Ocular absorption and distribution of loteprednol etabonate, a soft steroid, in rabbit eyes

Current Eye Research

Volumn 10, Issue 10, 1991, Pages 933-937

  Druzgala, Pascal ^a   Wu, Whei Mei ^b   Bodor, Nicholas ^b  

^a Xenon Vision Incorporation 1 ^*  (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; LOTEPREDNOL ETABONATE; STEROID;

AQUEOUS HUMOR; ARTICLE; CORNEA; DRUG ABSORPTION; DRUG DISTRIBUTION; EYE; METABOLISM; METABOLITE; RABBIT;

ABSORPTION; ADMINISTRATION, TOPICAL; ANDROSTADIENES; ANIMAL; ANTERIOR EYE SEGMENT; ANTI-INFLAMMATORY AGENTS, STEROIDAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CILIARY BODY; EYE; IRIS; RABBITS; TISSUE DISTRIBUTION;

EID: 0025991941     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.3109/02713689109020329     Document Type: Article

References (7)

1. Novel approaches to the design of safer drugs: soft drugs and site-specific chemical delivery systems
2. Soft drug principles and methods for the design of safer drugs
3. Soft drugs-10. Blanching activity and receptor binding activity of a new type of glucocorticoid: loteprednol etabonate
4. Influence of chain length on the in vitro hydrolysis of model ester prodrugs by ocular esterases
5. Formation of adrenaline in the iris-ciliary body from adrenalone diesters
6. Esterase activities in adult rabbit eyes
7. Esterase distribution in the rabbit cornea and its implication in ocular drug bioavailability