[3H]CGP 39653: a new N-methyl-D-aspartate antagonist radioligand with low nanomolar affinity in rat brain

European Journal of Pharmacology

Volumn 192, Issue 1, 1991, Pages 19-24

  Sills, Matthew A ^a   Fagg, Graham ^a   Pozza, Mario ^a   Angst, Christof ^a   Brundish, Derek E ^a   Hurt, Stephen D ^a   Jay Wilusz, E ^a   Williams, Michael ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Excitatory amino acid; L Glutamate; NMDA (N methyl D aspartate)

Indexed keywords

2 AMINO 4 PHOSPHONOBUTYRIC ACID; 2 AMINO 4 PHOSPHONOMETHYL 3 HEPTENOIC ACID; 4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; 4 PHOSPHONOMETHYLPIPECOLIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMINO ACID DERIVATIVE; DEXOXADROL; GLUTAMIC ACID; GLUTAMIC ACID DIETHYL ESTER; GLYCINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RADIOLIGAND; TENOCYCLIDINE; 1 (1 (2 THIENYL)CYCLOHEXYL)PIPERIDINE; 1-(1-(2-THIENYL)CYCLOHEXYL)PIPERIDINE; 2 AMINO 5 PHOSPHONOVALERIC ACID; DRUG DERIVATIVE; GLUTAMIC ACID DERIVATIVE; PHENCYCLIDINE; RECEPTORS, N METHYL D ASPARTATE;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BRAIN CORTEX; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG CONCENTRATION; DRUG RECEPTOR BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BRAIN; DRUG EFFECT; IN VITRO STUDY; KINETICS; METABOLISM; RAT STRAIN;

2-AMINO-5-PHOSPHONOVALERATE; ANIMAL; BRAIN; CEREBRAL CORTEX; GLUTAMATES; GLUTAMIC ACID; IN VITRO; KINETICS; MALE; PHENCYCLIDINE; RATS; RATS, INBRED STRAINS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0025924039     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(91)90063-V     Document Type: Article

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