Structure/Activity and Molecular Modeling Studies of the Lophotoxin Family of Irreversible Nicotinic Receptor Antagonists

Journal of Medicinal Chemistry

Volumn 34, Issue 6, 1991, Pages 1798-1804

  Abramson, Stewart N ^a   Harold, Edward E ^a   Taylor, Palmer ^a   Trischman, Jacqueline A ^b   Tapiolas, Dianne M ^b   Fenical, William ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BUNGAROTOXIN; BIPINNATIN B; LOPHOTOXIN; NICOTINIC RECEPTOR; TERPENE; TOXIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; COMPUTER SIMULATION; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG RESEARCH; DRUG SYNTHESIS; NONHUMAN; PLANT; PRIORITY JOURNAL; TORPEDO;

ACETYLCHOLINE; ANIMAL; BINDING, COMPETITIVE; BUNGAROTOXINS; CHOLINERGIC ANTAGONISTS; CNIDARIAN VENOMS; MODELS, MOLECULAR; NICOTINIC ANTAGONISTS; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TORPEDO;

EID: 0025885159     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00110a007     Document Type: Article

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