A New Predictive Equation for the Solubility of Drugs Based on the Thermodynamics of Mobile Disorder

Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists

Volumn 8, Issue 7, 1991, Pages 840-850

  Ruelle, Paul ^a   Rey Mermet, Catherine ^a   Buchmann, Michel ^a   Nam Tran, Hô ^a   Kesselring, Ulrich W ^a   Huyskens, P L ^b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

hydrophobic effect; methylparaben; mobile order; solubility; solution thermodynamics; stability constants

Indexed keywords

ALKANE; ALKANOL; ESTER; ETHER; KETONE; ORGANIC COMPOUND;

ARTICLE; DRUG SOLUBILITY; STRUCTURE ACTIVITY RELATION; THEORY; THERMODYNAMICS;

CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; HYDROGEN BONDING; PARABENS; PROTONS; SOLUBILITY; SOLVENTS; SUPPORT, NON-U.S. GOV'T; THERMODYNAMICS;

EID: 0025891084     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1023/A:1015891126287     Document Type: Article

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