-
1
-
-
0023240345
-
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin
-
Chou, C. K., T. J. Dull, D. S. Russell, R. Gherzi, D. Lebwohl, A. Ullrich, and O. M. Rosen. 1987. Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. J. Biol. Chem. 262:1842-1847.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 1842-1847
-
-
Chou, C.K.1
Dull, T.J.2
Russell, D.S.3
Gherzi, R.4
Lebwohl, D.5
Ullrich, A.6
Rosen, O.M.7
-
2
-
-
0023665224
-
A mutant insulin receptor with defective tyrosine kinase displays not biologic activity and does not undergo endocylosis
-
McClain, D. A., H. Maegawa, J. Lee, T. J. Dull, A. Ullrich, and J. M. Olefsky. 1987. A mutant insulin receptor with defective tyrosine kinase displays not biologic activity and does not undergo endocylosis. J. Biol. Chem. 262:14663-14671.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 14663-14671
-
-
McClain, D.A.1
Maegawa, H.2
Lee, J.3
Dull, T.J.4
Ullrich, A.5
Olefsky, J.M.6
-
3
-
-
0038856677
-
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin and antibody-stimulated glucose uptake and receptor kinase activity
-
Ebina, Y., E. Araki, M. Taira, F. Shimada, M. Mori, C. S. Craik, K. Siddle, S. B. Pierce, R. A. Roth, and W. J. Rutter. 1987. Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin and antibody-stimulated glucose uptake and receptor kinase activity. Proc. Natl. Acad. Sci. USA. 84:704-708.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 704-708
-
-
Ebina, Y.1
Araki, E.2
Taira, M.3
Shimada, F.4
Mori, M.5
Craik, C.S.6
Siddle, K.7
Pierce, S.B.8
Roth, R.A.9
Rutter, W.J.10
-
4
-
-
0024272188
-
Detection of an alteration in the insulin receptor gene in a patient with insulin resistance, acanthosis nigricans, and the polycystic ovary syndrome (type A insulin resistance)
-
Moller, D. E., and J. S. Flier. 1988. Detection of an alteration in the insulin receptor gene in a patient with insulin resistance, acanthosis nigricans, and the polycystic ovary syndrome (type A insulin resistance). N. Engl. J. Med. 319:1526-1529.
-
(1988)
N. Engl. J. Med.
, vol.319
, pp. 1526-1529
-
-
Moller, D.E.1
Flier, J.S.2
-
5
-
-
0024323165
-
Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor
-
Odawara, M., T. Kadowaki, R. Yamamoto, Y. Shibasaki, K. Tobe, D. Accili, C. Bevins, Y. Mikami, N. Matsuura, Y. Akanuma, F. Takaku, S. I. Taylor, and M. Kasuga. 1989. Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor. Science (Wash. DC) 245:66-68.
-
(1989)
Science (Wash. DC)
, vol.245
, pp. 66-68
-
-
Odawara, M.1
Kadowaki, T.2
Yamamoto, R.3
Shibasaki, Y.4
Tobe, K.5
Accili, D.6
Bevins, C.7
Mikami, Y.8
Matsuura, N.9
Akanuma, Y.10
Takaku, F.11
Taylor, S.I.12
Kasuga, M.13
-
6
-
-
0024348797
-
Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor
-
Taira, M., N. Hashimoto, F. Shimada, Y. Suzuki, A. Kanatsuka, F. Nakamura, Y. Ebina, M. Tatibana, H. Makino, and S. Yoshida. 1989. Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor. Science (Wash. DC). 245:63-66.
