Ampicillin-loaded liposomes and nanoparticles: Comparison of drug loading, drug release and in vitro antimicrobial activity

Journal of Microencapsulation

Volumn 8, Issue 1, 1991, Pages 29-36

  Fattal, E ^a,b,c   Rojas, J ^a,b,c   Roblot Treupel, L ^a,b,c   Andremont, A ^a,b,c   Couvreur, P ^a,b,c  

^a UNIV PARIS SUD   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; LIPOSOME;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACILLUS SUBTILIS; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; FREEZE DRYING; IN VITRO STUDY; PARTICLE SIZE;

AMPICILLIN; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; COLD; COMPARATIVE STUDY; DRUG CARRIERS; DRUG STABILITY; FREEZE DRYING; LIPOSOMES; MICROBIAL SENSITIVITY TESTS; SUPPORT, NON-U.S. GOV'T;

EID: 0025897324     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.3109/02652049109021855     Document Type: Article

References (14)

1. Macrophages as targets for delivery of liposome-encapsulated antimicrobial agents
2. Free versus liposome-entrapped ampicillin in treatment of infection due to Listeria monocytogenes in normal and athymic (nude) mice
3. Treatment of experimental salmonellosis in mice with ampicillin-bound nanoparticles
4. Comparative cell uptake of propidium iodide associated with liposomes or nanoparticles
5. Attachment of antibiotics to nanoparticles: preparation, drug-release and antimicrobial activity in vitro
6. Factors affecting the clearance kinetics and tissue distribution of liposomes, microspheres and emulsion
7. Degradation of poly(isobutylcyanoacrylate) nanoparticles
8. Quantitative reversed-phase high-performance liquid chromatographic analysis of ampicillin
9. Influence of conversion of penicillin G into a basic derivative on its accumulation and subcellular localization in cultured macrophages
10. Assay of antimicrobics: Laboratory test in chemotherapy
11. Stability of sodium ampicillin solutions in the frozen and liquid states
12. Stability of liposomes in blood constituents: consequences for uptake of liposomal lipid and entrapped compounds by rat liver cells
13. Liposome-cell interactions: in vitro discrimination of uptake mechanism and in vivo targeting strategies to mononuclear phagocytes
14. Effectiveness of nanoparticle-bound ampicillin in the treatment of Listeria monocytogenes infection in athymic nude mice