Catalysis by cytochrome P-450 of an oxidative reaction in xenobiotic aldehyde metabolism: Deformylation with olefin formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 88, Issue 20, 1991, Pages 8963-8966

  Roberts, Elizabeth S ^a   Vaz, Alfin D N ^a   Coon, Minor J ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Branched chain aldehydes; Citronellal; Isoforms of P 450; Peroxy intermediates; Steroid demethylation reactions

Indexed keywords

ORYCTOLAGUS CUNICULUS; ANIMALIA;

ALDEHYDE; ALKENE; CITRONELLAL; CYTOCHROME P450 ISOENZYME;

ANIMAL TISSUE; ARTICLE; LIVER MICROSOME; NONHUMAN; NOSE; PRIORITY JOURNAL; XENOBIOTIC METABOLISM;

ACETONE; ALDEHYDES; ANIMAL; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; MASS FRAGMENTOGRAPHY; MICROSOMES, LIVER; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; RABBITS; SUPPORT, U.S. GOV'T, P.H.S.; XENOBIOTICS;

EID: 0025990208     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.88.20.8963     Document Type: Article

References (27)

1. Vaz, A. D. N., Roberts, E. S. & Coon, M. J. (1991) J. Am. Chem. Soc. 113, 5886-5887.
2. Fishman, J. (1982) Cancer Res. 42, 3277s-3280s.
3. Alexander, K., Akhtar, M., Boar, R. B., McGhie, J. F. & Barton, D. H. R. (1972) J. Chem. Soc. Chem. Commun., 383-385.
4. Feron, V. J., Til, H. P., de Vrijer, F., Woutersen, R. A., Cassee, F. R. & van Bladeren, P. J. (1991) Mutat. Res. 259, 363-385.
5. Nebert, D. W., Nelson, D. R., Coon, M. J., Estabrook, R. W., Feyereisen, R., Fujii-Kuriyama, Y., Gonzalez, F. J., Guengerich, F. P., Gunsalus, I. C., Johnson, E. F., Loper, J. C., Sato, R., Waterman, M. R. & Waxman, D. J. (1991) DNA Cell Biol. 10, 1-14.
6. Ding, X. & Coon, M. J. (1988) Biochemistry 27, 8330-8337.
7. Ding, X. & Coon, M. J. (1991) Methods Enzymol., in press.
8. Morgan, E. T., Koop, D. R. & Coon, M. J. (1983) Biochem. Biophys. Res. Commun. 112, 8-13.
9. Coon, M. J., van der Hoeven, T. A., Dahl, S. B. & Haugen, D. A. (1978) Methods Enzymol. 52, 109-117.
10. Koop, D. R., Crump, B. L., Nordblom, G. D. & Coon, M. J. (1985) Proc. Natl. Acad. Sci. USA 82, 4065-4069.
11. French, J. S. & Coon, M. J. (1979) Arch. Biochem. Biophys. 195, 565-577.
12. McAuliffe, C. (1966) J. Phys. Chem. 70, 1267-1272.
13. Stephen, H. & Stephen, T., eds. (1963) Solubilities of Inorganic and Organic Compounds (Macmillan, New York), Vol. 1, Part 2, p. 1207.
14. Nordblom, G. D. & Coon, M. J. (1977) Arch. Biochem. Biophys. 180, 343-347.
15. Debey, P. & Balny, C. (1973) Biochimie Paris 55, 329-332.
16. Bartoli, G. M., Galeotti, T., Palombini, G., Parisi, G. & Azzi, A. (1977) Arch. Biochem. Biophys. 184, 276-281.
17. Auclair, C., de Prost, D. & Hakim, J. (1978) Biochem. Pharmacol. 27, 355-358.
18. Yang, C. S., Tu, Y. Y., Koop, D. R. & Coon, M. J. (1985) Cancer Res. 45, 1140-1145.
19. Ding, X. & Coon, M. J. (1990) Mol. Pharmacol. 37, 489-496.
20. Pevsner, J., Hou, V., Snowman, A. M. & Snyder, S. H. (1990) J. Biol. Chem. 265, 6118-6125.
21. Akhtar, M., Calder, M. R., Corina, D. L. & Wright, J. N. (1982) Biochem. J. 210, 569-580.
22. Stevenson, D. E., Wright, J. N. & Akhtar, M. (1988) J. Chem. Soc. Perkin Trans. I. 1, 2043-2052.
23. Cole, P. A., Bean, J. M. & Robinson, C. H. (1990) Proc. Natl. Acad. Sci. USA 87, 2999-3003.
24. Yoshida, Y., Aoyama, Y., Sonoda, Y. & Sato, Y. (1990) in Proceedings of the VIIIth International Symposium on Microsomes and Drug Oxidations, eds. Ingelman-Sundberg, M., Gustafsson, J.-Å. & Orrenius, S. (Karolinska Institute, Stockholm), p. 118.
25. Fischer, R. T., Trzaskos, J. M., Magolda, R. L., Ko, S. S., Brosz, C. S. & Larsen, B. (1991) J. Biol. Chem. 266, 6124-6132.
26. Watanabe, Y. & Ishimura, Y. (1989) J. Am. Chem. Soc. 111, 410-411.
27. White, R. E. & Coon, M. J. (1980) Annu. Rev. Biochem. 49, 315-356.