The effect of inhibitors of nitric oxide biosynthesis and cyclic GMP formation on nerve‐evoked relaxation of human cavernosal smooth muscle

British Journal of Pharmacology

Volumn 104, Issue 3, 1991, Pages 755-759

  Pickard, R S ^a   Powell, P H ^a   Zar, M A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

methylene blue; nitric oxide; non adrenergic non cholinergic transmission; penile erection; Penis

Indexed keywords

ARGININE; ATROPINE; CYCLIC GMP; GLYCERYL TRINITRATE; GUANETHIDINE; METHYLENE BLUE; N(G) NITROARGININE; NITRIC OXIDE; NORADRENALIN; PROSTAGLANDIN E1; TETRODOTOXIN;

ARTICLE; AUTONOMIC NERVE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS CAVERNOSUM; ELECTRIC FIELD; ELECTROSTIMULATION; HUMAN; HUMAN TISSUE; MALE; NEUROTRANSMISSION; NONADRENERGIC NONCHOLINERGIC NERVE; PRIORITY JOURNAL; SMOOTH MUSCLE RELAXATION; STEREOSPECIFICITY;

ARGININE; AUTONOMIC NERVOUS SYSTEM; CYCLIC GMP; ELECTRIC STIMULATION; GUANETHIDINE; HUMAN; IN VITRO; MALE; METHYLENE BLUE; MUSCLE RELAXATION; MUSCLE, SMOOTH; NITRIC OXIDE; NITROARGININE; PENIS; SUPPORT, NON-U.S. GOV'T; SYNAPTIC TRANSMISSION;

EID: 0025999803     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1991.tb12500.x     Document Type: Article

References (28)

1. Is vasoactive intestinal polypeptide the principal transmitter involved in human penile erection
2. Extraction from ox retractor penis of an inhibitory substance which mimics its atropine‐resistant neurogenic relaxation
3. Relaxation of isolated human corpus spongiosum induced by vasoactive intestinal polypeptide, substance P, carbachol and electrical field stimulation
4. Cyclic GMP mediates neurogenic relaxation in the bovine retractor penis muscle
5. G‐nitroargnine inhibit non‐adrenergic, non‐cholinergic relaxation of the mouse anococcygeus muscle
6. G‐monomethyl arginine on the response of the bovine retractor penis to stimulation of its NANC nerves
7. G‐monomethyl‐l‐arginine on the response of the rat anococcygeus muscle to NANC nerve stimulation
8. Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerine, sodium nitrite and amyl nitrite
9. G‐nitro‐arginine and its methyl ester are potent inhibitors of non‐adrenergic, non‐cholinergic transmission in the rat anococcygeus
10. G‐nitro arginine inhibits non‐adrenergic, non‐cholinergic relaxation of human isolated corpus cavernosum
11. Endothelium‐induced relaxation by acetylcholine associated with larger rises in cyclic GMP in coronary arterial strips
12. Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle
13. G‐nitro‐l‐arginine: a potent inhibitor of endothelium derived relaxing factor formation
14. Activation of guanylate cyclase from rat liver and other tissues by sodium azide
15. Contraction and relaxation of the retractor penis muscle and the penile artery of the bull
16. Das anatomische und physiologische Verhalten der cavernosen Körper der Sexualorgane
17. Impotence
18. Macrophage oxidation of l‐arginine to nitrite and nitrate: nitric oxide is an intermediate
19. Selective blockade of endothelium‐dependent and glyceryl trinitrate‐induced relaxation by haemoglobin and by methylene blue in the rabbit aorta
20. Evidence that inhibitory factor extracted from bovine retractor penis is nitrite, whose acid‐activated derivative is stablized nitric oxide
21. G‐substituted analogues of l‐arginine on NANC relaxation of the anococcygeus, retractor penis and penile artery
22. G‐nitro arginine (l‐NOARG), a novel, l‐arginine‐reversible inhibitor of endothelium‐dependent vasodilatation in vitro
23. l‐arginine is the physiological precursor for the formation of nitric oxide in endothelium‐dependent relaxation
24. Evidence that nitric oxide mediates human penile erection
25. Local control of penile erection: nerves, smooth muscle, and endothlium
26. Cholinergic neurotransmission in human corpus cavernosum. I. Responses of isolated tissue
27. G‐monomethyl arginine on the inhibitory transmission of the human corpus cavernosum penis
28. G‐nitro arginine inhibits non‐adrenergic, non‐cholinergic relaxation of guinea‐pig isolated tracheal smooth muscle