Activated CD3−CD16+ Natural Killer Cells Express a Subset of the Lymphokine Genes Induced in Activated αβ+ and γω+ T cells

Scandinavian Journal of Immunology

Volumn 33, Issue 3, 1991, Pages 247-252

  BIASSONI, R ^a,b   FERRINI, S ^b   PRIGIONE, I ^b   PELAK, V S ^a   SEKALY, R P ^b   LONG, E O ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CD3 ANTIGEN; COLONY STIMULATING FACTOR; CYTOKINE; LYMPHOKINE; T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; NATURAL KILLER CELL; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANTIGENS, CD3; ANTIGENS, DIFFERENTIATION; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BASE SEQUENCE; BLOTTING, NORTHERN; GENE EXPRESSION; HUMAN; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; LYMPHOKINES; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, FC; RECEPTORS, IGG; RNA; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTE SUBSETS;

EID: 0025972143     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.1991.tb01769.x     Document Type: Article

References (33)

1. CD3‐negative natural killer ceils express ζ TCR as part of a novel molecular complex
2. Interaction of Fc receptor (CD16) ligands induces transcription of inter‐leukin‐2 receptor (CD25) and lymphokine genes and expression of their products in human natural killer cells
3. Cloning of cDNA for human T‐cell replacing factor (interleukin‐5) and comparison with the murine homologue
4. Involvement of tumor necrosis factor in monocyte‐mediated rapid killing of Actinomycin D‐pretreated WEHI‐164 sarcoma ceils
5. CD3‐negative lymphokine‐activated cytotoxic cells express the CD3 epsilon gene
6. − major histocompatibility complex‐unrestricted cytotoxic cells
7. Identification of a putative second T‐cell receptor
8. ++ mobilization phosphoinositide turnover in human natural killer cells
9. Tumor targets stimulate IL‐2 activated killer cells to produce interferon‐γ and tumor necrosis factor
10. − lymphocytes to express their functional program(s)
11. Trans‐activation of human immunodeficiency virus occurs via a bimodal mechanism
12. Production of hematopoietic colony‐stimulating factors by human natural killer cells
13. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity
14. − clones expressing the putative T cell receptor gamma gene product
15. Analysis al the population and clonal levels
16. Surface markers of human lymphokine‐activated killer cells and their precursors. Analysis at the population and clonal level
17. − T lymphocytes
18. T‐cell growth factor: parameter of production and a quantitative microassay for activity
19. Cloning and expression of cDNA for human lymphotoxin. a lymphokine with tumor necrosis activity
20. Expression of human interferon cDNA in E. Coli and monkey cells
21. Complementary DNA for a novel human interleukin (BSF‐2) that induces B lymphocytes to produce immunoglobulin
22. A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein; ramification for the complex physiology of TNF
23. Cloning, sequence and expression of two distinct human interleukin‐1 complementary DNAs
24. Phenotypic and functional heterogeneity of human T cell clones producing alpha‐interferon
25. + LAK clones which produce intcricukin‐2
26. Functional analysis of two human T‐cell subpopulations; help and suppression of B‐cell responses by T‐cells bearing receptors for IgM or IgG
27. Isolation and characterization of an expressible cDNA encoding human IL‐3
28. Human cytolytic tell clones lacking surface expression of T cell receptor α/β or γ/ω Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction
29. Pleiotropy and redundancy: T cell‐derived lymphokines in the immune response
30. Human tumor necrosis: precursor structure, expression and homology to lymphotoxin
31. DO beta: a new beta chain gene in HLA‐D with a distinct regulation of expression
32. Human GMCSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins
33. Isolation and characterization of human interleukin cDNA clone, homologous to mouse B‐cell stimulatory factor‐1. that expresses B‐cell‐ and T‐cells stimulating activities