Prevention of High-Altitude Pulmonary Edema by Nifedipine

New England Journal of Medicine

Volumn 325, Issue 18, 1991, Pages 1284-1289

  Bartsch, Peter ^a   Maggiorini, Marco ^b   Ritter, Manfred ^b   Noti, Christof ^c   Vock, Peter ^c   Oelz, Oswald ^b  

^a Swiss School of Sports ^*  (Germany)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

NIFEDIPINE;

ADULT; ALTITUDE DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FEMALE; HUMAN; LUNG ARTERY PRESSURE; LUNG EDEMA; MALE; MOUNTAINEERING; ORAL DRUG ADMINISTRATION; PREVENTION; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION;

ADULT; ALTITUDE SICKNESS; BLOOD PRESSURE; DELAYED-ACTION PREPARATIONS; FEMALE; HUMAN; MALE; MIDDLE AGE; MOUNTAINEERING; NIFEDIPINE; PULMONARY ARTERY; PULMONARY EDEMA; SUPPORT, NON-U.S. GOV'T;

EID: 0025988702     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199110313251805     Document Type: Article

References (42)

1. Houston C.S. Acute pulmonary edema of high altitude. N Engl J Med 1960; 263:478-480
2. Singh I., Capila C.C., Khanna P.K., Nanda R.B., Rao B.D.P. High-altitude pulmonary edema. Lancet 1965; 1:229-234
3. Hackett P.H., Rennie D. The incidence, importance, and prophylaxis of acute mountain sickness. Lancet 1976; 2:1149-1154
4. Bartsch P., Vock P., Maggiorini M., et al. Respiratory symptoms, radiographic and physiologic correlations at high altitude. In: Sutton JR, Coates G, Remmers JE, eds. Hypoxia: the adaptations. Toronto: B.C. Decker, 1990: 241-5.
5. Hochstrasser J., Nanzer A., Oelz O. Das Hohenodem in den Schweizer Alpen. Schweiz Med Wochenschr 1986; 116:866-873
6. Lobenhoffer H.P., Zink R.A., Brendel W. High altitude pulmonary edema: analysis of 166 cases. In: Brendel W, Zink RA, eds. High altitude physiology and medicine. New York: Springer-Verlag, 1982: 219-31.
7. Hultgren H.N., Lopez C.E., Lundberg E., Miller H. Physiologic studies of pulmonary edema at high altitude. Circulation 1964; 29:393-408.
8. Penaloza D., Sime F. Circulatory dynamics during high altitude pulmonary edema. Am J Cardiol 1969; 23:369-378
9. Antezana G., Leguia G., Morales Guzman A., Coudert J., Spielvogel H. Hemodynamic study of high altitude pulmonary edema (12,200 ft). In: Brendel W, Zink RA, eds. High altitude physiology and medicine. New York: Springer-Verlag, 1982: 232-41.
10. Schoene R.B., Swenson E.R., Pizzo C.J., et al. The lung at high altitude: bronchoalveolar lavage in acute mountain sickness and pulmonary edema. J Appl Physiol 1988; 64:2605-2613
11. Hackett P.H., Bertman J., Rodriguez G., Tenney J. Pulmonary edema fluid protein in high-altitude pulmonary edema. JAMA 1986; 256:36.
12. Kobayashi T., Koyama S., Kubo K., Fukushima M., Kusama S. Clinical features of patients with high-altitude pulmonary edema in Japan. Chest 1987; 92:814-821
13. Hultgren H.N. High altitude pulmonary edema. In: Staub NC, ed. Lung water and solute exchange. Vol. 7 of Lung biology in health and disease. New York: Marcel Dekker, 1978: 437-69.
14. Schoene R.B. Pulmonary edema at high altitude: review, pathophysiology, and update. Clin Chest Med 1985; 6:491-507.
15. Hackett P.H., Roach R.C. High altitude pulmonary edema. J Wilderness Med 1990; 1:3-26.
16. Staub N.C. Pulmonary edema — hypoxia and overperfusion. N Engl J Med 1980; 302:1085-1087
17. Hultgren H.N., Graver R.F., Hartley L.H. Abnormal circulatory responses to high altitude in subjects with a previous history of high-altitude pulmonary edema. Circulation 1971; 44:759-770
18. Fasules J.W., Wiggins J.W., Wolfe R.R. Increased lung vasoreactivity in children from Leadville, Colorado, after recovery from high-altitude pulmonary edema. Circulation 1985; 72:957-962
19. Kawashima A., Kubo K., Kobayashi T., Sekiguchi M. Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema. J Appl Physiol 1989; 67:1982-1989
