Patterns of divergence in homologous proteins as indicators of secondary and tertiary structure: A prediction of the structure of the catalytic domain of protein kinases

Advances in Enzyme Regulation

Volumn 31, Issue C, 1991, Pages 121-181

  Benner, Steven A ^a   Gerloff, Dietlinde ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE;

ANIMAL; BINDING SITE; CHEMISTRY; COMPARATIVE STUDY; GENETIC VARIABILITY; GENETICS; HUMAN; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; REVIEW; SEQUENCE HOMOLOGY;

ANIMAL; BASE SEQUENCE; BINDING SITES; COMPARATIVE STUDY; HUMAN; PROTEIN CONFORMATION; PROTEIN KINASES; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; VARIATION (GENETICS);

EID: 0025935158     PISSN: 00652571     EISSN: None     Source Type: Journal    
DOI: 10.1016/0065-2571(91)90012-B     Document Type: Article

References (35)

1. The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
2. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
3. cAMP-dependent protein kinase: Model for an enzyme family
4. Patterns of divergence in homologous proteins as indicators of tertiary and quaternary structure
5. Evolution and structural theory The frontier between chemistry and biochemistry
6. Deciphering the protein folding code
7. The relationship between the divergence of sequence and structure in proteins
8. Prediction of surface loops of protein-folds from multiple alignments of homologous sequences
9. Turn prediction in proteins using a pattern-matching approach
10. Anatomy and taxonomy of proteins
11. Crystallization of cAMP-dependent protein kinase. Crystals of catalytic subunit diffract to 3.5 Å resolution
12. Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase
13. Prediction of evolutionary structure by evolutionary comparison: Application to the alpha subunit of tryptophan synthase
14. Multiple RNA species code for the catalytic subunit of cAMP-dependent protein kinase from LLC-PK 1 cells
15. Selective modification of the catalytic subunit of cAMP-dependent protein kinase with sulfhydryl-specific fluorescent probes
16. Secondary structure assignment for alpha/beta proteins by a combinatorial approach
17. On the conformation of proteins: An analysis of beta-pleated sheets
18. Predicted nucleotide-binding properties of p21 protein and its cancer-associated variant
19. Modelling the ATP-binding site of oncogene products, the epidermal growth factor receptor and related proteins
20. Differential labeling of the catalytic subunit of cAMP-dependent protein kinase with acetic anhydride: Substrate-induced conformational changes
21. Affinity labeling of cAMP-dependent protein kinase with p-fluorosulfonylbenzoyladenosine
22. Identification of aspartate-184 as an essential residue in the catalytic subunit of cAMP-dependent protein kinase
23. Differential labeling of the catalytic subunit of cAMP-dependent protein kinase with a water-soluble carbodiimide: Identification of carboxyl groups protected by MgATP and inhibitor peptides
24. Probing the peptide binding site of the cAMP-dependent protein kinase by using a peptide-based photoaffinity label
25. Identification of the peptide recognition site in the catalytic subunit of cAMP-dependent protein kinase
26. Dicyclohexylcarbodiimide cross-links two conserved residues, Asp-184 and Lys-72, at the active site of the catalytic subunit of cAMP-dependent protein kinase
27. Identification of amino acid residues involved in substrate recognition by the catalytic subunit of bovine cyclic AMP dependent protein kinase: Peptide-based affinity labels
28. Modification of the catalytic subunit of bovine heart cAMP dependent protein kinase with affinity labels related to peptide substrates
29. Differential labeling and identification of the cysteine-containing tryptic peptides of the catalytic subunit of porcine heart cAMP-dependent protein kinase
30. Sequence, structure, and activity of phosphoglycerate kinase: a possible hinge-bending enzyme
31. Crystal structure of the complex of phosphofructokinase from Escherichia coli with its reaction products
32. Refined structure of porcine cytosolic adenylate kinase at 2.1 Å resolution
33. The structure of cat muscle pyruvate kinase
34. Near- and far-ultraviolet circular dichroism of the catalytic subunit of adenosine cyclic 5′-monophosphate dependent protein kinase