-
(1989)
Science (Wash. DC)
, vol.245
, pp. 63-66
-
-
Taira, M.1
Hashimoto, N.2
Shimada, F.3
Suzuki, Y.4
Kanatsuka, A.5
Nakamura, F.6
Ebina, Y.7
Tatibana, M.8
Makino, H.9
Yoshida, S.10
-
7
-
-
0346310449
-
Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase
-
Morgan, D. O., L. Ho, L. J. Korn, and R. A. Roth. 1986. Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase. Proc. Natl. Acad. Sci. USA. 83:328-332.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 328-332
-
-
Morgan, D.O.1
Ho, L.2
Korn, L.J.3
Roth, R.A.4
-
8
-
-
0023941899
-
Alterations in insulin receptor autophosphorylation in insulin resistance: Correlation with altered sensitivity to glucose transport and antilipolysis to insulin
-
Takayama, S., C. R. Kahn, K. Kubo, and J. E. Foley. 1988. Alterations in insulin receptor autophosphorylation in insulin resistance: correlation with altered sensitivity to glucose transport and antilipolysis to insulin. J. Clin. Endocrinol. Metab. 66:992-999.
-
(1988)
J. Clin. Endocrinol. Metab.
, vol.66
, pp. 992-999
-
-
Takayama, S.1
Kahn, C.R.2
Kubo, K.3
Foley, J.E.4
-
9
-
-
0025115342
-
Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects
-
Thies, R. S., J. M. Molina, T. P. Ciaraldi, G. R. Freidenberg, and J. M. Olefsky. 1990. Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects. Diabetes. 39:250-259.
-
(1990)
Diabetes
, vol.39
, pp. 250-259
-
-
Thies, R.S.1
Molina, J.M.2
Ciaraldi, T.P.3
Freidenberg, G.R.4
Olefsky, J.M.5
-
10
-
-
0023798487
-
Reversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus: Effect of weight loss
-
Freidenberg, G. R., D. Reichart, J. M. Olefsky, and R. R. Henry. 1988. Reversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus: effect of weight loss. J. Clin. Invest. 82:1398-1406.
-
(1988)
J. Clin. Invest.
, vol.82
, pp. 1398-1406
-
-
Freidenberg, G.R.1
Reichart, D.2
Olefsky, J.M.3
Henry, R.R.4
-
11
-
-
84995849693
-
Relationship between skeletal muscle insulin receptor tyrosine kinase activity and in vivo insulin action in man
-
Abstr
-
Nyomba, B. L., V. M. Ossowski, and C. Bogardus. 1989. Relationship between skeletal muscle insulin receptor tyrosine kinase activity and in vivo insulin action in man. Diabetes. 38(Suppl. 2):58A. (Abstr.)
-
(1989)
Diabetes
, vol.38
, Issue.2 SUPPL.
-
-
Nyomba, B.L.1
Ossowski, V.M.2
Bogardus, C.3
-
12
-
-
0018602014
-
Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
-
National Diabetes Data Group. 1979. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes. 28:1039-1057.
-
(1979)
Diabetes
, vol.28
, pp. 1039-1057
-
-
-
13
-
-
0022504076
-
Effects of weight loss on mechanisms of hyperglycemia in obese non-insulin-dependent diabetes mellitus
-
Henry, R. R., P. Wallace, and J. M. Olefsky. 1986. Effects of weight loss on mechanisms of hyperglycemia in obese non-insulin-dependent diabetes mellitus. Diabetes. 35:990-998.
-
(1986)
Diabetes
, vol.35
, pp. 990-998
-
-
Henry, R.R.1
Wallace, P.2
Olefsky, J.M.3
-
14
-
-
0001213072
-
Muscle electrolytes in man determined by neutron activation analysis on needle biopsy specimen: A study on normal subjects, kidney patients, and patients with chronic diarrhea
-
Bergstrom, J. 1962. Muscle electrolytes in man determined by neutron activation analysis on needle biopsy specimen: a study on normal subjects, kidney patients, and patients with chronic diarrhea. Scand. J. Clin. Lab. Invest. 14(Suppl. 68):1-110.
-
(1962)
Scand. J. Clin. Lab. Invest.
, vol.14
, Issue.68 SUPPL.
