Identification and characterization of the familial adenomatous polyposis coli gene

Cell

Volumn 66, Issue 3, 1991, Pages 589-600

  Groden, Joanna ^a   Thliveris, Andrew ^a,b   Samowitz, Wade ^a   Carlson, Mary ^a   Gelbert, Lawrence ^a,b   Albertsen, Hans ^a   Joslyn, Geoff ^a,b   Stevens, Jeff ^a,b   Spirio, Lisa ^a   Robertson, Margaret ^a,b   Sargeant, Leslie ^a,b   Krapcho, Karen ^a,b   Wolff, Erika ^a,b   Burt, Randall ^a   Hughes, J P ^c   Warrington, Janet ^d   McPherson, John ^d   Wasmuth, John ^d   Le Paslier, Denis ^e   Abderrahim, Hadi ^e   Cohen, Daniel ^e   Leppert, Mark ^a,b   White, Ray ^a,b   more..

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c St Mark's Hospital Salt Lake City   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e FONDATION JEAN DAUSSET CEPH   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COLON ADENOMA; DNA SEQUENCE; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; AMINO ACID SEQUENCE; BASE SEQUENCE; CHROMOSOME DELETION; DNA; EXONS; GENES, STRUCTURAL; HUMAN; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDES; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM (GENETICS); RESTRICTION MAPPING; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025938038     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(81)90021-0     Document Type: Article

References (28)

1. Restriction sites containing CpG show a higher frequency of polymorphism in human DNA
2. Localization of the gene for familial adenomatous polyposis on chromosome 5
3. Consider the coiled coil
4. Dominant inheritance of adenomatous colonic polyps and colorectal cancer
5. Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers
6. Genetic origin of mutations predisposing to retinoblastoma
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8. Single-step method of RNA isolation by acid guanidinium thiocyante-phenol-chloroform extraction
9. α-Helical coiled coils — a widespread motif in proteins
10. Multiple mutations in highly conserved residues are found in mildly affected cystic fibrosis patients
11. Identification of a chromosome 18q gene that is altered in colorectal cancers
12. Brief clinical report: Gardner syndrome in a man with an interstitial deletion of 5q
13. Identification of deletion mutations and three new genes at the familial polyposis locus
14. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers
15. Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma
16. A simple method for displaying the hydropathic character of a protein
17. Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps
18. Amplification of flanking sequences by inverse PCR
19. Loss of constitutional heterozygosity in colon carcinoma from patients with familial polyposis coli
20. Detection of polymorphisms of human DNA by gel electrophoresis as single strand conformation polymorphisms
21. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
22. A constitutional 5q23 deletion
23. DNA sequencing with chain-terminating inhibitors
24. Chromosome 5 allele loss in human colorectal carcinomas
25. Genetic alterations during colorectal tumor development
26. Sulindac for polyposis of the colon