메뉴 건너뛰기




Volumn 32, Issue 14, 1991, Pages 1725-1728

Radical cyclizations of N-vinylic α-chloroacetamides. 5-endo-trig and 4-exo-trig cyclizations

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE DERIVATIVE; PYRROLE DERIVATIVE;

EID: 0025978097     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)74314-0     Document Type: Article
Times cited : (99)

References (39)
  • 2
    • 0003119366 scopus 로고
    • A radical deoxygenation of primary alcohols by use of tri-n-butyltin hydride-sodium iodide, and its application to a radical cyclization.
    • (1983) Chemistry Letters , pp. 795
    • Ueno1    Tanaka2    Okawara3
  • 25
    • 84918602858 scopus 로고    scopus 로고
    • 3SnH were used.
  • 26
    • 84918644864 scopus 로고    scopus 로고
    • Stereochemistry of the cyclization products 5b,c and 9b,c was determined on the basis pf the thermodynamically controlled equilibrium experiments using t-BuOK/t-BuOH or EtONa/EtOH. Further support for the assignments came from NOE difference spectroscopy: for example, in 9c positive NOE effects were observed between 1-H and 4β-H, 3a-H and 9b-H, and 3a-H and 4α-H, while no effect was observed between 1-H and 9b-H. Details will be reported in due course.
  • 39
    • 84918604974 scopus 로고    scopus 로고
    • 4 followed by heating of the resulting sulfoxide in boiling toluene afforded α,β-unsaturated γ-lactam as a result of a syn-elimination of sulfenic acid. However, the corresponding sulfoxide derived from 21b was recovered unchanged.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.