Human papillomaviruses in the pathogenesis of anogenital cancer

Virology

Volumn 184, Issue 1, 1991, Pages 9-13

  zur Hausen, Harald ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANUS CANCER; CARCINOGENESIS; GENITAL TRACT CANCER; HUMAN; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; VIRUS CELL TRANSFORMATION; WART VIRUS;

ANUS NEOPLASMS; CERVIX NEOPLASMS; FEMALE; HUMAN; MODELS, BIOLOGICAL; PAPILLOMAVIRUS; TUMOR VIRUS INFECTIONS;

HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPES; PAPILLOMAVIRUS;

EID: 0025886714     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/0042-6822(91)90816-T     Document Type: Short Survey

References (47)

1. Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements
2. Suppressionin vivo of human papillomavirus type 18 E6-E7 gene expression in non-tumorigenic HeLa-fibroblast hybrid cells
3. A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer
4. Differential response of nontumorigenic and tumorigenic human papillomavirus type 16-positive epithelial cells to transforming growth factor β
5. Continued expression of HPV 16 E7 protein is required for maintenance of the transformed phenotype of cells cotransformed by H PV 16 plus EJ-ras
6. Histological and molecular analysis of early neoplasia
7. Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm
8. Heterogeneity of the human papillomavirus group
9. Induction of human cervical squamous cell carcinoma by sequential transfect with human papillomavirus 16 DNA and viral Harvey ras
10. Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA
11. Glucocorticoid enhanced neoplastic transformation of human keratinocytes by human papillomavirus type 16 and an activated ras oncogene
12. Inverse relationship between HPV 16 early gene expression and cell differentiation in nude mouse epithelial cysts and tumors induced by HPV positive human cell lines
13. The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
14. Wild type p53 can inhibit oncogene mediated focus formation
15. The p53 protooncogene can act as a suppressor of transformation
16. Definition of precursors
17. HPV 16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes
18. Immortalization and altered differentiation of human keratinocytesin vitro by the E6 and E7 open reading frames of human papillomavirus type 18
19. Progression of human papillomavirus type 18 immortalized human keratinocytes to a malignant phenotype
20. De novo methylation of the MyoD1 CpG island during establishment of immortal cell lines
21. Characterization of primary human keratinocytes transformed by human papillomavirus type 18
22. Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa
23. Analysis of human p53 proteins and mRNA levels in normal and transformed cells
24. Both episomal and integrated forms of human papillomavirus type 16 are involved in invasive cervical cancers
25. Human papillomavirus type 16 alters human epithelial cell differentiationin vitro
26. Chromosomal integration sites of human papillomavirus DNA in three cervical cancer cell lines mapped by in situ hybridization
27. The E6 and E7 genes of human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
28. Evolution ofin vitro transformation and tumorigenesis of HPV 16 and HPV 18 immortalized primary cervical epithelial cells
29. Transformation of human fibroblasts and keratinocytes with human papillomavirus type 16 DNA
30. Selective suppression of human papillomavirus transcription in non-tumorigenic cells by 5-azacytidine
31. Chromatin structure and transcriptional regulation of human papillomavirus type 18 DNA in HeLa cells
32. Extinction of the HPV 18 upstream regulatory region in cervical carcinoma cells after fusion with non-tumorigenic human keratinocytes under non-selective conditions
33. 105
34. Introduction of chromosome 1 1 via microcell transfer controls tumorigenic expression of HeLa cells
35. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
36. Structure and transcription of human papillomavirus sequences in cervical carcinoma cells
37. Transcription of human papillomavirus type 16 early genes in cervical cancer and a cervical cancer derived cell line and identification of the E7 protein
38. Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells
39. Influence of chromosomal integration on glucocorticoid regulated transcription of growth-stimulating papillomavirus E6-E7 genes in cervical-carcinoma cells
40. Correlation to modified human papillomavirus early gene expression with altered growth properties in C4-I cervical carcinoma cells
41. Human papillomavirus type 16 transformation of primary human embryonic fibroblasts requires expression of open reading frames E6 and E7
42. Association of human papillomavirus types 16 and 18 E6 proteins with p53
43. Human cervical and foreskin epithelial cells immortalized by human papillomavirus DNAs exhibit dysplastic differentiation in vivo
44. Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines
45. Cell-virus gene balance hypothesis of carcinogenesis
46. Intracellular surveillance of persisting viral infections: Human genital cancer results from deficient cellular control of papillomavirus gene expression
47. Papillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers