Prodrugs of peptides. 15. 4-Imidazolidinone prodrug derivatives of enkephalins to prevent aminopeptidase-catalyzed metabolism in plasma and absorptive mucosae

International Journal of Pharmaceutics

Volumn 76, Issue 1-2, 1991, Pages 113-122

  Rasmussen, Gitte Juel ^a   Bundgaard, Hans ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

4 Imidazolidinone; Aminopeptidase; Enkephalin; Hydrolysis; Lipophilicity; Peptide; Prodrug

Indexed keywords

4 IMIDAZOLIDINONE DERIVATIVE; AMINOPEPTIDASE; ENKEPHALIN DERIVATIVE; LEUCINE ENKEPHALIN; METENKEPHALIN; PEPTIDE; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; DRUG DEGRADATION; DRUG STABILITY; DRUG STRUCTURE; HYDROLYSIS; LIPOPHILICITY; PH; PRIORITY JOURNAL;

EID: 0025949443     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(91)90349-S     Document Type: Article

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