Human Immunodeficiency Virus-1 Protease. 2. Use of pH Rate Studies and Solvent Kinetic Isotope Effects To Elucidate Details of Chemical Mechanism

Biochemistry

Volumn 30, Issue 34, 1991, Pages 8454-8463

  Hyland, Lawrence J ^a   Tomaszek, Thaddeus A ^a   Meek, Thomas D ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; RECOMBINANT PROTEIN;

ARTICLE; ENZYME MECHANISM; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOTOPE EFFECT; NONHUMAN; PH; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; CATALYSIS; HIV PROTEASE; HYDROGEN-ION CONCENTRATION; KINETICS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; OXYGEN ISOTOPES; SOLVENTS; SUBSTRATE SPECIFICITY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0026005186     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00098a024     Document Type: Article

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