Melanogenesis: a realistic target for antimelanoma therapy?

European Journal of Cancer and Clinical Oncology

Volumn 27, Issue 9, 1991, Pages 1172-1177

  Riley, P A ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE DERIVATIVE; PRODRUG;

DRUG DESIGN; DRUG MECHANISM; HUMAN; MELANOGENESIS; MELANOMA; PRIORITY JOURNAL; REVIEW;

ANTINEOPLASTIC AGENTS; HUMAN; MELANINS; MELANOCYTES; MELANOMA; MOLECULAR STRUCTURE;

EID: 0025916156     PISSN: 02775379     EISSN: None     Source Type: Journal    
DOI: 10.1016/0277-5379(91)90319-9     Document Type: Article

References (75)

1. Structure, chemistry and biosynthesis of the melanins
2. The mechanism of melanogenesis
3. Ueber den Mechanismus der Chinonreaktionen
4. Biochemistry at 100°C: explosive secretory discharge of bombadier beetles
5. On the hardening of the cuticle of insects
6. Analysis of mammalian pigmentation at the molecular level
7. Histochemical demonstration of melanocytes by the use of 5,6 diacetoxyindole as substrate for tyrosinase
8. Mammalian tyrosinase catalyses three reactions in the biosynthesis of melanin
9. Early steps in the free radical polymerization of 34 dihydroxyphenylalanine
10. The aerobic oxidases
11. Oxidases
12. Dopachrome oxido-reductase: a new enzyme in the pigment pathway
13. Function of dopachrome oxidoreductase and metal ions in dopachrome conversion in the eumelanin pathway
14. Dopachrome conversion factor functions as an isomerase
15. Regulation of mammalian melanogenesis I: partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase
16. The chemistry of melanin: 5. Oxidation of dihydroxyphenylalanine by tyrosinase
17. Effect of metal ions on the rearrangement of dopachrome
18. 3
19. A pulse radiolysis investigation of the oxidation of indolic melanin precursors: evidence for indolequinones and subsequent intermediates
20. A pulse radiolysis investigation of the oxidation of methoxylated metabolites of indolic precursors
21. o-Quinone/quinone methide isomerase: a novel enzyme preventing the destruction of self-matter by phenol-oxidase-generated quinones during immune response in insects
22. 4-Alkyl-O-Quinone/2-hydroxy-p-quinone methide isomerase from the larvae hemolymph of Sarcophaga bullata
23. Quinone methide sclerotization: a revised mechanism for β-sclerotization of insect cuticle
24. Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus
25. A cDNA encoding tyrosinase-related protein maps to the brown locus in mouse
26. Nucleotide sequence of the cDNA encoding human tyrosinase-related protein
27. The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product
28. Isolation of Oligomers of 5,6-Dihydroxyindole-2-carboxylic acid from the eye of the catfish
29. Progress in the chemistry of melanins and related metabolites
30. Electron microscopy of melanocytes: the fine structure of hair bulb premelanosomes
31. Melanin-related biochemistry of ICR 1 human melanoma cells
32. Recent advances in the chemistry of melanogenesis in mammals
33. Modulation of glutathione level in cultured human melanoma cells
34. Dopaquinone and addition products in cultured human melanoma cells
35. Identification of three indolic compounds in a pigmented melanoma cell-culture supernatant by gas chromatography-mass spectrometry
36. Determination of catechol-O-methyl transferase in relation to melanin metabolism with HPLC and fluorimetric detection
37. Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity
38. Malignant melanoma: changing trends in factors influencing survival from 1964–1982
39. Malignant melanoma
40. Human melanoma targeting with α-MSH-melphalan conjugate
41. Saporin 6 conjugated to monoclonal antibody selectively kills human melanoma cells
42. Melanin-affinic thioureas as selective melanoma seekers
43. 10B molecule-melanoma cell interaction from in vitro to first clinical trial
44. Hydroxyanisole depigmentation: in vivo studies
45. Hydroxyanisole depigmentation: in vitro studies
46. Mechanism of pigment cell toxicity produced by hydroxyanisole
47. Electron spin resonance studies of reactive intermediates of tyrosinase oxidation of hydroxyanisole
48. Radicals and Melanomas
49. On the interaction of anisyl-3,4-semiquinone with oxygen
50. Reaction Kinetics of 4-methoxyortho-benzoquinone in relation to its mechanism of cytotoxicity: a pulse radiolysis study
51. An experimental approach to the chemotherapy of melanoma
52. Intracellular activation of τ-L-glutamyl-4-hydroxybenzene by tyrosinase, a mechanism for selective cytotoxicity against melanocarcinoma
53. Agents with potential specificity against melanotic melanoma
54. Structure-activity relationship defining the cytotoxicity of catechol analogues against human malignant melanoma
55. Preparation and antimelanoma activity of hydroquinone monoalkyl ethers
56. Melanocytotoxicity and antimelanoma effects of phenolic amine compounds in mice in vivo
57. Modification of dopa toxicity in human tumour cells
58. Mechanism of antitumoural activity of catechols in culture
59. Ribonucleotide reductase in melanoma tissue: EPR detection in human amelanotic melanoma and quenching of the tyrosine radical by 4-hydroxyanisole
60. Effect of parahydroxyanisole on tyrosinase and mitochondrial oxidoreductase
61. Inhibition of DNA synthesis and S-phase killing by 4-hydroxyanisole
62. Surface alterations of 3T3 fibroblasts and exposed to 4-hydroxyanisole
63. The role of substituted anisoles in epidermal microinvasion
64. Metabolism of 4-hydroxyanisole: identification of major urinary excretory products
65. 4-Hydroxyanisole: Human Pharmacokinetics
66. Treatment of malignant melanoma by intravascular 4-hydroxyanisole
67. A phase I study of 4-hydroxyanisole (4-HOA) in patients with advanced malignant melanoma
68. Recent results of a clinical pilot study of intra-arterial 4HA chemotherapy in malignant melanoma
69. Effects of tyrosinase activity on the cytotoxicity of 3,4 dihydroxybenzylamine and Buthionine Sulfoximine in Human Melanoma Cells