, pp. 1-110
-
-
Bergstrom, J.1
-
15
-
-
0021134348
-
The effects of biosynthetic human proinsulin on carbohydrate metabolism
-
Revers, R. R., R. Henry, L. Schmeiser, O. Kolterman, R. Cohen, R. Bergenstal, K. Polonsky, J. Jaspan, A. Rubenstein, B. Frank, J. Galloway, and J. M. Olefsky. 1984. The effects of biosynthetic human proinsulin on carbohydrate metabolism. Diabetes. 33:762-770.
-
(1984)
Diabetes
, vol.33
, pp. 762-770
-
-
Revers, R.R.1
Henry, R.2
Schmeiser, L.3
Kolterman, O.4
Cohen, R.5
Bergenstal, R.6
Polonsky, K.7
Jaspan, J.8
Rubenstein, A.9
Frank, B.10
Galloway, J.11
Olefsky, J.M.12
-
16
-
-
0000648085
-
Influence of glucose loading and injected insulin on hepatic glucose output
-
Steele, R. 1959. Influence of glucose loading and injected insulin on hepatic glucose output. Ann. NY Acad. Sci. 82:420-430.
-
(1959)
Ann. NY Acad. Sci.
, vol.82
, pp. 420-430
-
-
Steele, R.1
-
17
-
-
0017337076
-
Gluconeogenesis: Methodological approaches in vivo
-
Chiasson, J. L., J. E. Liljenqvist, W. W. Lacy, A. S. Jennings, and A. Cherrington. 1977. Gluconeogenesis: methodological approaches in vivo. Fed. Proc. 36:229-235.
-
(1977)
Fed. Proc.
, vol.36
, pp. 229-235
-
-
Chiasson, J.L.1
Liljenqvist, J.E.2
Lacy, W.W.3
Jennings, A.S.4
Cherrington, A.5
-
18
-
-
0019907076
-
In vivo deactivation of peripheral, hepatic, and pancreatic insulin action in man
-
Gray, R. S., J. A. Scarlett, J. Griffin, J. M. Olefsky, and O. G. Kolterman. 1982. In vivo deactivation of peripheral, hepatic, and pancreatic insulin action in man. Diabetes. 31:929-936.
-
(1982)
Diabetes
, vol.31
, pp. 929-936
-
-
Gray, R.S.1
Scarlett, J.A.2
Griffin, J.3
Olefsky, J.M.4
Kolterman, O.G.5
-
19
-
-
0015146643
-
Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays
-
Desbuquois, B., and G. D. Aurbach. 1971. Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays. J. Clin. Endocrinol. Metab. 33:732-738.
-
(1971)
J. Clin. Endocrinol. Metab.
, vol.33
, pp. 732-738
-
-
Desbuquois, B.1
Aurbach, G.D.2
-
20
-
-
0022407111
-
Insulin receptor kinase activity in rat liver: Regulation by fasting and high carbohydrate feeding
-
Freidenberg, G. R., H. H. Klein, R. Cordera, and J. M. Olefsky. 1985. Insulin receptor kinase activity in rat liver: regulation by fasting and high carbohydrate feeding. J. Biol. Chem. 260:12444-12453.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 12444-12453
-
-
Freidenberg, G.R.1
Klein, H.H.2
Cordera, R.3
Olefsky, J.M.4
-
21
-
-
0014806678
-
Protein purification by affinity chromatography: Derivatization of agarose and polyacrylamide beads
-
Cuatrecasas, P. 1970. Protein purification by affinity chromatography: derivatization of agarose and polyacrylamide beads. J. Biol. Chem. 245:3059-3065.
