Telomerase is processive

Molecular and Cellular Biology

Volumn 11, Issue 9, 1991, Pages 4572-4580

  Greider, Carol W ^a  

^a Cold Spring Harbor Laboratory ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGODEOXYNUCLEOTIDE; PRIMER DNA; TELOMERASE;

ARTICLE; DNA SEQUENCE; DNA TEMPLATE; NONHUMAN; PRIORITY JOURNAL; TETRAHYMENA;

ANIMAL; BASE SEQUENCE; DNA NUCLEOTIDYLEXOTRANSFERASE; DNA, PROTOZOAN; ELECTROPHORESIS, AGAR GEL; KINETICS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; REPETITIVE SEQUENCES, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TEMPLATES, GENETIC; TETRAHYMENA;

TETRAHYMENA;

EID: 0025914141     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.11.9.4572     Document Type: Article

References (29)

1. Blackburn, E. H., C. W. Greider, E. Henderson, M. Lee, J. Shampay, and D. Shippen-Lentz. 1989. Recognition and elongation of telomeres by telomerase. Genome 31:553-560.
2. Blackburn, E. H., and J. W. Szostak. 1984. The molecular structure of centromeres and telomeres. Annu. Rev. Biochem. 53:163-194.
3. Bryant, F. R., K. A. Johnson, and S. J. Benkovic. 1983. Elementary steps in the DNA polymerase I reaction pathway. Biochemistry 22:3537-3546.
4. Cha, T.-A., and B. M. Alberts. 1988. In T. Kelly and B. Stillman (ed.), Cancer cells 6: eukaryotic DNA replication. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
5. Forney, J., E. R. Henderson, and E. H. Blackburn. 1987. Identification of the telomeric sequence of the acellular slime molds Didymium iridis and Physarum polycephalum. Nucleic Acids Res. 15:9143-9152.
6. Greider, C. W., and E. H. Blackburn. 1985. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43:405-413.
7. Greider, C. W., and E. H. Blackburn. 1987. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 51:887-898.
8. Greider, C. W., and E. H. Blackburn. 1989. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature (London) 337:331-337.
9. 8a. Harrington, L. A., and C. W. Greider. Unpublished data.
10. Henderson, E. R., C. Hardin, S. Wolk, I. Tinoco, and E. H. Blackburn. 1987. Telomeric DNA oligonucleotides form novel intramolecular structures containing guanine-guanine base pairs. Cell 51:899-908.
11. Henderson, E. R., and E. H. Blackburn. 1989. An overhanging 3′ terminus is a conserved feature of telomeres. Mol. Cell. Biol. 9:345-348.
12. Johnston, R. F., S. C. Pickett, and D. L. Barker. 1990. Autoradiography using storage phosphor technology. Electrophoresis 11:355-360.
13. Kornberg, A. 1980. DNA replication. W. H. Freeman and Co., San Francisco.
14. Larson, D. D., E. A. Spangler, and E. H. Blackburn. 1987 Dynamics of telomere length variation in Tetrahymena thermophila. Cell 50:477-183.
15. Lundblad, V., and E. H. Blackburn. 1990. RNA-dependent polymerase motifs in EST1: tentative identification of a protein component of an essential yeast telomerase. Cell 60:529-530.
16. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory. Cold Spring Harbor, N.Y.
17. McHenry, C. S. 1988. DNA polymerase III holoenzyme of Escherichia coli. Annu. Rev. Biochem. 57:519-550.
18. Morin, G. 1989. The human telomere terminal transferase is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59: 521-529.
19. Prelich, G., C.-T. Tan, M. Kostura, M. B. Mathews, A. G. So, K. M. Downey, and B. Stillman. 1987. Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein. Nature (London) 326:517-520.
20. Shippen-Lentz, D., and E. H. Blackburn. 1989. Telomere terminal transferase activity from Euplotes crassus adds large numbers of TTTTGGGG repeats onto telomeric primers. Mol. Cell. Biol. 9:2761-2764.
21. Shippen-Lentz, D., and E. H. Blackburn. 1990. Functional evidence for an RNA template in telomerase. Science 247:546-552.
22. Tsurimoto, T., and B. Stillman. 1989. Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases α and δ. EMBO J. 8:3883-3889.
23. Tsurimoto, T., and B. Stillman. 1990. Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4. Proc. Natl. Acad. Sci. USA 87:1023-1027.
24. Varmus, H., and R. Swanstrom. 1984. Replication of retroviruses, p. 369-512. In R. Weiss, N. Teich, H. Varmus, and J. Coffin (ed.), RNA tumor viruses. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
25. von-Hippel, P. H., J. W. Newport, P. S. Leland, F. R. Fairfield, J. W. Hockensmith, and M. K. Dolejsi. 1983. Dynamic and structural interactions in the T4 DNA replication complex, p. 153-171. In N. R. Cozzarelli (ed.), Mechanisms of DNA replication and recombination. Alan R. Liss, Inc., New York.
26. Williamson, J. R., M. K. Raghuraman, and T. R. Cech. 1989. Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell 59:871-880.
27. Yu, G.-L., J. D. Bradley, L. D. Attardi, and E. H. Blackburn. 1990. In vivo alteration of telomere sequences and senescence caused by mutated telomerase RNAs. Nature (London) 344:126-132.
28. Zahler, A. M., and D. M. Prescott. 1988. Telomere terminal transferase activity in the hypotrichous ciliate Oxytricha nova and a model for replication of the ends of linear DNA molecular Nucleic Acids Res. 16:6953.
29. Zahler, A. M., J. R. Williamson, T. R. Cech, and D. M. Prescott. 1991. Inhibition of telomerase by G-quartet DNA structures. Nature (London) 350:718-720.