20. Yagi H., Yamada H., Kobayashi T., Sekiguchi M. Doppler assessment of pulmonary hypertension induced by hypoxic breathing in subjects susceptible to high altitude pulmonary edema. Am Rev Respir Dis 1990; 142:796-801.
21. Hackett P.H., Creagh C.E., Grover R.F., et al. High-altitude pulmonary edema in persons without the right pulmonary artery. N Engl J Med 1980; 302:1070-1073
22. Oelz O., Maggiorini M., Ritter M., et al. Nifedipine for high altitude pulmonary oedema. Lancet 1989; 2:1241-1244
23. Rämsch K.-D., Graefe K.H., Scherling D., Sommer J., Ziegler R. Pharmacokinetics and metabolism of calcium-blocking agents nifedipine, nitrendipine, and nimodipine. Am J Nephrol 1986; 6:Suppl 1:73-80.
24. Kuhlmann J., Graefe K.-H., Rämsch K.-D., Ziegler R. Clinical pharmacology. In: Krebs R, ed. Treatment of cardiovascular diseases by Adalat (nifedipine). Stuttgart, Germany: Schattauer, 1986: 120-34.
25. Yock P.G., Popp R.L. Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation. Circulation 1984; 70:657-662
26. Hatle L. Non-invasive methods of measuring pulmonary artery pressure and flow velocity. In: Chazov EI, Smirnov VN, Oganov RG, eds. Cardiology, an international perspective. Vol. 2. New York: Plenum Press, 1984: 783-90.
27. Vock P., Fretz C., Franciolli M., Bartsch P. High-altitude pulmonary edema: findings at high-altitude chest radiography and physical examination. Radiology 1989; 170:661-666
28. Birmingham Medical Research Expeditionary Society Mountain Sickness Study Group. Acetazolamide in control of acute mountain sickness. Lancet 1981; 1:180-183
29. Bartsch P., Waber U., Haeberli A., et al. Enhanced fibrin formation in high-altitude pulmonary edema. J Appl Physiol 1987; 63:752-757
30. Johnson T.S., Rock P.B. Acute mountain sickness. N Engl J Med 1988; 319:841-845
31. Kuhlmann J., Graefe K.-H., Ramsch K.-D., Ziegler R. Clinical pharmacology. In: Krebs R, ed. Treatment of cardiovascular diseases by Adalat (nifedipine). Stuttgart, Germany: Schattauer, 1986: 107-20.
32. Bärtsch P., Haeberli A., Franciolli M., Kruithof E.K., Straub P.W. Coagulation and fibrinolysis in acute mountain sickness and beginning pulmonary edema. J Appl Physiol 1989; 66:2f36-44.
33. Bärtsch P., Lämmle B., Huber I., et al. Contact phase of blood coagulation is not activated in edema of high altitude. J Appl Physiol 1989; 67: 1336-40.
34. Bärtsch P., Maggiorini M., Schobersberger W., et al. Enhanced exercise-induced rise of aldosterone and vasopressin preceding mountain sickness. J Appl Physiol 1991; 71:136-143
35. Kronenberg R.S., Safar P., Lee J., et al. Pulmonary artery pressure and alveolar gas exchange in man during acclimatization to 12,470 feet. J Clin Invest 1971; 50:827-837
36. Reeves J.T., Groves B.M., Sutton J.R., et al. Operation Everest II: preservation of cardiac function at extreme altitude. J Appl Physiol 1987; 63: 531-9.
37. Oelz O., Noti C., Ritter M., Jenni R., Bärtsch P. Nifedipine for high altitude pulmonary oedema. Lancet 1991; 337:556.
38. Simonneau E.P., Escourrou P., Duroux P., Lockhart A. Inhibition of hypoxic pulmonary vasoconstriction by nifedipine. N Engl J Med 1981; 304: 1582-5.
39. Malo P.E., Wasserman M.A. The effect of calcium antagonists on histamine and leukotriene-induced tracheal microvascular permeability in the guinea pig. Prostaglandins 1986; 32:221-233
40. Toyofuku T., Koyama S., Kobayashi T., Kusama S., Ueda G. Effects of polycations on pulmonary vascular permeability in conscious sheep. J Clin Invest 1989; 83:2063-2069
41. Lum H., Del Vecchio P.J., Schneider A.S., Goligorsky M.S., Malik A.B. Calcium dependence of the thrombin-induced increase in endothelial albumin permeability. J Appl Physiol 1989; 66:1471-1476
42. Hackett P.H., Greene E.R., Roach R.C., Feil P., Selland M. Nifedipine and hydralazine for treatment of high altitude pulmonary edema. In: Sutton JR, Coates G, Remmers JE, eds. Hypoxia: the adaptations. Toronto: B.C. Decker, 1990: 291. abstract.