-
(1970)
J. Biol. Chem.
, vol.245
, pp. 3059-3065
-
-
Cuatrecasas, P.1
-
22
-
-
0023654839
-
Post-transitional acquisition of insulin binding capacity by the insulin receptor proreceptor: Correlation to recognition by autoimmune antibody
-
Olson, T. S., and M. D. Lane. 1987. Post-transitional acquisition of insulin binding capacity by the insulin receptor proreceptor: correlation to recognition by autoimmune antibody. J. Biol. Chem. 262:6816-6822.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 6816-6822
-
-
Olson, T.S.1
Lane, M.D.2
-
23
-
-
0021136310
-
Primary culture of isolated adipocytes. A new model to study insulin receptor regulation and insulin action
-
Marshall, S., W. T. Garvey, and M. Geller. 1984. Primary culture of isolated adipocytes. A new model to study insulin receptor regulation and insulin action. J. Biol. Chem. 259:6376-6384.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 6376-6384
-
-
Marshall, S.1
Garvey, W.T.2
Geller, M.3
-
24
-
-
0023669291
-
Comparison of insulin and insulin-like growth factor I receptors from rat skeletal muscle and L6 myocytes
-
Burant, C. R., M. K. Treutelaar, K. D. Allen, D. A. Sens, and M. G. Buse. 1987. Comparison of insulin and insulin-like growth factor I receptors from rat skeletal muscle and L6 myocytes. Biochem. Biophys. Res. Commun. 147:100-107.
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.147
, pp. 100-107
-
-
Burant, C.R.1
Treutelaar, M.K.2
Allen, K.D.3
Sens, D.A.4
Buse, M.G.5
-
25
-
-
0023767025
-
Phenylarsine oxide and denervation effects on hormone-stimulated glucose transport
-
Sowell, M. O., K. A. Robinson, and M. G. Buse. 1988. Phenylarsine oxide and denervation effects on hormone-stimulated glucose transport. Am. J. Physiol. 255:E159-E165.
-
(1988)
Am. J. Physiol.
, vol.255
-
-
Sowell, M.O.1
Robinson, K.A.2
Buse, M.G.3
-
26
-
-
0018650188
-
Effects and binding of insulin-like growth factor I in the isolated soleus muscle of lean and obese mice: Comparison with insulin
-
Poggi, C., Y. LeMarchand-Brustel, J. Zapf, E. R. Froesch, and P. Freychet. 1979. Effects and binding of insulin-like growth factor I in the isolated soleus muscle of lean and obese mice: comparison with insulin. Endocrinology. 105:723-730.
-
(1979)
Endocrinology
, vol.105
, pp. 723-730
-
-
Poggi, C.1
Lemarchand-Brustel, Y.2
Zapf, J.3
Froesch, E.R.4
Freychet, P.5
-
27
-
-
0022978836
-
Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes: An in vitro system to measure histone kinase activity of insulin receptors activated in vitro
-
Freidenberg, G. R., M. Kladde, and J. M. Olefsky. 1986. Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes: an in vitro system to measure histone kinase activity of insulin receptors activated in vitro. J. Biol. Chem. 261:4691-4697.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 4691-4697
-
-
Freidenberg, G.R.1
Kladde, M.2
Olefsky, J.M.3
-
28
-
-
0021990787
-
The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus
-
Garvey, W. T., J. M. Olefsky, J. Griffin, R. F. Hamman, and O. G. Kolterman. 1985. The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus. Diabetes. 34:222-234.
-
(1985)
Diabetes
, vol.34
, pp. 222-234
-
-
Garvey, W.T.1
Olefsky, J.M.2
Griffin, J.3
Hamman, R.F.4
Kolterman, O.G.5
-
29
-
-
85003195436
-
Cortisol-induced insulin resistance in man: Impaired suppression of glucose production and stimulation of glucose utilization due to a postreceptor defect of insulin action
-
Rizza, R. A., L. J. Mandarino, and J. E. Gerich. 1982. Cortisol-induced insulin resistance in man: impaired suppression of glucose production and stimulation of glucose utilization due to a postreceptor defect of insulin action. J. Clin. Endocrinol. Metab. 54:131-138.
-
(1982)
J. Clin. Endocrinol. Metab.
, vol.54
, pp. 131-138
-
-
Rizza, R.A.1
Mandarino, L.J.2
Gerich, J.E.3
-
30
-
-
0019762341
-
The effect of insulin on the disposal of intravenous glucose: Results from indirect calorimetry and hepatic and femoral venous catheterization
-
DeFronzo, R. A., E. Jacot, E. Jequier, E. Maeder, J. Wahren, and J. P. Felber. 1981. The effect of insulin on the disposal of intravenous glucose: results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes. 30:1000-1007.
