Increase in metallothionein produced by chemicals that induce oxidative stress

Toxicology and Applied Pharmacology

Volumn 110, Issue 2, 1991, Pages 347-354

  Bauman, J W ^a   Liu, J ^a   Liu, Y P ^a   Klaassen, C D ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DIAMIDE; DIQUAT; DOXORUBICIN; MALEIC ACID DIETHYL ESTER; MENADIONE; METALLOTHIONEIN; METRONIDAZOLE; PARAQUAT; PHORONE; SKATOLE; TERT BUTYL HYDROPEROXIDE;

ANIMAL EXPERIMENT; ARTICLE; HEART; INTESTINE; KIDNEY; LIVER; LUNG; MALE; MOUSE; NONHUMAN; OXIDATION; PANCREAS; PRIORITY JOURNAL; SPLEEN; STRESS; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMAL; CISPLATIN; CYTOSOL; DIAMIDE; DIQUAT; DOXORUBICIN; KETONES; LIVER; MALE; MALEATES; METALLOTHIONEIN; METRONIDAZOLE; MICE; MICE, INBRED STRAINS; ORGAN SPECIFICITY; PARAQUAT; PEROXIDES; SKATOLE; SUPPORT, U.S. GOV'T, P.H.S.; TERT-BUTYLHYDROPEROXIDE; VITAMIN K;

ANIMALIA;

EID: 0025944389     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/S0041-008X(05)80017-1     Document Type: Article

References (38)

1. Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein
2. Stimulation of peroxidation in rat liver microsomes by (copper, zinc)-metallothioneins
3. Radioresistance in cells with high content of metallothionein
4. A hypothesis regarding the protective role of metallothioneins against the toxicity of DNA interactive anticancer drugs
5. Altered thiol and calcium homeostasis in oxidative hepatocellular injury
6. Effect of epinephrine and norepinephrine on zinc thionein levels and induction in rat liver
7. Involvement of metallothionein in the hepatic metabolism of copper
8. Protection of carbon tetrachloride-induced hepatotoxicity by zinc: Role of metallothionein
9. Metallothionein
10. Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues
11. Metallothionein induction in mouse tissues by cis-dichlorodiammineplatinum (II) and its hydrolysis products
12. Metallothionein-like proteins and cell resistance to cis-dichlorodiammineplatinum (II) in L1210 cells
13. Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells
14. Zinc-induced tolerance to cadmium hepatoxicity
15. Oxidants and human disease: some new concepts
16. Cross-tolerance to hyperoxia following cadmium aerosol pretreatment
17. Overexpressed human metallothionein IIA gene protects chinese hamster ovary cells from killing alkylating agents
18. Metallothionein mRNA induction in HeLa cells in response to zinc or dexamethasone is a primary induction response
19. Interleukin 1 regulates human metallothionein gene expression
20. Overexpression of metallothionein confers resistance to anticancer drugs
21. Organ-specific metallothionein induction in mice by x irradiation
22. Spin-trapping of free radicals formed during in vitro and in vivo metabolism of 3-methylindole
23. Extents of hepatic zinc-thionein induction in mice given equimolar dose of various heavy metals
24. Promotion of radioresistance by metallothionein induction prior to irradiation
25. Cytotoxicity of an organic hydroperoxide and cellular antiuoxidant defense system against hydroperoxides in cultured mammalian cells
26. Biological function of metallothionein. V. Its induction in rats by various stresses
27. A simplified procedure for determination of metallothionein in animal tissues
28. Chemical depletion of glutathione in vivo
29. Tissue uptake of paraquat and diquat
30. Metallothionein-I accumulation in the rat lung following a single paraquat administration
31. Kidney synthesizes less metallothionein than liver in response to cadmium chloride and cadmium-metallothionein
32. Increased metallothionein content in rat liver induced by x irradiation and exposure to high oxygen tension
33. Oxidative stress: Quinone redox cycling
34. Stimulatory effect of cisplatin on production of lipid peroxidation in renal tissues
35. Inhibition of cell membrane lipid peroxidation by cadmium- and zinc-metallothioneins
36. Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals
37. Concentration of metallothionein in major organs of rats after administration of various metals