An improved method for the detection of DNA fragmentation

Journal of Immunological Methods

Volumn 136, Issue 1, 1991, Pages 125-131

  Facchinetti, A ^a   Tessarollo, L ^a   Mazzocchi, M ^a   Kingston, R ^a   Collavo, D ^a   Biasi, G ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Apoptosis detection; DNA fragmentation; Southern blot analysis

Indexed keywords

DNA FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SOUTHERN BLOTTING;

ANIMAL; CELL SURVIVAL; DNA; ETHIDIUM; MICE; MICE, INBRED C57BL; NUCLEIC ACID HYBRIDIZATION; STAINING AND LABELING; SUPPORT, NON-U.S. GOV'T;

ANIMALIA;

EID: 0025967255     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-1759(91)90258-H     Document Type: Article

References (20)

1. In vitro induction of immunological tolerance
2. Immunologic unresponsiveness to murine leukemia virus antigens: mechanism and role in tumor development
3. Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
4. Rapid in vivo effects of glucocorticoids on the integrity of rat lymphocyte genomic deoxyribonucleic acid
5. IL-2 addiction: withdrawal of growth factors activates a suicide program in dependent T cells
6. The role of nuclear damage in lysis of target cells by cytotoxic T lymphocytes
7. Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis
8. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
9. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
10. Apoptosis
11. Cellular signalling in programmed cell death (apoptosis)
12. Programmed death of autoreactive thymocytes
13. Mechanism of immune lysis. I Physiological distinction between target cell death mediated by cytotoxic T lymphocytes and antibody plus complement
14. DNA fragmentation: Manifestation of target cell destruction mediated by cytotoxic T-cell lines, lymphotoxin-secreting helper T-cell clones, and cell-free lymphotoxin-containing supernatant
15. Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes
16. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures
17. Detection of specific sequences among fragments separated by gel electrophoresis
18. Activation driven T cell death. I. Requirements for de novo transcription and translation and association with genome fragmentation
19. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
20. Cell death: the significance of apoptosis