Glucuronidation of mono(2-ethylhexyl)phthalate. Some enzyme characteristics and inhibition by bilirubin

Biochemical Pharmacology

Volumn 41, Issue 10, 1991, Pages 1493-1496

  Sjöberg, Per ^a   Egestad, Börje ^b   Klasson Wehler, Eva ^c   Gustafsson, Jan ^d  

^a MEDICAL PRODUCTS AGENCY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; GLUCURONOSYLTRANSFERASE; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; RADIOISOTOPE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCURONIDATION; GUINEA PIG; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; XENOBIOTIC METABOLISM;

ANIMAL; BILIRUBIN; BINDING, COMPETITIVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIETHYLHEXYL PHTHALATE; GLUCURONATES; GLUCURONOSYLTRANSFERASE; GUINEA PIGS; KINETICS; MALE; MICROSOMES, LIVER; SUPPORT, NON-U.S. GOV'T;

EID: 0025977839     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(91)90566-N     Document Type: Article

References (12)

1. Diethylhexyl phthalate as a factor in blood transfusion and haemodialysis
2. Dispositions of di- and mono-(2-ethylhexyl)phthalate in newborn infants subjected to exchange transfusions
3. Circulating concentrations of di-(2-ethylhexyl_phthalate and its de-esterified phthalic acid products following plasticizer exposure in patients receiving haemodialysis
4. Effects of di-(2-ethylhexyl)phthalate and five of its metabolites on rat testis in vivo and in vitro
5. The accumulation of mono-2-ethylhexyl phthalate (MEHP) during storage of whole blood and plasma
6. Pharmacokinetics, interactions with macromolecules and species differences in metabolism of DEHP
7. Metabolism and tissue distribution of mono-(2-ethylhexyl)-phthalate in the rat
8. Analysis by fast atom bombardment mass spectrometry of conjugated metabolites of bis(2-ethylhexyl)-phthalate
9. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
10. Induction and inhibition of conjugating enzymes with emphasis on UDP-glucuronyltranferases
11. Distribution of di- and mono-(2-ethylhexyl)phthalate in human plasma
12. Binding of bilirubin and other ligands to human serum albumin