PMN-elastase in comparison with CRP, antiproteases, and LDH as indicators of necrosis in human acute pancreatitis

Pancreas

Volumn 6, Issue 3, 1991, Pages 253-259

  Uhl, Waldemar ^a   Büchler, Markus ^a   Malfertheiner, Peter ^a   Martini, Markus ^a   Beger, Hans G ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Antiproteases; C reactive protein; Indicators of necrosis; Lactate dehydrogenase; Pancreatitis; PMN elastase

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALPHA 2 MACROGLOBULIN; C REACTIVE PROTEIN; ELASTASE; LACTATE DEHYDROGENASE;

ACUTE PANCREATITIS; ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NECROSIS; NEUTROPHIL; PRIORITY JOURNAL;

ACUTE DISEASE; ADULT; AGED; AGED, 80 AND OVER; ALPHA 1-ANTITRYPSIN; ALPHA-MACROGLOBULINS; C-REACTIVE PROTEIN; COMPARATIVE STUDY; FEMALE; HUMAN; KINETICS; LACTATE DEHYDROGENASE; MALE; MIDDLE AGE; NECROSIS; NEUTROPHILS; PANCREATIC ELASTASE; PANCREATITIS; PROGNOSIS; PROTEASE INHIBITORS;

EID: 0025907543     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/00006676-199105000-00001     Document Type: Article

References (25)

1. Balhazar EJ. CT diagnosis and staging of acute pancreatitis. Rad Clin North Am 1989;27:19-37.
2. Beger HG, Biichler M, Bittner R, et al. Necrosectomy and postoperative lavage in necrotizing pancreatitis. Br J Surg 1988;75:207-12.
3. Block S, Maier W, Clausen C, Bittner R, Biichler M, Beger HG. Identification of pancreas necrosis in severe acute pancreatitis. Gut 1986;27:1035-42.
4. Büchler M. Objectivation of the severity of acute pancreatitis. Hepatogastroenterol (in press).
5. Kivisaari L, Somer K, Standertskjold-Nordenstam CG, Schröder T, Kivilaakso E, Lempinen M. A new method for the diagnosis of acute hemorrhagic necrotising pancreatitis using contrast-enhanced CT. Gastrointest Radiol 1984;9:27-30.
6. Bank S, Wise L, Gerstein M. Risk factors in acute pancreatitis. Am J Gastroenterol 1983;78:637-40.
7. Corfield AP, Cooper MJ, Williamson RCN, et al. Prediction of severity in acute pancreatitis: prospective comparison of three prognostic indices. Lancet 1985;2:403-7.
8. Imrie CW, Benjamin IS, Ferguson JC, et al. A singlecentre double-blind trial of Trasylol therapy in primary acute pancreatitis. Br J Surg 1978;65:337-41.
9. McMahon MJ, Bowen M, Mayer AD, Cooper EH. Relationship of α 2-macroglobulin and other antiproteases to the clinical features of acute pancreatitis. Am J Surg 1984;147: 164-9.
10. Ranson JHC, Rifkind KM, Roses DF, Fink SD, Eng K, Spencer FC. Prognostic signs and the role of operative management in acute pancreatitis. Surg Gynecol Obstet 1974; 139:69-81.
11. Warshaw A, Lee K. Serum ribonuclease elevations and pancreatic necrosis in acute pancreatitis. Surgery 1979;86:227-32.
12. Büchler M, Malfertheiner P, Schoetensack C, Uhl W, Beger HG. Sensitivity of antiproteases, complement factors and C-reactive protein in detecting pancreatic necrosis. Results of a prospective clinical study. Int J Pancreatol 1986;1:227-35.
13. Jochum M, Duswald KH, Dittmer H, Neumann S. Elastase- α1 proteinase inhibitor complex (E- α1-PI) and C-reactive protein (CRP), early indicators of inflammatory processes. In: Marker proteins in Inflammation. Vol. 2, 1984:51-5.
14. Kellermann W, Frentzel-Beyme R, Welte M, Jochum M. Phospholipase A in lung injury after trauma and sepsis: its relation to the inflammatory mediators PMN-elastase, C3a and neopterin. In: Büchler M, Beger HG, eds. Phospholipase A: recent developments in methodology, pathophysiology and clinical application. Berlin, Heidelberg, New York, London, Paris, Tokyo: Springer Verlag. Klin Wochenschr 1989;67:190-5.
15. Speer C, Ninjo A, Gahr M. Elastase arproteinase inhibitor in early diagnosis of neonatal septicemia. A preliminary report. J Pediatr 1986;108:987-90.
16. Büchler M, Malfertheiner P, Uhl W, Beger HG. Leukocyte elastase in human acute pancreatitis [Abstract]. Digestion 1987;38:8.
17. Malfertheiner P, Dati F, Büchler M, Ditschuneit H. Klinische Relevanz der immunchemischen Bestimmung der Pankreas-Lipase bei chronischer Pancreatitis. Klin Wochenschr 1985;63:43-8.
18. Neumann S, Gunzer G, Hennrich N, Lang H. PMN-elastase assay: enzyme immunoassay for human polymorphonuclear elastase complexed with alpha-1-proteinase inhibitor. J Clin Chem Biochem 1984;22:693-7.
19. Mayer AD, McMahon MJ, Bowen M, Cooper EH. C-reactive protein: an aid to assessment and monitoring of acute pancreatitis. J Clin Pathol 1984;37:207-11.
20. Puolakkainen P, Valtanen V, Paananen A, Schroder T. C-reactive protein and serum Phospholipase A2 in the assessment of severity of acute pancreatitis. Gut 1987;28:764-71.
21. Gross V, Scholmerich J, Leser H-G, et al. Wertigkeit von Leukozytenelastase, C-reaktivem Protein und Proteasenin-hibitoren fur die Prognose der akuten Pankreatitis [Abstract]. Klin Wochenschr 1989,67:237.
22. Wilson C, Heads A, Shenkin A, Imrie CW. C-reactive protein, antiproteases and complement factors as objective markers of severity in acute pancreatitis. Br J Surg 1989;76: 177-81.
23. Buchler M, Malfertheiner P, Schädlich H, Nevalainen TJ, Friess H, Beger HG. Role of phospholipase A2 in human acute pancreatitis. Gastroenterology 1989;97:1521-6.
24. Gudgeon AM, Heath D, Hurley P, et al. Trypsinogen activation peptide (TAP) assay in severity assessment of acute pancreatitis [Abstract]. Pancreas 1988;3:598.
25. Gudgeon AM, Heath D, Jehanli A, et al. Zymogen activation peptide (ZAP) assay in the severity prediction of acute pancreatitis [Abstract]. Digestion 1989;43:145.