Determination of the in vivo antigen-antibody affinity constant from the redistribution of desipramine in rats following administration of a desipramine-specific monoclonal antibody

Biochemical Pharmacology

Volumn 41, Issue 3, 1991, Pages 473-476

  Pond, Susan M ^a   Pentel, Paul R ^b   Keyler, Daniel E ^b   Winzor, Donald J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b Hennepin Country Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESIPRAMINE; MONOCLONAL ANTIBODY;

ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; DESIPRAMINE; MALE; MATHEMATICS; RATS; REGRESSION ANALYSIS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025964096     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(91)90552-G     Document Type: Article

References (11)

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6. Determination of free fractions of tricyclic antidepressants
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10. Pharmacokinetics and toxicity of high doses of antibody Fab fragments in rats