The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

Cell

Volumn 66, Issue 3, 1991, Pages 451-464

  Woods, Daniel F ^a   Bryant, Peter J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANYLATE KINASE; PROTEIN TYROSINE KINASE;

ANIMAL TISSUE; ARTICLE; DROSOPHILA; EMBRYO; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; CELL ADHESION; CELL COMPARTMENTATION; CELL DIVISION; CELL MEMBRANE; CLONING, MOLECULAR; DNA; DROSOPHILA MELANOGASTER; EPITHELIAL CELLS; GENE EXPRESSION; GENES, TUMOR SUPPRESSOR; INSECT HORMONES; MOLECULAR SEQUENCE DATA; NUCLEOSIDE-PHOSPHATE KINASE; RESTRICTION MAPPING; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPPORT, U.S. GOV'T, NON-P.H.S.;

ANIMALIA;

EID: 0025941465     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(81)90009-X     Document Type: Article

References (75)

1. Binding of myosin I to membrane lipids
2. The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins
3. Guanylate kinase from Saccharomyces cerevisiae
4. A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase
5. Expression of an activated ras gene causes developmental abnormalities in transgenic Drosophila melanogaster
6. Ras oncogenes in human cancer: a review
7. The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway
8. Giant and duplicated imaginal discs in a new lethal mutant of Drosophila melanogaster
9. Mutations at the fat locus interfere with cell proliferation control and epithelial morphogenesis in Drosophila
10. The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
11. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
12. Developmental consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis
13. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
14. Proteins shifting from the cytoplasm into the nucleus during early development of Drosophila melanogaster
15. Assembly of the mitochondrial membrane system
16. Genetic characterization of Bordetella pertussis filamentous haemagglutinin: a protein processed from an unusually large precursor
17. Yeast actin-binding proteins: evidence for a role in morphogenesis
18. Homology of a yeast actin-binding protein to signal transduction proteins and myosin-1
19. Intercellular junctions during development and in tissue cultures of Drosophila melanogaster: an electron microscopic study
20. Identification of a chromosome 18q gene that is altered in colorectal cancers
21. Tumor-suppressor genes of Drosophila melanogaster
22. Developmental capacities of benign and malignant neoplasms of Drosophila
23. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping
24. The complete DNA sequence of vaccina virus
25. Purification and properties of guanylate kinase from bovine retinas and rod outer segments
26. Isolation and characterization of temperature-sensitive lethal(2)giant larva alleles. II. Temperature-sensitive expression of the imaginal disc neoplasm
27. Studies on the development and maintenance of epithelial cell surface polarity with monoclonal antibodies
28. Retinoblastoma growth suppressor and a 300-kDa protein appear to regulate cellular DNA synthesis
29. N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl
30. Cell transformation by the viral src oncogene
31. The heavy chain of Acanthamoeba myosin IB is a fusion of myosin-like and non-myosin-like sequences
32. Defective gap-junctional communication associated with imaginal disc overgrowth and degeneration caused by mutations of the dco gene in Drosophila
33. The Drosophila melanogaster l(2)gl gene encodes a protein in the cadherin cell-adhesion molecule family
34. p53: oncogene or antioncogene?
35. Clues to the function of Nm23/Awd in tumor metastasis, development and signal transduction provided by studies of the slime mold (Dictyostelium discoideum)
36. Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease
37. The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T
38. Tumor suppressor genes
39. The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21
40. Direct determination of the growth rate of Drosophila imaginal discs
41. ha1 a polyphasic, temperature-sensitive mutant of Drosophila melanogaster with a variety of imaginal disc defects
42. A novel viral oncogene with structural similarity to phospholipase C
43. Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae
44. Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster
45. Molecular action of the l(2)gl tumor suppressor gene of Drosophila melanogaster
46. Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction
47. Cell death and autonomous gene action in lethals affecting imaginal discs in Drosophila melanogaster
48. Septate and scalariform junctions in arthropods
49. Non-catalytic domains of cytoplesmic proteintyrosine kinases: regulatory elements in signal transduction
50. Improved tools for biological sequence comparison
51. The maternal effect of lethal(1)discs-large-1: a recessive oncogene of Drosophila melanogaster
52. Clonal analysis of the tissue specificity of recessive female-sterile mutations in Drosophila melanogaster using a dominant female-sterile mutation fs(1)K1237
53. Redistribution of surface macromolecules in dissociated epithelial cells
54. Inherited predisposition to cancer
55. The ultrastructure of the developing leg of Drosophila melanogaster
56. Control of the developmental timer for Drosophila pupariation
57. Activation of pp60c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90–95
58. Fibrillar collagen genes
59. Similarity in membrane proteins
60. Morphogenesis of the polarized epithelial cell phenotype
61. Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis
62. Sequence similarity of phospholipase C with the non-catalytic region of src
63. Three-dimensional structure of the complex of guanylate with its substrate GMP
64. The recovery and preliminary characterization of X chromosome mutants affecting imaginal discs of Drosophila melanogaster
65. Molecular cloning of two types of GAP complementary DNA from human placenta
66. Two genes required for cell fusion during yeast conjugation: evidence for a pheromoneinduced surface protein
67. Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium
68. Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients
69. Primary structure of the brain α-spectrin
70. Studies on an epithelial (gland) cell junction
71. opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster
72. Molecular cloning of the lethal (1)discs large-1 oncogene of Drosophila
73. The neurofibromatosis type 1 gene encodes a protein related to GAP
74. The catalytic domain of the neurotibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae
75. Redistribution of membrane proteins in isolated mouse intestinal epithelial cells