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Volumn 41, Issue 3, 1991, Pages 349-359

P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CREMOPHOR; CYCLOSPORIN A; DAUNORUBICIN; GLYCOPROTEIN; N (3,4 DIMETHOXYPHENETHYL) N METHYL 2 (2 NAPHTHYL) 1,3 DITHIANE 2 PROPYLAMINE; VERAPAMIL;

EID: 0025966666     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(91)90531-9     Document Type: Article
Times cited : (78)

References (59)
  • 1
    • 0018097819 scopus 로고
    • Experimental therapeutics and kinetics: selection and overgrowth of specifically and permanently drug-resistant tumor cells
    • (1978) Semin Hematol , vol.15 , pp. 207
    • Skipper1    Schabel2    Lloyd3
  • 2
    • 0018569942 scopus 로고
    • A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate
    • (1979) Cancer Treat Rep , vol.63 , pp. 1727-1733
    • Goldie1    Coldman2
  • 3
    • 0014767029 scopus 로고
    • Cellular resistance to actinomycin D in chinese hamster cells in vitro: cross-resistance, radioautographic and cytogenetic studies
    • (1970) Cancer Res , vol.30 , pp. 1174-1184
    • Biedler1    Riehm2
  • 6
    • 0023006005 scopus 로고
    • Isolation and expression of a complementary DNA that confers multidrug resistance
    • (1986) Nature , vol.323 , pp. 728-731
    • Gros1    Neriah2    Croop3    Housman4
  • 10
    • 0021091295 scopus 로고
    • Reversal of acquired resistance to vinca alkaloids and anthracycline antibiotics
    • (1983) Cancer Treat Rep , vol.67 , pp. 889-894
    • Tsuruo1
  • 11
    • 0021679073 scopus 로고
    • Calcium channel blocker enhancement of anticancer drug cytotoxicity—a review
    • (1984) Cancer Drug Deliv , vol.1 , pp. 353-361
    • Helson1
  • 12
    • 0023937398 scopus 로고
    • Possible link between the intrinsic drug resistance of colon tumors and a detoxification mechanism of intestinal cells
    • (1988) Cancer Res , vol.48 , pp. 3025-3030
    • Klohs1    Steinkampf2
  • 17
    • 0024365556 scopus 로고
    • Identification of anthracyclines and related agents that retain preferential activity over Adriamycin in multidrug-resistant cell lines, and further resistance modification by verapamil and cyclosporin A
    • (1989) Cancer Chemother Pharmacol , vol.24 , pp. 284-290
    • Coley1    Twentyman2    Workman3
  • 19
    • 0021801398 scopus 로고
    • Promotion of daunorubucin uptake and toxicity by the calcium antagonist tiapamil and its analogs
    • (1985) Cancer Treat Rep , vol.69 , pp. 673-676
    • Kessel1    Wilberding2
  • 23
    • 0018609152 scopus 로고
    • Cell lines from human colon carcinoma with unusual cell products, double minutes and homogeneously staining regions
    • (1979) Cancer Res , vol.39 , pp. 4914-4929
    • Quinn1    Moore2    Morgan3    Woods4
  • 25
    • 0020523431 scopus 로고
    • Identification of two distinct regulatory regions adjacent to the human b-interferon gene
    • (1983) Cell , vol.34 , pp. 865-879
    • Zinn1    Dimaio2    Maniatis3
  • 30
    • 0345139075 scopus 로고
    • Functional role for the 170- to 180- kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 7785-7789
    • Hamada1    Tsuruo2
  • 34
    • 0019430432 scopus 로고
    • Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
    • (1981) Cancer Res , vol.41 , pp. 1967-1972
    • Tsuruo1    Iida2    Tsukagoshi3    Sakurai4
  • 35
    • 0018092541 scopus 로고
    • Carrier-mediated transport of daunorubicin, adriamycin and rubidazone in Ehrlich ascites tumour cells
    • (1978) Biochem Pharmacol , vol.27 , pp. 1221-1227
    • Skovsgaard1
  • 37
    • 0024421664 scopus 로고
    • Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells
    • (1989) Cancer Res , vol.49 , pp. 5002-5006
    • Yusa1    Tsuruo2
  • 39
    • 0024320713 scopus 로고
    • Equilibrium, kinetic and photoaffinity labeling studies of daunomycin binding to P-glycoprotein-containing membranes of multidrug-resistant Chinese hamster ovary cells
    • (1989) Eur J Biochem , vol.183 , pp. 189-197
    • Busche1    Tümmler2    Cano-Gauci3    Riordan4
  • 40
    • 0000622931 scopus 로고
    • Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7187-7191
    • Safa1
  • 41
    • 84914606923 scopus 로고    scopus 로고
    • Lankelma J, Spoelstra EC, Dekker H and Broxterman HJ, Evidence for daunomycin efflux from multidrug-resistant 2780AD human ovarian carcinoma cells against a concentration gradient. Biochim Biophys Acta, in press.
  • 43
    • 0024426842 scopus 로고
    • Saturable process involved in active efflux of vincristine as a mechanism of multidrug resistance in P388 leukemia cells
    • (1989) Pharmaceut Res , vol.6 , pp. 690-696
    • Watanabe1    Inaba2    Sugiyama3
  • 45
    • 0017345240 scopus 로고
    • Transport and binding of daunorubicin, adriamycin, and rubidazone in Ehrlich ascites tumour cells
    • (1977) Biochem Pharmacol , vol.26 , pp. 215-222
    • Skovsgaard1
  • 52
    • 0019518042 scopus 로고
    • A Fickian diffusion transport process with features of transport catalysis
    • (1981) J Gen Physiol , vol.78 , pp. 349
    • Dalmark1    Storm2
  • 54
    • 0342867391 scopus 로고
    • Drug transport in multidrug-resistant tumor cells—a revision of the pump-hypothesis
    • (1989) Anticancer Drugs , vol.191 , pp. 233-244
    • Skovsgaard1
  • 55
    • 0022993652 scopus 로고
    • Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins
    • (1986) Cell , vol.47 , pp. 371-380
    • Gros1    Croop2    Housman3
  • 56
    • 0022972654 scopus 로고
    • Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
    • (1986) Cell , vol.47 , pp. 381-389
    • Chen1    Chin2    Ueda3    Clark4    Pastan5    Gottesman6    Roninson7
  • 59
    • 0024307162 scopus 로고
    • Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance
    • (1989) Mol Cell Biol , vol.9 , pp. 5289-5297
    • Azzaria1    Schurr2    Gros3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.