Quantitative Structure-Activity Relationships of Antitumor Guanidinothiazolecarboxamides with Survival Enhancement for Therapy in the 3LL Lewis Lung Carcinoma Model

Journal of Medicinal Chemistry

Volumn 34, Issue 7, 1991, Pages 1975-1982

  Schnur, Rodney C ^a   Gallaschun, Randall J ^a   Singleton, David H ^a   Grissom, Martin ^a   Sloan, Donald E ^a   Goodwin, Peter ^a   McNiff, Patricia A ^a   Fliri, Anton F J ^a   Mangano, F Michael ^a   Olson, Thanh H ^a   Pollack, Vincent A ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 GUANIDINO 4 THIAZOLECARBOXAMIDE DERIVATIVE; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; N (5 FLUORO 2 BENZOTHIAZOLYL) 2 GUANIDINO 4 THIAZOLECARBOXAMIDE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; LEWIS CARCINOMA; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ADENOCARCINOMA; ANIMAL; ANTINEOPLASTIC AGENTS; CHEMISTRY; FEMALE; GUANIDINES; LUNG NEOPLASMS; MICE; MODELS, BIOLOGICAL; NEOPLASMS, EXPERIMENTAL; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 0025909218     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00111a009     Document Type: Article

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