Freshly isolated or cryopreserved human hepatocytes in primary culture: Influence of drug metabolism on hepatotoxicity

Toxicology in Vitro

Volumn 5, Issue 5-6, 1991, Pages 483-486

  de Sousa, G ^a   Dou, M ^a   Barbe, D ^a   Lacarelle, B ^a   Placidi, M ^a   Rahmani, R ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; MITOXANTRONE;

CONFERENCE PAPER; CRYOPRESERVATION; DRUG METABOLISM; HUMAN; HUMAN CELL; LIVER CELL CULTURE; LIVER TOXICITY; PRIORITY JOURNAL;

ANIMALIA;

EID: 0025953527     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/0887-2333(91)90077-Q     Document Type: Article

References (15)

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8. Characterization of midazolam metabolism using human hepatic microsomal fractions and hepatocytes in suspension obtained by perfusion of a whole human liver
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13. Extrapolation of preclinical pharmacokinetic data to therapeutic drug use
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15. Mitoxantrone: a new anticancer drug with significant activity