AIDS virus infection and autoimmunity: A perspective of the clinical, immunological, and molecular origins of the autoallergic pathologies associated with HIV disease

Clinical Immunology and Immunopathology

Volumn 58, Issue 2, 1991, Pages 163-180

  Morrow, W John W ^a   Isenberg, David A ^b   Sobol, Robert E ^a   Stricker, Raphael B ^c   Kieber Emmons, Thomas ^a  

^a BIOGEN   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AUTOIMMUNITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; VIRUS INFECTION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; AMINO ACID SEQUENCE; AUTOIMMUNITY; HUMAN; MOLECULAR SEQUENCE DATA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025964293     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1016/0090-1229(91)90134-V     Document Type: Short Survey

References (122)

1. C-type RNA viruses and autoimmune disease
2. Chronic arthritis in goats caused by a retrovirus
3. Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome
4. Circulating immune complexes in AIDS
5. Precipitable immune complexes in healthy homosexual men, acquired immune deficiency syndrome and the related lymphadenopathy syndrome
6. Immune complexes in the acquired immunodeficiency syndrome (AIDS): Relationship to disease manifestation, risk group, and immunologic defect
7. Circulating immune complexes in patients with acquired immune deficiency syndrome contain the AIDS-associated retrovirus
8. The cooccurrence of Reiter's syndrome and acquired immunodeficiency
9. Inflammatory joint disease and human immunodeficiency virus infection
10. Association of human immunodeficiency virus infection and autoimmune phenomena
11. Seborrheic dermatitis in patients with acquired immunodeficiency syndrome
12. Renal disease in patients with AIDS: A clinicopathologic study
13. Glomerular lesions in the acquired immunodeficiency syndrome
14. Neurological complications of acquired immune deficiency syndrome: Analysis of 50 patients
15. Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): Experience at UCSF and review of the literature
16. Acute neuropathy coincident with seroconversion for anti-LAV/HTLV-III
17. Detection of natural autoantibodies in the serum of anti-HIV-positive individuals
18. Anti-cardiolipin antibodies (ACA) in human immunodeficiency virus (HIV) infected gay males may be associated with a deteriorating clinical course
19. Antibodies in human immunodeficiency syndrome (HIV) infection with musculoskeletal involvement
20. Polymyositis associated with AIDS retrovirus
21. Polymyositis in an immunodeficiency disease in monkeys induced by a type D retrovirus
22. Oral manifestations of primary and acquired immunodeficiency diseases in children
23. Parotid gland enlargement and xerostomia associated with labial sialadenitis in HIV-infected patients
24. A diffuse infiltrative CD8 lymphocytosis syndrome in human immunodeficiency virus (HIV) infection: A host immune response associated with HLA-DR5
25. Hematologic aspects of human immunodeficiency virus infection: Laboratory and clinical considerations
26. Thrombotic thrombocytopenic purpura in a human immunodeficiency virus (HIV)-seropositive homosexual man
27. Autoimmune thrombocytopenic purpura in homosexual men
28. Target platelet antigen in homosexual men with immune thrombocytopenia
29. Lupus anticoagulant in the acquired immunodeficiency syndrome
30. Circulating coagulation inhibitors in the acquired immunodeficiency syndrome
31. The Coombs' test and the acquired immunodeficiency syndrome
32. Positive direct antiglobulin test associated with hyperglobulinemia in acquired immunodeficiency syndrome (AIDS)
33. Do human T-lymphotropic viruses (HTLVs) and other enveloped viruses induce autoimmunity in multiple sclerosis?
34. Inflammatory neuropathy in homosexual men with lymphadenopathy
35. The use of plasmapheresis, lymphocytapheresis and staph protein-A immunoadsorption as an immunomodulatory therapy in patients with AIDS and AIDS-related conditions
36. Antibody-mediated peripheral neuropathies associated with ARC and AIDS: Successful treatment with plasmapheresis
37. On the mechanism of thrombocytopenia purpura in sexually active homosexual men
38. AIDS gastropathy: Antibodies to gastric parietal cell
39. Sperm and seminal plasma antibodies in acquired immune deficiency (AIDS) and other associated syndromes
40. Individuals infected with HIV possess antibodies against IL-2
41. Anti-corticosteroid antibodies in AIDS patients
42. Idiopathic production of interleukin-1 in acquired immune deficiency syndrome
43. Release of interleukin 1 inhibitory activity (contra-IL-1) by human monocyte-devived macrophages infected with human immunodeficiency virus in vitro and in vivo
44. 2 production by HIV
45. Interferon production in male homosexuals with the acquired immune-deficiency syndrome (AIDS) or generalized lymphadenopathy
46. AIDS as immune system activation: A model for pathogenesis
47. Immunopathogenic mechanisms of HIV infection
48. Human immunodeficiency virus-induced cytotoxicity for CD8 cells from some normal donors and virus-specific induction of a suppressor factor
49. Serum suppressive activity of HIV seropositive patients
50. Cytotoxic factor ssecreted by cells infected by human immunodeficiency virus type I
51. Elevated phagocytosis, oxidative burst, and F-actin formation in PMNs from individuals with intraoral manifestations of HIV infection
52. The N-dimensional network
53. When HIV meets the immune system: Network theory, alloimmunity, autoimmunity, and AIDS
54. Loss of Fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes
55. + cell d depletion
56. Anti-lymphocyte antibodies in the pathogenesis of SLE
57. Anti-lymphocyte antibodies in lethal mouse malaria. II. Induction of an autoantibody specific suppressor T cell by non-lethal P. yoelii
