Interleukin-1β induces an early decrease in insulin release, (pro)insulin biosynthesis and insulin mrna in mouse pancreatic islets by a mechanism dependent on gene transcription and protein synthesis

Autoimmunity

Volumn 10, Issue 2, 1991, Pages 107-113

  Eizirik, Décio L ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

(pro)insulin biosynthesis; Insulin mRNA; Insulin release; Interleukin 1; Pancreatic B cells; Pancreatic islets

Indexed keywords

CYCLOHEXIMIDE; DACTINOMYCIN; DNA; GLUCOSE; INSULIN; INTERLEUKIN 1BETA; MESSENGER RNA;

ARTICLE; BIOSYNTHESIS; DNA CONTENT; GENETIC TRANSCRIPTION; GLUCOSE METABOLISM; GLUCOSE OXIDATION; INSULIN RELEASE; INSULIN SYNTHESIS; PANCREAS ISLET; PROTEIN SYNTHESIS;

ANIMALS; DACTINOMYCIN; DNA REPLICATION; ENZYME INDUCTION; GLUCOSE; INSULIN; INTERLEUKIN-1; ISLETS OF LANGERHANS; MALE; MICE; ORGAN CULTURE TECHNIQUES; PROINSULIN; PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; RNA, MESSENGER; STIMULATION, CHEMICAL; TRANSCRIPTION, GENETIC;

EID: 0025995444     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939109004814     Document Type: Article

References (37)

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