Relationship between glial reaction to a stab wound and tumor development after receiving transplacental ethylnitrosourea in the rat

Acta Neuropathologica

Volumn 83, Issue 1, 1991, Pages 30-38

  Schiffer, D ^a   Giordana, M T ^a   Vigliani, M C ^a   Cavalla, P ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Brain injury; Bromodeoxyuridine; Ethylnitrosourea; Gliomas; rat

Indexed keywords

BROXURIDINE; ETHYLNITROSOUREA; GLIAL FIBRILLARY ACIDIC PROTEIN; VIMENTIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; BASAL GANGLION; BRAIN CORTEX; CARCINOGENESIS; CELL DAMAGE; CELL DIVISION; CELL KINETICS; CONTROLLED STUDY; GLIA CELL; GLIOMA; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PLACENTAL TRANSFER; PRIORITY JOURNAL; RAT; STAB WOUND; WHITE MATTER;

ANIMAL; BRAIN; BROMODEOXYURIDINE; ETHYLNITROSOUREA; FEMALE; INJECTIONS; MATERNAL-FETAL EXCHANGE; NEOPLASMS, EXPERIMENTAL; NEUROGLIA; PHENOTYPE; PREGNANCY; RATS; RATS, INBRED F344; WOUNDS, STAB;

EID: 0025986435     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/BF00294427     Document Type: Article

References (43)

1. Fine structure of reactive cells in injured nervous tissue labeled with [3H]thymidine injected before injury
2. Gliomatous transformation and demyelinating diseases
3. Deposition of scar tissue in the central nervous system
4. Short- and long-term effects of methyl- and ethylnitrosurea (MNU and ENU) on the developing nervous system of the rat. II. Short term: Concluding remarks on chemical neuroncogenesis
5. The proliferation of astrocytes around a needle wound in the rat brain
6. The Vimentin-GFA protein transition in rat neuroglia cytoskeleton occurs at the time of myelination
7. Selective induction of malignant tumours of the nervous system by resorptive carcinogens
8. Astrocyte cell lineage. V. Similarity of astrocytes that form in the presence of dBcAMP in cultures to reactive astrocytes in vivo
9. Transplacental ENU tumors of the rat: immunohistochemical contribution to the recognition of cell types
10. Radial glia rats treated transplacentally by ENU
11. Cerebral cicatrix. The reaction of neuroglia and microglia to brain wounds
12. Gliogenesis of astrocytes and oligodendrocytes in the neocortical gray and white matter of the adult rat: electron microscopic analysis of light radioautographs
13. Chemical neurooncogenesis: role of structural DNA modification, DNA repair and neuronal target cell population
14. Transplacental production of neoplasm of the nervous system in Sprague-Dawley rats
15. The transformation process
16. Chemical induction of tumours in the nervous system
17. The origin of experimental brain tumours: a sequential study
18. The development of experimental brain tumors. A sequential light and electron microscope study of the subependymal plate. I. Early lesions
19. Fibrillary astrocytes proliferate to brain injury. A study combining immunoperoxidase technique for glial fibrillary acidic protein and autoradiography of tritiated thymidine
20. Vimentin intermediate filaments in cultures of human meningiomas
21. Reaction of oligodendrocytes and astrocytes to trauma and implantation. A combined autoradiographic and immunohistochemical study
22. Glial Fibrillary Acidic protein (GFAP) in rat brain tumors transplacentally induced by ethylnitrosourea (ENU)
23. Observation on the astrocyte response to a cerebral stab wound in adult rats
24. Morphology of transplacentally induced nervous system tumors in rats: some aspects of this model in neurooncology
25. Formale Pathogenese experimenteller Hirntumoren
26. Traumatische Regeneration und Resorptivkarzinogenese am Zentralnervensystem. I Mitteilung
27. Response of fetal and neonatal brain to injury
28. Trauma and demyelination as etiologic factors in the development of brain tumors
29. Trauma and brain tumors: an experimental study
30. Uptake of [3H]thymidine by corpus callosum cells in rats following a stab wound of the brain
31. Dividing and newly produced cells in the corpus callosum of adult mouse cerebrum as detected by light microscopic radioautography
32. Transition between immature radial glia and mature astrocytes studied with a monoclonal antibody to vimentin
33. Immunohistochemical characterization of rat central and peripheral nerve tumors induced by ethylnitrosourea
34. Expression of vimentin and glial fibrillary acidic protein in ethylnitrosourea-induced rat gliomas and glioma cell lines
35. Cerebral tumors induced by transplacental ENU: study of the different tumoral stages, particularly of early proliferations
36. Experimental brain tumors by transplacental ENU. Multifactorial study of latency period
37. Glial fibrillary acidic protein (GFAP) and vimentin in the experimental glial reaction of the rat brain
38. A shared antigenic determinant between natural killer cells and nervous tissue
39. Cell kinetic studies of different cell types in the developing and adult brain of the rat and the mouse. A review
40. Immunohistochemical properties of glial cells of ethylnitrosourea induced brain tumor in the rat
41. Evidence for division and transformation of neuroglia cells in the mouse brain, as derived from radioautography after injection of [3H]thymidine
42. Immunohistochemical studies on the proliferation of reactive astrocytes and expression of cytoskeletal proteins following brain injury in rats
43. Immunohistochemical studies on cellular character of microtumors induced by ethylnitrosourea in the rat brain utilizing anti-Leu-7 and anti-glial fibrillary acidic protein antibodies