58. T lymphocyte subsets and antilymphocyte antibodies in lupus nephritis
59. Anti-lymphocytic antibodies in autoimmune chronic active hepatitis starting in childhood
60. Antilymphocyte serum factors in patients with acquired immunodeficiency syndrome
61. Antilymphocyte antibodies and seropositivity for retroviruses in groups at high risk for AIDS
62. Flow cytometric analysis of lymphocyte phenotypes in AIDS using monoclonal antibodies and simultaneous dual immunofluorescence
63. Lymphocytotoxic antibodies in the acquired immune deficiency syndrome (AIDS)
64. Cellular targets of antilymphocyte antibodies in AIDS and LAS
65. Anti-lymphocyte antibodies in patients with the acquired immune deficiency syndrome
66. The significance of antilymphocyte antibodies in patients with acquired immune deficiency syndrome (AIDS) and their sexual partners
67. + cells
68. + T cells in humans and monkeys
69. Anti-histone H2B antibodies in HIV seropositive individuals
70. Specificity of anti-lymphocyte antibodies in sera from patients with AIDS-related complex (ARC) and healthy homosexuals
71. Stress proteins and the immune response to mycobacteria—Antigens as virulence factors?
72. A role for heat shock proteins in inflammation?
73. HIV env glycoprotein shares a cross-reacting epitope with a surface protein present on activated human monocytes and involved in antigen presentation
74. Detection of anti-CD4 autoantibodies in the sera of HIV-infected patients using recombinant soluble CD4 molecules
75. Antibodies to soluble CD4 in HIV-1-infected individuals
76. Anti-class II antibodies in AIDS patients and AIDS MSG groups
77. Viruses, autoimmunity, and murine lymphoma
78. T cells can present antigens such as HIV gp120 targeted to their own surface molecules
79. Unusually high frequencies of HIV-specific cytotoxic T lymphocytes in humans
80. Human T-lymphotropic virus I-infected T cells constitutively express lymphotoxin in vitro
81. + T cell function by the HIV envelope protein, gp120
82. Inhibitory influences of envelope glycoproteins of HIV-1 on normal immune responses
83. Blocking of infectivity and immunosuppression by an HIV envelope-derived synthetic peptide
84. Inhibition of functional properties of tetanus antigen-specific T-cell clones by envelope glycoprotein gp120 of human immunodeficiency virus
85. Sequence homology between acquired immunodeficiency syndrome virus envelope protein and interleukin 2
86. Functional interaction and partial homology between human immunodeficiency virus and neuroleukin
87. Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide
88. HIV-1 and its envelope glycoprotein down-regulate chemotactic ligand receptors and chemotactic function of peripheral blood monocytes
89. Biological activities residing in the Fe region of immunoglobulin
90. “Tuftsin”: A natural phagocytosis stimulating peptide
91. The effect of Tuftsin on the nitrous blue tetrazolium reduction of normal human polymorphonuclear leukocytes
92. Regulatory role of a tripeptide (TKP) from the second constant domain of immunoglobulin G-I: Inhibition of rat and human macrophage activities
93. Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens
94. The gp120-CD4 interface: Structural, immunological and pathological considerations
95. A comprehensive set of sequence analysis programs for the VAX
96. Molecular mimicry and autoimmune disease
97. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity
98. Neutralization of HIV isolates by anti-idiotypic antibodies which mimic the T4 (CD4) epitope: A potential AIDS vaccine
99. Molecular mimicry and autoimmune disease
100. Hypothesis: AIDS is an autoimmune disease directed at the immune system and triggered by a lymphotropic retrovirus
101. Identification of homologous regions in human immunodeficiency virus I gp41 and human MHC class II β1 domain. I. Monoclonal antibodies against the gp41-derived peptide and patients' sera react with native HLA class II antigens, suggesting a role for autoimmunity in the pathogenesis of acquired immune deficiency syndrome
102. Common epitope in human immunodeficiency virus (HIV) I-GP41 and HLA class II elicits immunosuppressive autoantibodies capable of contributing to immune dysfunction in HIV I-infected individuals
103. HIV and HLA similarity
104. + effector cells armed in vivo with cytophilic antibody
105. Distribution of antibodies against denatured collagen in AIDS risk groups and homosexual AIDS patients suggests a link between autoimmunity and the immunopathogenesis of AIDS
106. A model for the selective loss of major histocompatibility complex self-restricted T cell immune responses during the development of acquired immune deficiency syndrome (AIDS)
107. T cell interactions in autoimmunity: Insights from a murine model of graft-versus-host disease
108. AIDS: A syndrome of immune dysregulation, dysfunction, and deficiency
109. The CD4 molecule, the human immunodeficiency virus and anti-idiotypic antibodies
110. Epitopes of the CD4 antigen and HIV infection
111. Thymosin α1 and thymosin β4 in serum: Comparison of normal, cord, homosexual and AIDS serum
112. Neutralization of HTLV-III/LAV replication by antiserum to thymosin α1
113. Human immunodeficiency virus contains an epitope immunoreactive with thymosin α1 and the 30-amino acid synthetic p17 group-specific antigen peptide HGP-30
114. Antiviral antibodies in HIV (HTLV-III) infection possess autoantibody activity against a CH1 domain determinant in human IgG: Possible immunological consequences
115. Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization
116. The reservoir for HIV-1 in human peripheral blood is a T cell that maintains expression of CD4
117. Effects of cyclosporin on T-cell subsets in human immunodeficiency virus disease