Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy

The Lancet

Volumn 338, Issue 8773, 1991, Pages 973-976

  Conway, M A ^a   Allis, J ^a   Ouwerkerk, R ^a   Niioka, T ^a   Rajagopalan, B ^a   Radda, G K ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATININE PHOSPHORIC ACID; PHOSPHORUS 31; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; HEART VENTRICLE HYPERTROPHY; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ADULT; AGED; AORTIC VALVE INSUFFICIENCY; AORTIC VALVE STENOSIS; CARDIOMYOPATHY, HYPERTROPHIC; COMPARATIVE STUDY; HUMAN; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGE; MYOCARDIUM; PHOSPHOCREATINE; PHOSPHORUS; SUPPORT, NON-U.S. GOV'T;

EID: 0026000171     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/0140-6736(91)91838-L     Document Type: Article

References (10)

1. Derangements in myocardial purine and pyrimidine nucleotide metabolism in patients with coronary artery disease and left ventricular hypertrophy
2. Characteristics of chronic left ventricular hypertrophy induced by subcoronary valvular aortic stenosis
3. The creatine kinase system in normal and diseased human myocardium
4. Energetic correlates of cardiac failure: changes in the creatine kinase system in the failing myocardium
5. 31P rotating frame NMR
6. 31P magnetic resonance spectroscopy of pressure overload hypertrophy in rats; effect of reduced perfusion pressure
7. Verapamil preserves myocardial performance and energy metabolism in left ventricular hypertrophy following ischemia and reperfusion
8. High energy phosphates and the force of contraction of cardiac muscle
9. Myocardial high energy phosphate stores in cardiac hypertrophy and heart failure
10. Regional myocardial metabolism of high-energy phosphates during isometric exercise in patients with coronary artery disease