Picroliv protects against monocrotalineinduced hepatic damage in rats

Pharmacological Research

Volumn 23, Issue 4, 1991, Pages 399-407

  Dwivedi, Yogesh ^a   Rastogi, R ^a   Sharma, S K ^a   Mehrotra, R A J ^a   Garg, N K ^a   Dhawan, B N ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

hepatoprotective agent; hepatotoxicity; monocrotaline; picroliv; pyrrolizidine alkaloid

Indexed keywords

DNA; GLYCOGEN; GLYCOSIDE; IRIDOID; KUTKIN; LIVER ENZYME; MONOCROTALINE; RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG COMPETITION; HISTOPATHOLOGY; LIVER PROTECTION; LIVER TOXICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT;

ANIMAL; CINNAMATES; GLYCOSIDES; LIVER DISEASES; MALE; MONOCROTALINE; PLANT EXTRACTS; PYRROLIZIDINE ALKALOIDS; RATS; RATS, INBRED STRAINS; VANILLIC ACID;

EID: 0025905133     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/1043-6618(91)90054-2     Document Type: Article

References (35)

1. Occurrence of the pyrrolizidine alkaloid monocrotaline in Crotalaria seeds
2. The toxic actions of pyrrolizidine (senecio) alkaloids
3. The action of monocrotaline and retronecine
4. Crotalaria spectabilis toxicity in chickens
5. The histological evidence of liver damage from pyrrolizidine alkaloids
6. Toxicology and carcinogenic action of pyrrolizidine alkaloids
7. Veno-occlusive disease in Macaca speciosa monkeys
8. Veno-occlusive disease of the liver with nonportal type of cirrhosis occurring in Jamaica
9. Characterization of hepatic DNA damage induced in rats by the pyrrolizidine alkaloid monocrotaline
10. Effect of different extracts of Kutaki (Picrorhiza kurroa) on experimentally induced abnormalities in the liver
11. Hepatoprotective activity of Kutkin-the iridoid glycoside mixture of Picrorhiza kurroa
12. Hepatoprotective activity of picroliv against carbon tetrachloride-induced liver damage in rats
13. Picroliv affords protection against thioacetamide-induced hepatic damage in rats
14. Evaluation of hepatoprotective activity of picroliv (from Picrorhiza kurroa) in Mastomys natalensis infected with Plasmodium berghei
15. A simple method for the isolation and purification of total lipids from animal tissues
16. The incorporation of P 32 into the inositol phosphatides of rat brain
17. A new method for the direct determination of serum cholesterol
18. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
19. The determination of glycogen
20. Determination of glycogen
21. Protein measurement with the Folin phenol reagent
22. Phosphorus compounds in animal tissues. 1. Extraction and estimation of deoxypentose nucleic acid and of pentose nucleic acid
23. Phosphorus compounds in animal tissues. IV. The distribution of nucleic acids and other phosphorus-containing compounds in normal and malignant tissues
24. Some new characteristic color tests for thymonucleic acid and a microchemical method for determining the same in animal organs by means of these tests
25. Estimation of small amounts of pentose especially in derivatives of adenylic acid
26. Intracellular distribution of enzymes. V Further studies on the distribution of cytochrome c in rat liver homogenates
27. Carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
28. Simplified photometric methods for the determination of the blood bilirubin
29. Determination of albumin in serum and urine with bromocresol green
30. Early identification of carbon tetrachloride hepatotoxicity in albino rats
31. Biochemical changes in the rat after chronic thioacetamide intoxication
32. Experimental hepatitis induced by Dgalactosamine
33. The conversion of pyrrolizidine alkaloids to N-oxides and to dihydropyrrolizine derivatives by rat liver microsomes in vitro
34. Toxicity of pyrrolizidine alkaloids
35. Indirect hepatoxins