Alterations in cardiac contractile proteins due to oxygen free radicals

BBA - General Subjects

Volumn 1074, Issue 1, 1991, Pages 95-100

  Suzuki, Shingo ^a   Kaneko, Masanori ^a   Chapman, Donald C ^a   Dhalla, Naranjan S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

(Rat heart myofibril); ATPase, Ca2+ stimulated; ATPase, Mg2+ ; Hydrogen peroxide; Hypochlorous acid; Sulfhydryl group; Superoxide anion

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATASE (MAGNESIUM); OXYGEN RADICAL; THIOL GROUP;

ANIMAL TISSUE; ARTICLE; HEART MUSCLE; MUSCLE FIBRIL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; CA(2+) MG(2+)-ATPASE; CA(2+)-TRANSPORTING ATPASE; CONTRACTILE PROTEINS; DITHIOTHREITOL; FREE RADICALS; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; IN VITRO; KINETICS; MALE; MYOCARDIAL CONTRACTION; MYOCARDIUM; OXYGEN; RATS; RATS, INBRED STRAINS; SULFHYDRYL COMPOUNDS; SUPEROXIDE DISMUTASE; SUPPORT, NON-U.S. GOV'T; XANTHINE; XANTHINE OXIDASE; XANTHINES;

ANIMALIA; FELIS CATUS;

EID: 0025903562     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-4165(91)90045-I     Document Type: Article

References (34)

1. Depression of heart sarcolemmal Ca2+-pump activity by oxygen free radicals.
2. Mechanism for depression of heart sarcolemmal Ca2+ pump by oxygen free radicals.
3. Hydroxyl free radical reactions with amino acids and proteins studied by electron spin resonance spectroscopy and spin-trapping
4. The Acid Ionization Constant of HOCl from 5 to 35°
5. Dithiothreitol restores contractile function to oxidant-injured cardiac muscle.