-
(1981)
Diabetes
, vol.30
, pp. 1000-1007
-
-
DeFronzo, R.A.1
Jacot, E.2
Jequier, E.3
Maeder, E.4
Wahren, J.5
Felber, J.P.6
-
31
-
-
0024535094
-
Insulin-receptor kinase activity correlates with in vivo insulin action
-
Bryer-Ash, M. 1989. Insulin-receptor kinase activity correlates with in vivo insulin action. Diabetes. 38:108-116.
-
(1989)
Diabetes
, vol.38
, pp. 108-116
-
-
Bryer-Ash, M.1
-
32
-
-
0015240302
-
The relationship between the insulin-binding capacity of fat cells and the cellular response to insulin
-
Kono, T., and F. W. Barham. 1971. The relationship between the insulin-binding capacity of fat cells and the cellular response to insulin. J. Biol. Chem. 246:6210-6216.
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 6210-6216
-
-
Kono, T.1
Barham, F.W.2
-
33
-
-
0017093234
-
Effects of fasting on insulin binding, glucose transport, and glucose oxidation in isolated rat adipocytes: Relationships between insulin receptors and insulin action
-
Olefsky, J. M. 1976. Effects of fasting on insulin binding, glucose transport, and glucose oxidation in isolated rat adipocytes: relationships between insulin receptors and insulin action. J. Clin. Invest. 58:1450-1460.
-
(1976)
J. Clin. Invest.
, vol.58
, pp. 1450-1460
-
-
Olefsky, J.M.1
-
34
-
-
0023120916
-
Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic (NIDDM) subjects
-
Freidenberg, G. R., R. R. Henry, H. H. Klein, D. R. Reichart, and J. M. Olefsky. 1987. Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic (NIDDM) subjects. J Clin. Invest. 79:240-250.
-
(1987)
J Clin. Invest.
, vol.79
, pp. 240-250
-
-
Freidenberg, G.R.1
Henry, R.R.2
Klein, H.H.3
Reichart, D.R.4
Olefsky, J.M.5
-
35
-
-
0022606922
-
Characterization of binding and phosphorylation defects of erythrocyte insulin receptor in the Type A syndrome of insulin resistance
-
Grigorescu, F., J. S. Flier, and C. R. Kahn. 1986. Characterization of binding and phosphorylation defects of erythrocyte insulin receptor in the Type A syndrome of insulin resistance. Diabetes. 35:127-138.
-
(1986)
Diabetes
, vol.35
, pp. 127-138
-
-
Grigorescu, F.1
Flier, J.S.2
Kahn, C.R.3
-
36
-
-
0021082877
-
Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I
-
Rubin, J. B., M. A. Shia, and P. F. Pilch. 1983. Stimulation of tyrosine-specific phosphorylation in vitro by insulin-like growth factor I. Nature (Lond.). 305:438-440.
-
(1983)
Nature (Lond.)
, vol.305
, pp. 438-440
-
-
Rubin, J.B.1
Shia, M.A.2
Pilch, P.F.3
-
37
-
-
0022978798
-
Similar control mechanisms regulate the insulin and type I insulin-like growth factor receptor kinases. Affinity-purified insulin-like growth factor I receptor kinase is activated by tyrosine phosphorylation of its beta subunit
-
Yu, K. T., M. A. Peters, and M. P. Czech. 1986. Similar control mechanisms regulate the insulin and type I insulin-like growth factor receptor kinases. Affinity-purified insulin-like growth factor I receptor kinase is activated by tyrosine phosphorylation of its beta subunit. J. Biol. Chem. 261:11341-11349.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 11341-11349
-
-
Yu, K.T.1
Peters, M.A.2
Czech, M.P.3
|