Detection of apoptosis of immature CD4+8+ thymocytes by flow cytometry

Journal of Immunological Methods

Volumn 137, Issue 1, 1991, Pages 79-87

  Swat, Wojciech ^a   Ignatowicz, Leszek ^a   Kisielow, Pawel ^a  

^a INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

Author keywords

Apoptosis; CD4+8+ thymocyte; Flow cytometry

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; FLOW CYTOMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; THYMOCYTE;

ANIMAL; ANTIGENS, CD; ANTIGENS, CD4; ANTIGENS, CD8; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELL LINE; CELL SURVIVAL; DNA; FLOW CYTOMETRY; HYDROCORTISONE; MICE; MICE, INBRED BALB C; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTE SUBSETS;

ANIMALIA;

EID: 0025964265     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-1759(91)90396-W     Document Type: Article

References (16)

1. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand
2. Macrophages phagocytose thymic lymphocytes with productively rearranged T cell receptor alpha and beta genes
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4. Selective development of CD4 T cell in transgenic mice expressing a class II MHC-restricted antigen receptor
5. Negative and positive selection of immature thymocytes: timing and the role of the ligand for alpha/beta T cell receptor
6. + thymocytes
7. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
8. Antibodies against the T cell receptor/CD3 complex interfere with distinct intra-thymic cell-cell interactions in vivo: correlation with arest of T cell differentiation
9. Selective elimination of double-positive immature thymocytes by a thymic epithelial cell Une
10. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
11. The generation of mature T cells requires interaction of the alpha/beta T cell receptor with major histocompatibility antigens
12. Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice
13. Positive and negative selection of an antigen receptor on T cells in transgenic mice
14. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures
15. Apoptosis
16. Hormone-induced cell death. Purification and properties of thymocytes undergoing apoptosis after glucocorticoid treatment