy AS, Feldmann M, Davison AN, Cuzner ML (1986) Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis: possible role for microglia in lesion growth. Journal of the Neurological Sciences, 74, 135-152