Synthesis and Anti-HIV-1 Activity of 4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) Derivatives

Journal of Medicinal Chemistry

Volumn 34, Issue 2, 1991, Pages 746-751

  Kukla, Michael J ^a   Breslin, Henry J ^a   Fedde, Cynthia L ^a   Miranda, Milton ^a   Scott, Malcolm K ^a   Sherrill, Ronald G ^a   Pauwels, Rudi ^b   Raeymaekers, Alfons ^c   Van Gelder, Jozef ^c   Andries, Koen ^c   Janssen, Marcel A C ^c   De Clerq, Erik ^c   Janssen, Paul A J ^c  

^a JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

4,5,6,7 TETRAHYDRO 5 METHYL 6 (3 METHYL 2 BUTENYL)IMIDAZO[4,5,1 JK][1,4]BENZODIAZEPIN 2(1H) ONE; BENZODIAZEPINE DERIVATIVE; DIDANOSINE; IMIDAZO[4,5,1 JK] 1,4 BENZODIAZEPINE DERIVATIVE; TIBO DERIVATIVE; UNCLASSIFIED DRUG; ZALCITABINE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTIVIRAL AGENTS; BENZODIAZEPINONES; CHEMISTRY; HIV; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 0025973691     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00106a040     Document Type: Article

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